Entrez gene ID | | 83988 |
Official gene symbol | | NCALD |
Full name | | neurocalcin delta |
Aliases | | ,MGC33870,MGC74858, |
Gene summary | | This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q22.2 |
Gene position | | 103137135 - 102698770 Map Viewer |
Gene orientation | | minus |
Gene size | | 438366 bp |
Gene sequence |
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OMIM ID | | 606722 |
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