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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CASP9 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID842
Official gene symbolCASP9
Full namecaspase 9, apoptosis-related cysteine peptidase
Aliases,APAF-3,APAF3,CASPASE-9c,ICE-LAP6,MCH6,
Gene summaryThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.3-p36.1
Gene position15850790 - 15818791  Map Viewer
Gene orientationminus
Gene size32000 bp
Gene sequence
OMIM ID602234