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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STK24 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8428
Official gene symbolSTK24
Full nameserine/threonine kinase 24 (STE20 homolog, yeast)
Aliases,MST3,MST3B,STE20,STK3,
Gene summaryThe yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM]
LocationChromosome: 13   Locus: 13q31.2-q32.3
Gene position99229396 - 99102455  Map Viewer
Gene orientationminus
Gene size126942 bp
Gene sequence
OMIM ID604984