Entrez gene ID | | 8436 |
Official gene symbol | | SDPR |
Full name | | serum deprivation response |
Aliases | | ,PS-p68,SDR,cavin-2, |
Gene summary | | This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. |
Location | | Chromosome: 2 Locus: 2q32-q33 |
Gene position | | 192712006 - 192699031 Map Viewer |
Gene orientation | | minus |
Gene size | | 12976 bp |
Gene sequence |
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OMIM ID | | 606728 |
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