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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RASAL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8437
Official gene symbolRASAL1
Full nameRAS protein activator like 1 (GAP1 like)
Aliases,RASAL,
Gene summaryThe protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq]
LocationChromosome: 12   Locus: 12q23-q24
Gene position113574044 - 113536624  Map Viewer
Gene orientationminus
Gene size37421 bp
Gene sequence
OMIM ID604118