Entrez gene ID | | 8439 |
Official gene symbol | | NSMAF |
Full name | | neutral sphingomyelinase (N-SMase) activation associated factor |
Aliases | | ,FAN, |
Gene summary | | This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants. |
Location | | Chromosome: 8 Locus: 8q12-q13 |
Gene position | | 59572404 - 59496063 Map Viewer |
Gene orientation | | minus |
Gene size | | 76342 bp |
Gene sequence |
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OMIM ID | | 603043 |