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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DHX16 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8449 Official gene symbol DHX16 Full name DEAH (Asp-Glu-Ala-His) box polypeptide 16 Aliases ,DBP2,DDX16,PRO2014,PRP8,PRPF2,Prp2, Gene summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 6   Locus: 6p21.3 Gene position 30640830 - 30620896  Map Viewer Gene orientation minus Gene size 19935 bp Gene sequence >DHX16:complement(2132939..2152903):Length=19965 CACCGTAGTGCTTAGAGGCCGAAAAAGTACAGCCCCTTCCGGGCTCCGCGGTACGGGAAG ACAGCTTTGGGATGTCGGAAGATCCTAGAGGTCCCAAGGTAGCTGACTTGCGAAGCTGAG GCTCCAGCCGAGGGCTCCAGGCCTCTGACCGGCCCAGCAGTGAGCGCGGCTGCCCGACGC TTCAGGGCCGGGAGCAGGGAGCGTGAGTCGCCATGGCGACGCCGGCGGGTCTGGAGCGCT GGGTTCAGGACGAGCTGCACTCGGTGTTGGGGCTGAGCGAGCGGCACGTCGCCCAGTTTC TGATCGGTACCGCACAGCGCTGCACCTCTGCCGAGGAGTTCGTGCAGCGCCTACGAGACA CTGATACCTTGGATCTCAGTGGGCCGGCCCGGGACTTCGCCCTGAGACTCTGGAACAAGG TGTCGGCAGGGGTGGGGAGGGGCCCTGTGATTTGTCCCGGTGAGGCTGGCCTAACGGTCC ATCGAGAAGTTAAGAAAGCTCAGTTCACAAGCACTTATTCTTTGTCCGTTGTCGCGTAGG TACTGTGCTAGCTGCTGGACGCCCAGCTCAGTGGAGAAGATTGAGGAGGGCTTAGGTGTG TCGGGTTAAGCGCAATAGAACGGTGTTTCTCGAACTCTTAACATGCATCCAAGGTTCTTG TTAAAATGCAGATTGCGATTCAGTAGGGATCTTAGTTTCTGCATTTCTTTCTTTCTTTTT TTTTTTTTTGAGAGACACAGTCTCGCTCGCCCCGTCGCCCAGGCTGGAGTGCGGTCGTAA GATCACGGCTCACTACAGCGTCGACCTCCCTGGTTGAAGCGACCCTCCCACCTCATCTTC CCCGGTAGCTGGGACTACGGGCGCGCGCCACCACCCCCGGCTAATATCTTTTATTTTTAT TTTTATTTTTAGAGATGAGGCCTTGGTGTGTTGCGCAGGCTGGTCTCTAACTCCTCAGCT CAAGCAATCCTCTCTCAGCCCCCTCAGAGTGCTGAGATTACAGGCGTGAGCCACCATGCC CGGCCCCCCTCATCTTCTGAACTTCCTTTCAGTCGTTTAATTAACAGAGGGGGCCGGGTG CAGTGGCTCACACCTGTAATCCCAGCACCCCGGGAGGCTGAGGCAGGAGGATTACTTGAG CCCAGGAGTTCGAGACCAGCCTGGGCAACATGGCGAAACCTTCGTCCTACAAAAAAATTA AAAATTAGTTGAGCGTGGTAGTGTGCACCTGTGTTTCTAGCTACTTAGGAGCCTGAGGTG GGAGGATCCCTTGAGCCCAAGAGGGACAGAGTGAAACCCTGTCTGTAAAAAAAAATAAAA AACCCCATTCAGGATGATGAAGATGGGGTGAAGCCATGAGGAAGAAAGAGAATGAATGCT GGTTAGCTGGTTTAAAACTAAGTAATTGTGCCCGGGTGCGGTGGCTCATGCCTGTAATCC CAGCACTTTGGGAGGCTGAGGTGAGTGGATCATGAGGTCAGGAGTTTGAGACCAGCCTGG CCAACATGGTGAAACCTCATCTCTACTAAAAATACAAAAATAGTCGGGCGTGGTGGCATG TGCCTGTAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGC GGAGGTTGAAGTGAGCCGAGATCACGCCATTGCCTGACAGTGGGGCCGGGCCGCGGGGGC AGGAAAGACTAAGTAATTGCTTAAATTAGGAACAGAGCTAAGTGGGAGGGCAGAGATCAG GAGTTGCTCAGACCTCCTTATCTTCCCCTCTACTGACAGGTACCACGAAAGGCAGTGGTA GAAAAGCCAGCTCGGGCAGCAGAGCGAGAGGCCCGGGCCCTGCTGGAGAAGAACCGATCT TATAGGTTACTGGAAGACAGTGAAGAGAGCAGTGAGGAGACTGTGAGTAGGGCTGGAAGC AGCCTCCAGAAGAAACGTAAAAAGCGGAAACACCTCAGGAAGAAGCGTGAGGAAGAAGAG GAGGAAGAGGCTTCTGAGAAAGGGAAGAAGAAAACAGGGTAAGTCAGAAGCAGGGTGAGA GAGGATGGGGCAGGCTGAAGTGTTCTCTATGCCCTTATTTAATCCCCTGGATGGGCTGCA GGGGGAGTAAACAGCAGACAGAGAAGCCAGAGTCGGAAGATGAGTGGGAACGGACAGAGC GTGAACGCCTTCAGGACCTGGAGGAGCGTGATGCCTTTGCTGAGCGGGTTCGACAGCGGG ACAAGGATCGGACTCGAAATGTCCTGGAACGGTCAGACAAGAAGGTGAATAGGAGCAGCA TGTTCTGTAAATCCCCAAGATCCCAGGGTGAAATCTGAGGTTGGCTGTGAGTGCAGAGAT AGTGATCTCTGGGAAGACAAGGGGCTGTCTCTAGTGAGATGTTCACCTCTGTGGTGAGAG AAGCCCTGTGCATCCTGTGGCTAAGACAACTGTCTGCTGTACCTGCAATCAGAGAGATTC CTCACTGAGAGGGGACATTTTTTGTGTTAGGGCGCATCTGAATGATCCTTGTGATTCTAG AGGGGAGCAGCTGTCAGTGTGGGGGCTCTTTGGCCTCACACCCCTCCATTCTTGTTTTTT CTTCTAGGCTTATGAAGAGGCTCAGAAGCGCCTCAAGATGGCCGAGGAAGACCGGAAGGC CATGGTGAGTCCCAGGGCCTAGGGAGCCAAGATCAGAAGACAAAAGGAAAGACTTTCTGA TAGAGTGTATAGGGAGAGAGGATACAGAGGAAGCACAGTGTGGATGCTGATGGGGTGGTC AGGTTTCTAGAAGAGGGGCTTGGTTGTTAGGAGCCAGCTGAGGATAGACTTATGTTGTTG AGGGAAGGATCCTTCTTAAGTTGTAGGGGGAAGGAGGCTACCCATAAGTCCTCCTTGACT CTTAACTTTAGGATCAAATATACTCTATTAGTGAATGAAATTGTGAGCTTTCCCTATTCC TGAGTCCTAATGAGATATGAGGCAGCTGGAATGTTGTCAAGAAGGTTGCTGGAGGGCAAG GGCAGGGCAGCAGTCCCACTGTACAGGGATGTGCTGACCATTCAGCTTAGGCACACCATC TCCAAATACCTTCCCACCACCTAATTCCTGCACCCCTTATGTGGCTTTGTGATCTCCCTG TGTCTTCTCACTGGACAGGGACAGAGCCCTTGTAATTCATAAACTGGACTTTTTATGGTG TGAAACTAGGTAGGGTAAGCTGTTTTCCAAAGGCCTGGTCTTGTCAAGTAAAGTCACACT TAGATTCCCCAATACCCCAATAGAATTTTGAGACTCTTGAAGTTCCTTTTTTTTTTTTTT TTTTTTTTTAAACCTTTTTTCTTTTTTTTGAAACGGGGTCTTGCCCTGTCACCGAGGCTG GAGTGCAATGATGCGATCTCGGCTCACTGCAACCTCCGCCTCCTGAGTAGCTGGGATTAC AGGCGCACACCACCACGCCTGGCTAATTTTTTGTACCTTTAGTAGAGACGGGGTTTCACC ATGTTGGCCAGGGTGGTCTCGAACCCCTGACCTTGTGATCCACCTGCTTTGGCCTCCCAG AGAGCTGGAATTACAGGCGTGAGCCACCATGCCCAGCCTTCTTTTTATTTGTTTTGTTTT ATTTTTTATTTTTATTTATTTATTTTTGAGATGGAGTCTCACTCTGTTGCCAGGCTGGAG TGTGGTGGTGCGATCTCAGCTCACTACAACCTGTGCCTCCCTGGTGGAGGAATCAAGCGA TTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCCTGCAGTACCACACTCGGCT AATTTTTTGTATTTTTAGTAGAGGAGATTTCATCATGTTGGCCAGGATGGTCTTGATCTC TTGACCTTGTGATCTGCCCGCCTTGGCCTCCCAAAGTGTTGGGATTATAGGCATGAGCCA CTACGCCTGGCCGTTTTTACTTTTTAAAATTCATTTATTTATTTTTTTGAAACAGAGTTT TGCACTTGTTGCTCAGGCTGAAGTGCAGTGGCGTGATCTTGGCTCACTGCAACTTCCACC TCCCGAGTTCAAGCGATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATTACAGGCATGA GCCACCTCGCCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCA GGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGG GATTATAGGCGTGAGTCACCACGTGCCCGGCCAACTTTTGGAGTTCTAAGAATGGCCTAC TGGTTCCCAGGTCTCTCCTGACCAATTTATCTCATATCTCTTCCTGAAATTGACTGTGGT TAGGCTTCTGGGACATCTCAGTGCAGTTGTGGTGGTAGTGGTGTTACTGTTTTGGCCTGA ATTTAATTTTTCGGGTTTTTTTTGAGACAGAATCTCATTCTGTCGCCCAGGCTGGAGTGC AGTGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGCC TCAACCTCCCGAGCAGCTGGGACTACAGACATGCACTAGCATGCCTGGCTGATTTTTGTA TGTTTAGTAGAGATAGGGTTTCACCATGTTGGCCAGTCTGATCTCAAACTCCTGACCTTT GGCGATCCACCCCCCTCGGTCTCCCAAAATGTTAAGATTACAGGCGTGAGCCACTGTGCC CAGCTGTAATTTTTCTTTTTCGATTACAAAAATATTTAAGCACATAGGGAAGTTGAAAGA ATAGAACAAAGAACACTCATAGACACTATTCAGATTGAAAAATGGTTAATACTATGGGTA GTATTTGCATTGTAATTGTAAATGTGGTATGTTTTTTCTTTTCAGACCATTTAAAAGAGT CTTAGACATCATGGCGTTTTATCTCTAAGTACATCAGTGTGTACCTGCTAAGGATAAAGA TATTGTCCTCTAAAATCAGAATGCTCTTGTCACAGTCAGGAAGTTGAACAGTAATTCTTA TGTATCGACTAAGATCTCTCTACAATAAAAGATACCCTCATTACCCTCAAAATAACTTTA ATGACTGCTTTTTCCTAACAAGAATGCAGTCAAGGTTCATGCATTGCATTTGGGTCTTAG ATGTTAAGTTTGTTTCTCTCTCTGTCTGTCTCACCTTGCAGTGTCCTACATTCTGGATTT GCCTGATTCTTATCTTGTGGTGTTAAGTACTTCTCTGCCCTGTGCTTTCTTTGAAGCAGG AATTGGGTCTAAAGCTTATTGACACTCAGATTAAACAGTTGTGGCAGGAACACTTCTTGG GCGGTGATGTGCACTTCATATTATGTCATATCACGGGGACATACTATCCAGTTGTGTATC TATATATTAGTATTAATATCCTTTCTACCAATAGCCTTTCATCAAATGCTTTTAGAAGCC ACTGGTAATCCTTTCCTGAACATGTTATTTTTATTGGGGATTGCAAAATGGTGATTTTTT TTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAACGGTGCGAT CTCGGCTCACTGCAAGCTCTGCCTTCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCTG AGCAGCTAGAACTACAGGCGCCTGCTGCCACGCCCGGCTAATTTTTTGTATTTTTAGTAG AGATGGGGTCTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCCTCTT GCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCGAAATGG TGATTTTTTGATTCTGTCATTCCTGTTACGTGTATTGGCTAGAATTTGTCTATAAAGAAG AGCTTTTCCTCAACAACTAGGAACAAGCTACAGTTCCTTCTTAAAAAGGGTAAATGTTTG TTTCCTTTTAAATACGAATTTTTAGAGTAAGGCGTTTGCTGTAACAGTCATTTCACTGGT GACAGATTTTTTTCCCTTGTTTTTTGTTTGTGTGTGTCAAATTGGACTCATGAATTTTTA TTTTTCAGTATTTTATAATCTCACATCATTATTCTTTTTAATGCTCAAATGGCTCTGATT TTTTGCCCATATTAAAAAAAAAATCTATCTGGCTCTTCCATGGAAGGAATATTTGACTGT GGTACCCAGATTAGGTCATGATCATAAACTGCATTTTAAGTCTTTACAGAACAAACAAGA AAAGCCAAACAACTAAATAGAACCAGGCCCCTTAAGGGTAGAACAGCAGAGGGGCTTTTT TTTTAAAGATGCAGTTTTGTTCTTGTTGCTCAGGCTGGAGTGCAATGGCGTGAGCTAAGC TCACTGCAACCTCCGTCTCCCGGGTTCAAATGATTCTCCTGCCTCAGCCTCCCGAGTAGC TGGGATTACAGGTGCCCACTACCATGCCCAGCTAATTTTTGTATTTTCAGTAGAGACGGG ATTTCACCATGTTGGCCAGGCTGGTCTCTAACTCCTGACCTTAGGTGATCCACCCACCTC AGCCTTTCAAAGTGCTGGGATTACAGGTGTGAGTCACCACGCCCACCCAGCCACCAGAGG GGCTTTGACCTTGCAGTAGAGGAAGTTGTGATCACAGAGAGGATGATGTCATAGTGGGAG GACTCCTGGCAGGAAAGGGCCTTATAGATATTGCCAGTTTTCTGCTGTCATCCATAATGT GTCCTGAAAAGTTTGTATCAAAGGTAAATGTGTAGAAACTAAGTGAGACACAGCATGGTG AAGAGAGGTTAGTACCAGAAAGCCAAACATCCCTGATTACATTTGCCTTACAGAAACACT CTGATGCTGTAGTCCTAACTTTTTATAATCAGTTTTTCTCCCTTCCTCAAACTACAGTCA TTCCGTTTAAGACCAAAGAACATCTAACTGGGGCTGAAGATTGCCTCCTGTTGGCCCCCT CACTGGTTTCTATCTTTGTCTGAATTGTTTTCGGTTTGAGTCCTGTGCTTCTAAATGCTG GATTAGCCTTTTATTTTCCCCCTTTCCACTAATTTGAATAAAATGGCAAGAGTAAAATAT AAGCTACGCAGACATCTCCCTAGTGCATCTATATTAACAAAGATGATAATGCTGCCTAAG AGGACTTTCCAGCTGGATTCTGCTGCAGGAAGATACGATGTGGGGTCAGCATGTAGCATC CAAAGAGGCCCAGATTTGAGTATGTCATTGTTTTGGTTGTGCATTGCAGAGGGAAGGTAG AGGGTGCATCCTGAGGTTCTCATGCCTGCCTGTCAGGGGATTTTTCCCTTGTAGGGATTG GTAGAGAAAGGGGTTGCTCCTCCAGCAAGATGAGGATTCGACTGTCCTTTCCCAACTCAG GTCCCTGAGCTGCGGAAGAAATCTCGCCGAGAGTACCTGGCTAAGCGGGAGCGAGAGAAG CTTGAGGACCTGGAGGCGGAGCTGGCTGATGAGGAGTTCCTTTTTGGGGACGTGGAGCTG AGCCGGCACGAGCGGCAGGAGCTCAAATATAAGCGGCGAGTGCGGGATCTCGCCCGGGAG TACCGGGCAGCTGGGGAGCAGGAGAAGCTGGAGGCCACCAATCGCTACCACATGCCCAAG GAAACCCGAGGACAGGTGAGGTGAAGCGGCGTCTGCTTCAGCCTTGGTCCCCAAGACAAG TTGTGGGGAAGGCTTCAGGGGATTGGGCAACACGTGGGTCATCCCCTTTCTTGCCTTGCC GTTCCCAATGGGCAGTGGGCGGGGGTAGTAATGGGAAGAGGGGAGAGGGCAGAGAGGACA TCCTGTTTTTGAGTCTTCACATATCCCCTCTCTCTGTAGCCAGCCCGAGCTGTGGATCTA GTGGAGGAGGAATCAGGAGCCCCTGGGGAGGAGCAGCGGCGCTGGGAGGAGGCGCGGCTT GGGGCAGCGTCCCTGAAGTTTGGGGCCCGAGATGCTGCCTCTCAGGAGCCCAAGTATCAA CTGGTGCTGGAGGAGGAGGAGACCATTGAGTTTGTCCGGGCCACTCAGCTCCAGGGTGAT GAGGTAAGAGGGGAGCTGGGAGACTTTCTGAGGAAGACCCGTAGCGAGCTATTTAGCTCA CACCTCCTTCTCTTTCCTTAGGAGCCGTCAGCTCCACCCACTTCAACTCAGGCCCAGCAG AAAGAGTCCATCCAGGCCGTCCGCCGCAGCCTCCCGGTGTTCCCATTTCGAGAGGAGCTC CTGGCTGCTATTGCAAATCACCAAGTCCTCATCATTGAAGGCGAGACAGGCTCAGGGAAG ACCACCCAGATCCCGCAGTATCTCTTTGAGGAGGTACAGTCATCTCACCCTTCAGCTTGC CAGGGCACCTGGCATCAATGTCCTCATTCCTGTCAGAGCTCCTTTTACATTATATTTTTA GTAGTCACTTACCTATCTTTTCCACTAAATTGTGAAATTCTTGAGAGTAAAGACCATACC CTTTTCACATTTCTGTTCTCACTTCCTGCATTCATTTCATTTGGAAGGACGGGTAGATGG ATAGGTGGAGTGGGGCGTGTATAAATGTGGACCTCCCTATGCTCCAACGTGGCCAAAAAA CAAGGAGTTAAAGGACTATTTTCCTGCCTTTTTGTTAGTTTTTTTTTTTTTTTTTTGGAG ACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTTACTGCAA CCTCTGACTCCTGGGTTCAAGGAATTCTCCTGCGTCAGCCTTCAGAGTAGCTGGAATTAC AGGCATGCGCCACCACACCTGGCTAATTTTTTAGTAGAGATGGGGTTTCACCATGTTGGC CAGGCTGCTCTCGAACTCCTGACCTCAAGTGATCCAGCCACCTCAGCCTCCCAAAGTGCT GGGATTACAGGTGTGAGCCACTGTGCCTAGCCCCTGCCTTATTTTGGAGACAGGCTCTTG CTCTGATGCCCAAGCTGGAGTGATGTGGCACCATCATGACTCACTGCAACCTGGGACTCC TGGGCTCAAGAGATCATCCCACCTCAGCCTCCTGAGTATCTGGGAGGTGCACACCACCAT GCCCATATTAAACATTTTTTGTTTTTTTTTGAGGTGGAGTCTTGCTCTGTCACCAGGCTG GAGTGCAGTGGCGCGATCTTGACTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCT CCTGCCTCAGCCTCCTAAGTAGCTGGGACTACAGGTGCGTACCACCACACCCAGCTAATT TTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCAATCTCCTG ACCTCGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGAGTTACAGGTGTTAGCCACTG TGCCTGGCCTGAAATTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAG GCTGGAGTGCGGTGGCATGATCTTGGCTTACTGCAACCTCTGTCTCCCAGGTTCAAGCGA CTCTCCTGCCTCAGCCTCCCAAGTAGCTGGAAATACAGGCATGCACCACCATGCTCGGCT AATTTTTTGTATTTTTAGTAGACGGGGTTTCACCATTTTGGCCAGGCTGGTCTCGAACTC CCAACCTCAGGAGATCCGTCTGCCTCGGCCTCCCAAAGTGCTGGAATTGCAGGTGTGAGC CACTGTGCCTGGTCAAAATTTTGAATTTTTAATTTTTTTGTCACACTATGTTGCCCAGGC TGGTCTCGAACTCCTGAGCTCAAGCCATCCTCCCACCTCAGCCTCCCAAAGTACTAGGAT TACAGGCATGAGCCACTGTGCCCAGCCTTCCTGCTTTTTTACCTTAGCTGGCTCTGTCTC AGCTAATCTGTTCTTTTCCAGCTCAAGTCTAGCAGAGTCATGAACTTAATTACCCAGAGC TGGGTGAGGACCCCCTTTGAGGGCCCTAGGTCTGTCATCCTATCTATTTGCCCTTCTTTT CTGGTTTTCAGCATCTGTCTTTTCCTCCTTTTCTCCTGCCTGGTTTTTACAACTTCTTTC TCTGAAATGTACCTGGTCCCAGGGTGCATATTTAGTAAAGGGCAAACTTCTTCTTTTTTC TTTGTCATTCAGGGTTATACAAACAAGGGTATGAAGATTGCCTGCACCCAACCCCGGAGA GTGGCTGCCATGAGTGTGGCCGCCCGAGTGGCCCGGGAGATGGGTGTGAAGCTTGGGAAT GAGGTGAGATTTCTAGGGAACCGGGGGGTAGAGTCTGGGGTCTGTGACTCAGTCTACAGT TCCCTCAGGTCCCTACAGCAGAAGTCTTGGTGCTGCCCCACTTCACCTTTCCCCAAGTTC CTTTCAGGGCACACCAGCCCACACTTGGTTGCTAATGGTTCCCTTGACCAGGTTGGCTAC AGCATCCGCTTTGAGGACTGCACATCAGAGCGAACTGTCCTCCGCTACATGACAGATGGG ATGCTTCTCCGGGAGTTCCTCTCTGAGCCTGACCTGGCGAGTTACAGGTATCTCTAATCT CTGGCCTTTCTCTCCCTTCTTCCCACCCAGCCAATTCAGCCATTGTCTTCTGATTAATCC ACCCGTTCTTGAATCTTTGTGGTTCAAATGGTCCTTGAACTGACCTCCAGGTACCACGGA GATGGGGCTGGAGGACAGAAGAGATTGTAGAGAAAGCCTCTTCTTTCCCCATTCATCTCC AGGGTTTAGAAAACAACCAGGATAGCAGAGCATTGCTGCCGAGACTTGAAATACCGTGTG AAGACCATTTGAAAACACTTGGAATGCTCAGCTCAGAGGGAGAAACAGGAAGCATCCTGG TTCCCTCTAAATATGTGAAGGCTGTTACATGGAAAGAAGGATCAGATTGTTTTATGTGAC CCTACACGACATAGCTAGGAGCCATGGGGAGGTTACAGGGAGACAGATTCCAACTCAATA CCAATGGCTGAGTAACCCTCAGAGTGGTGGAGATTGCAGGGCCTGTCAGAGTGGTTGGAC TCTGGGTCTTGGCCCTCCACACAAGTCTTGGGTAGCTTGGTCTGTGAATAATGAGCTCTT AGTGCTGGAAATGGCCAAGCAGGGGTTGGTTGAACATGTGTTGAGGGGGAAAAGGGATTC ATGAATGTAATGGGGGTGGGGTCAGGCCAGCTGAACAATATGTGCCTTTTTGACTCTTCA GAGGCTGTGAATTTCTGGTCTTGGAAGATCACAGTGGAGCAATTGGACAGATAGGATTTT ATCCTTCATATCCCTTGCAAAAGATCTCTAAGAACCCATGGAGAGCCAGCCAGCGCAAGA GTGTCTGATGCAGATGTTTTTGCCCATCGAGCCAGCCTGCTTTGTGGAATGGCTGGGGAC TTCACCATCACAGTTAGGGTTAGGCACAAAGAGTTGAGGTCAGGGAGGTGGGTAGGGGAA GATGGGGATGAGTTCCTGGGACTTGGCTGCCACCCAGAAAAGCCAAAGAACAAAGAGAAA GAAGGTGTCATGCACATAACTGAGTTAGGAGGAAACCAAGGAGCATGCAGAGTCCTGTGA GAGTTGAGGTAGAAAGGCTTAACTTGCTCCTGTCTCCAAAAGAAGAAACAGTCAAGAATG ATGCCAGCAGCAGTTGTCCCACAGGACACCAGGAGCTTCTAGGCTATTTGAATCACAGCA GCTCAGGTCTATTACCCCCAGTCAGCCTTGCTGGCCCACCCTTATTGAAAGGGACCCTGC CTTCCACTTTTTTTTTCCTTTAAAACGTATCAGCCGGGAGCGGTGGCTCACGCCTGTAAT CCCAGCACTTTGGGAGGCAGAGGCAGGCGGATCACGAGGTAAGGAGATCAAGACCATCCT GGCTAACACGGTGAAACCCCGTCTCTACTAAAAAATATAAAAAATTAGCTGGGCGTGGTG GCGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACGCAA CCCAGGAGGCGGAGCTTGCGGTGAGCCGAGATCGTGCCACTGTACTCCAGCCTGGGCGAC AGAGTGAGACTCTGTTTCAAAACTCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCA CAGTGGCAGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGTGTGAA CCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCATGCCACTACACTCCAGCCTGCAACAG AGCAAGACTGTCTCAAAAAAAAAATCCTTCCACTTTTTCTTTTTTCTTTTTTTAGATGGA GTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTGCAACCTCT GCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCG TCTACCACCACATCTGGCTAATTTTTTTTGTATTTTTAGAAGAGACGGGGTTTCACTGTA TTGGCCAGACTGGTCTCGAACTCCTGACCTTGTGATCCACCTGCCTCGGCCTCCCAAGGT GCTGGGATTACAGGCGTGAGCTACCACCATGCCCAGCCTAAAACATATCCTTCAACTTTT TCTAGTAAGAGCAGCTGCTGAGTCTAAGCAGACTCTTGACTGAACTAGAGGGTATGGCTA ACTTGTCCTGGCCTCAGTGTGCAGCCTCTACATCTTGTTTCCTATTATCTGCTGAGGCTG GGATAGGTTGCAGATCATGGGGCCCTGGCCTTCTCTGACTTTCTGTTGCTCTACATAAGT GGGATGGCTGACTTCTCCTTAGAGCCCCCTCCGTCAACAGTCATTCTTGAACTCTTTGTG TCCATTACTCCCCTCTCATCCAGTTAACCCTGGTGTCTGATACTGCATTGCCTAGCGCTC TTCCCTCATTGCTCTCCTATTCCCTCCCCAGCGTGGTGATGGTGGATGAGGCACACGAAA GGACCCTACACACAGACATTCTCTTTGGATTGATCAAGGATGTTGCTCGCTTCCGACCTG AGCTCAAGGTCCTGGTGGCTTCAGCCACAATGGACACTGCCCGTTTTTCCACCTTCTTTG ATGACGCCCCTGTGTTTCGAATCCCCGGACGCAGGTTTCCTGTGGACATCTTCTACACCA AGGTGCCCCCTCAGGGAGGATGGGCTTAAGTCTGTGGCAGAAAAGCTGAGGCCTTTGGAG AAGGTTATCCTGTGGAGGGAAAGATGGAATGGAAGGTTCAAAGGGGAACTAGGATAAAGT GTATGTTGAATTGGGAGGAGAGGAAAGGTTTGCCTAAGCAGGTGGCCCTCCTGTGACCCC ATCTCTTTCTGCTCTCCAGGCTCCAGAGGCTGACTACTTGGAAGCTTGTGTAGTATCTGT GTTGCAGATCCATGTGACCCAGCCCCCTGGGGATATCCTGGTGTTCCTGACAGGACAGGT GCCTGACATGGTGGGGAGAGGGGATGATGTATCCCAGGGGAAGACAGGGCCGGCATGTTG GCCTTCTGTGACTCTGGGACCCCTGCTGCTCTCCCTACCCTCTATCCAGGAGGAGATTGA GGCTGCCTGTGAGATGCTCCAGGATCGCTGCCGCCGCCTGGGCTCCAAAATCCGGGAGCT CCTGGTGCTGCCCATTTATGCCAATCTGCCCTCTGACATGCAGGCCCGTATCTTCCAGCC CACACCACCTGGGGCACGAAAGGTCAGTTGGAGAAACCCACACTCTTCACCCCTGTGCTT CCCACAACTAGTAGTGAAAAAGCTGTGTGCCTGCCCCATGCAAGGTGAGTCCTGCGCACT GCTGCACACAGCTGAGGAGCAGCCAGTCCCTTGTTCCTGGGACTGAAGAGAGGAGAAATA TGGTGTGAACCAAGAGAGAGCCAAATATGTGATCTGGAAAGTATGCACAGTAGATTCAGT GGAGAAGGGAAGTCCTTGATGTGCTAAGAGGTGGGATTTGATATGGACCTTTAAGAGAAA TGTCTGAGGTCAGGTGCGGTGGCTCACGCCTGTAATCCCAGGACTTTCGGAGGCTGAGGT GGGCGGATCACTTGAGGTCAGTAGTTCGAAACCAGGCTGCCTAACGTGGTGAAACCCTGC CTCCACTGAAAATACAAAAATCAGCAGGGCATGGTGGCGTGCGCCTATAATCCCACCTGT TTAGGAGGCTGAGTCATGAGAATCGCTTGAACCCAGGAGGAGGAGGTTGCAGTGAGCTGA GATTGTGCCACTGCACTCCAGCCTGGGTGACAATGCGAGACTCCATCTCAAAAAAGAAAA ATGGCTGAGAAGTCATCAGAGGAAGGCCCAAGGTATGTTTGAGGTCAGAGTGTGAGCTAG TAGGCTTAGTGGGAGGTTCATGTGGTGAAGGAGTAGGAGACAAGGCTAAAAACAATTTGG GGCTAAGATTAGGGAGGGCCTTTGATGACAGGAAAGTTTGGACTTTATTTATTTTTCTTT TTTGAGACAGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCAAGATCTCGGCTCA CTGCAGCCTCCACCTCCCAGGCTCAAGTGATTCTTGTGCCTCAGCTTCCCAAGTAGCTGG GATTACAGGTGTGTACCACCACCCCAAGCTAATTTTTTTTTTTTTTTTTTGAGATGGAGT CTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCACCAACTCTGCTCACTGCAACCTCTGC CTCACAGGTTCAAGCGATTCTCCTGTCTCAGCCCCCCAGTAGCTGGGATTACAGGTGCCC TCCACCACGCCTGGCCAATTTTTTGTATTTTTAGTAGAGATGAGGTTTCGCTATTTTGGC CAGGTTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCT GGGATTATAGGCGTGAGCCACCATGCCTGGCCAACACCCAGCTAATTTTTAGTAGAGATG GGGTTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGGACTCAAGTGATCCGCCTGCC TTGGCCTCTCAAAGTGCTGGGTTACAGGCATGAGCCACTGTGCTTGGCGAAGTTTGGACT TTAGACAGCTGAGTAGCAGTCAAAGGATTTTGAGCAGAGATATAACTTTCATTCAACAAA TATTTAATGAGTTCCTTCTGTGTGTCAGGTACACAGGGGTTGATGATACAGTGATGAACA AAACAAAGTCCTTAGCCTAACAAACTTGCACTTGTGGTCTATCGGGGAAGCAGTGGATGC ATAAATACATATTGTCAATTTGTGGCCAGTGCTATGAAGAGATACAAGGCAGCATAGTAG GATGGAACTTGACTCTGTGGGGTGGGAGTGAGGACTGGCATGAAGGTATTTTCCTTGGGG TGTAGGGAGGGCCTCTTCAGTAAGGGGAAAGTGGAATAGAGACCCAAACCAGGTGAGGGA GGGAGCCAGGCTGATATCTGGGAGAAGAGTATGCCAGACAGAGGGAATAGCTGATGCAAA TGATCCAGTGAGGAGTGCACTTACTTGGGCAGAGCAAAGCAGTGTGTGGGAGGAGTGAGG GAGGTGGTGGAGTGCTAGCAGATGAGGTCAGAAAGGCAGCTGGGGTAGGTGATCCAGGCT TTTAAGGGGCTTGGATTGAATTCTAGAGTAGGATAGGAAGCCACTGAAGGATGGGGAGTG ATGTGACAGGTTTGTATTTTAAAAGGACCATCCTGGATGCCATGTGACAGAGGCTAGGAG CAGAAGCAGGGATACACGTTAGGAGGCTCTTACAGGAAGTGTTGTGTGAAGACGAAAGCG GTGATGGGGAGGATCGGGCAGGAACTTGAACACCCCCATTTCCCATCTCTGAAAAAAAAA AAAAACCCTAAATCCTCTTCTCCATTTCCTTTCCTCCTATGGCCCTGCTGACTCCCAGCC CCCACTTCCCTGTCCCCTGTCTTCTGGCCTTGTCCCCTGCTCCTGACCTTGGATACTACT AATTCCCTCAGCTCCTGCCCCTTACTGCAACTGCTTCACTACTCCTAACTTTCCAAGATT ACTTTTTCTGGGTAACTAGGTAGGTGGGGTCACTGGGTGACCCCATATCCTATCACTCAG GTGGTTGTGGCAACGAACATTGCTGAGACATCACTCACCATTGAGGGCATCATTTATGTG CTGGATCCAGGGTTCTGTAAGCAGAAGAGCTACAACCCCCGCACAGGCATGGAATCGCTC ACTGTCACACCCTGCAGCAAGGTCAGCCTGGGGATGCATGGGAGTGGGGGAGGTGGAGTT GGCCCACAGAGAAGGTCCAACTCAGAAGCAGGGTGGGGGCTTCCTAGGGAACCGGGATGA GCAGTTTGCATCCTTCCAGATTTCTTGCATAAATACTGCCTTTTTCTTTTCCCTGACCAA ATTGTCAGCCAGCCTGTTCCCCTTTCTTTCCAGGCCTCAGCCAATCAGCGAGCTGGCAGG GCAGGTCGGGTGGCTGCAGGGAAGTGCTTCCGCCTGTATACCGCCTGGGCCTATCAGCAC GAGCTTGAGGAAACCACAGTGCCTGAGATCCAGAGGACCAGCTTGGGCAATGTCGTGTTG CTGCTCAAGAGCTTAGGTGATTGGGCTACCTGAGAGAGGAGGGAGGGGCTGGAGTCACTG TCCTTTGAAGGGACTCTGTTCCATCCATCACACCTCTTTCTAGGGATCCATGACCTAATG CACTTTGATTTCCTGGACCCTCCACCATATGAGACACTGCTGCTGGCTTTGGAGCAGCTG TATGCTCTGGGAGCCCTCAACCACCTTGGGGAGCTCACCACGGTGAGTCGGGGGACAGCA TGGGTGGAGGCAGGATGATAGGGGTCAGGATGGCTCCAGGGACCCCTGTAGTAGTAGCGG GAAACCTGAGGGAGGACTGGGCTCAACTCTCTCTCTCTTCTCCTTAGTCTGGTCGAAAGA TGGCAGAGCTGCCGGTGGACCCCATGCTGTCCAAAATGATCTTAGCCTCTGAGAAGTAAG CCCTCGCCTCCACCTGGGCCCCCAGCACACAAACAGGCCAGGCCTCCTCTGTCTCCAGGG TCCCCTTTGTCTGTCTTTTTCTGTTCATCATACTATCCCTTAACACATAATAAAGTATTA GATAACTCTGATTGCCCCCTTTTGAGGCCCACAAGGGTAAGACACTTGATCCTATCCTTG ATTCCACTGCGCCCGGCCCCTTGAGGAACTTACTTGTTCCTAAGGTTTCCAACTAGAACA TTTAGATGTAGCTGTGGAGGGATGACCTTTAAATGCCATTCCTCTGCTGTCAGAGATCTT TTCCAAATGCACATAGTGAATGCACACTTTCTGCAGAAGCCTCAGAATTCCCCGGTGTTT CCTGCTCCTGCCTCCATGGATGTCCCTCCTTTGTGACTGTGTTTCATCTATGGCCCCTAC TTCCTTGACCCCCAAGCTGCTGCCAGAATCTATCTGCTGGCTGCTTTGTAGCCATTATGC CAACCAGCCTTCCCCACATGAGGAAACATCCATCACACAGTGATCACTCCCCACTCCACC ATATCTGTTCCTATGTGTCTTGCTTTGAACTCATGCTTTCCCCTTCCTGTCCCAGGTACA GCTGTTCAGAGGAGATCCTGACAGTGGCTGCCATGCTCTCTGTCAACAACTCCATCTTCT ACCGACCAAAGGACAAGGTCGTCCATGCTGACAATGCCCGTGTCAACTTCTTTCTCCCTG GCGGTGACCACCTGGTTCTGCTAAATGTTTACACACAGGTCACTGGGCTTGGGTGAGTGG GAATGAGAGACACTGGGGGACTTTAGTCCTGCTGTATACTTAATTATCTCTCCTTTCTTT TTAACTGTCTTCCCAGTGGGCTGAGAGTGGTTACTCTTCCCAGTGGTGCTATGAGAACTT TGTACAGTTCAGATCGATGCGCCGAGCCCGGGATGTGCGGGAACAGCTGGAAGGGCTCTT GGAACGTGTGGAAGTTGGTCTCAGTTCCTGCCAGGGGGACTATATCCGTGTACGCAAGGT CAGCATTTCTTCAGCCTCCTGCTTTCCACCCCCAGTACCTTCCCAGGAGCAAGCTTCTCT GGGGGCATGCAGCATTTCCTCCAGCGTGAGAGCATGCCCTCTTCCCCTTGTGTATGACGT GTCCTCCCAGGGCCCTTTCTTCCCCAGACCACTGAAGGTTCATTCCTGGGAAGTTCTTCA TGCATTCCTTACCTCTCTAGTTTTCCTGAAGCCTGAACTAAAAAGGTAGTGCATTCTTAG GGTCCCCAGATGTCTGCCTTTTCCATTGATTTTCTTTCCTGCCCGCTCCTTAGGCCATCA CTGCTGGTTACTTTTACCACACGGCACGGTTGACTCGGAGTGGCTACCGCACAGTGAAAC AGCAGCAGACAGTCTTCATTCATCCCAACTCCTCCCTCTTTGAGCAACAGCCACGCTGGC TGCTCTACCACGAACTTGTCTTGACCACCAAAGAGTTCATGAGACAGGTGAGGAGAACAT CCTGTGCCCACGCAGGTGGAGACTATGTAGAGAGATGGTGTCCTGGCAAGCTAAGAACCC AGGTTCAAGTTGCTGGGACTGGTACAGAAAGAGGAAGGTAGGGTAAAATAGAAAGACATC CTTTGTTTTTTTTTGTTTTTTTTGAGACGGAGTCTCACTCTGTTGTCCAGGCTGGAGTGC AGTGGCGCAATCTAGCCTCACTGCAACCTCTGCCTCTGGGGTTCAAGAGATTCTCATGCC TCAGCCTCCCAAGTAGCTGAGATTACAGGCGCAAGCCTCCAGGCCTGGCTAATTTTTGTT ATTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGTCTCAAATGCCTGCCTCG GCCTCCCAAAGTGCAGGGATTACAGGTGTGAGCCACCATGCCCAGCCCAAAGACATCCTT TCTAACAGGTGTGTCAGCATCTTCCAAGATCTGAGAACTAGACACTTATTCAATAAATAT TTGAATGGCTACTGTATAGGTGCTGGGGCTATAATGAACAAAGCAGTCTCTGGTCTCACA GAGTATAGTCTTTATGTTCTAGGCTTTTCTTTTTTTTGAGAGAGTTCCGTGCTGTTGTAG CCCAGGCTGGAGTGCAGTGGCACCATCTCAGCTCATGCAACCTCCGCCTTCGGTTTCAAG TGATTCCCCTGCCTCAGCCTCCAGTGTAGCTGGGATTACAGGTGCCCACCACCACGCCCA GCTAATTTTATATTTTTAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTGATCTCGAA CTCCTGACCTCATGATCCGCCTGCCACGGCCTCCCAAAGTGTTGGGATTACAGGTGTGAG CCACTGTGCCTGGCATGTTGTTCTAGACTTTTCTTGGGAATAGCTTATTTGGTATCTTGA ATAACATACAGAGGTGTATCTGCCCTTTGGGTATATAATAATAGAGCCAGGCACCTTTAC ACCTAGCCCTGCAGTCAAAGAGGAAAGATAACTTTTGACCATACACATAAGGATCTAGGT TGGGGCTGGGCATAGTGGCTCATTTTTGTAAACCATCCCAGCACTTTGGGAGGCCAAGGC AGGATCCTAGCACTTTGGGAGGCCAAGATCAGCCCAGGCAACATAGTGAGACCCCAACTA TACAAAAAATTAATGGTGCACTGTGATGTGTGCCTGTAGTCTCAGCTACTTGGGAGGCTG AGGCAGTAGGACTGCTTTGAGCCATGATACGCCACTGCAGTCCAGCCTGGGCAATAGAGC AAGACTCTGTTTCAATTTAAGAAAAAAAAATAACAACAACAAAAGATCTATGTTGGAAAG AAGGGAACTCCATTGATCTTTTCTCTCTCCTAGGTACTGGAGATTGAGAGCAGTTGGCTT CTGGAGGTGGCTCCCCATTATTATAAGGCCAAGGAGCTAGAAGATCCCCATGCTAAGAAA ATGCCCAAAAAAATAGGCAAAACACGAGAAGAGCTAGGGTAAGAGAAGGACGTAAACAGA ACCTGACACCAGCTCCTTTTCCTTCTATACATTATTTAATACCTATTAAATAAAATTATT TTTGGAATAAAGCTTGTGGGAACATTTGGGATCTAGAGAAAGTGA OMIM ID 603405