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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84515
Official gene symbolMCM8
Full nameminichromosome maintenance complex component 8
Aliases,C20orf154,MGC119522,MGC119523,MGC12866,MGC4816,REC,dJ967N21.5,
Gene summaryThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p12.3
Gene position5931298 - 5975833  Map Viewer
Gene orientationplus
Gene size44536 bp
Gene sequence
OMIM ID608187