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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL43 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 84545 Official gene symbol MRPL43 Full name mitochondrial ribosomal protein L43 Aliases ,MGC17989,MGC48892,bMRP36a, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24.31 Gene position 102747272 - 102737579  Map Viewer Gene orientation minus Gene size 9694 bp Gene sequence >MRPL43:complement(53542043..53551736):Length=9694 CCGGAAGCCTCGAGGTTTAGTCCCGCCCCCCTCTCCTCGCTGCTTAGGCTCCGCGGCCTC CAAGCTGTAGCTATGACGGCGCGCGGGACTCCGAGCCGCTTCTTGGCCAGCGTTCTCCAC AACGGACTGGGTCGCTATGTGCAGCAGCTGCAGCGTCTGAGCTTCAGCGTCAGCCGCGAC GGCGCCTCGTCTCGCGGCGCCAGGTGAGCCAAGGGAAGTGCGCAGGCGCGGGTCGGGGTG GGTGTGGAGGTGGCAACGACTCCCCGGGTAGGTCGCCCCCAGTCAGGGGTCATACTGCTC ACTGTCCCGGGTCGCTTAGGGAGTTCGTGGAGCGGGAGGTGATCGACTTCGCCCGACGGA ATCCAGGGGTCGTAATATATGTAAACTCGCGTCCGTGCTGCGTGCCCAGAGTAGTGGCCG AATACCGTGAGTGGGGCCGGGCTCGGGCTGGAGGGCGGGATCAGGGGCTCGACCCGCTAT CCTCCTTCTCGCTTGGTCGCACCGGCCAGCTTCCACCCACTCTCACCCCTCTTCTGCCAG TTAACGGGGCTGTGCGCGAGGAGAGCATCCACTGCAAGTCGGTCGAGGAGATCTCGACGC TGGTGCAGAAGCTGGCCGACCAGTCGGGCTTGGACGTGATCCGCATCCGCAAGCCCTTCC ACACCGACAACCCTAGCATCCAGGGCCAGTGGCACCCCTTCACCAACAAGCCGACCACGT TCCGCGGGCTACGCCCCCGAGAGGTTCAGGATCCTGCCCCAGCCCAGGTGCAAGCACAGT GAAGAGTTGCCCCACCAACTGCAGCCCCAGGCTTTGGACTGTTACTCCGGTAAAGGTGGT TCTTCCCCTTTGGGATTCCAAGCCCAGGCAAATGGAACCCATCAATGGGCAAGTTGACAG AGGTTCTGCTTGGGATAATGAAGAGCTGCCTGTTTCTTTCCAGTGCCTGCTTCTGGGGGC AGTGACCTTGTGAACCACTCATTTTTATGCAAGTGGCATCCCTAAAACCTGAGATGAGGA AGACTTCAAGGGTTTTACAGGGCCCTTGTTTTTTAAATCCAAATTGATAATAATGATCTC AAAACACAGTGAGAGGTCTGAAGGCTGGCTTCTGAAGAATCCCTGATGTCTTATTGGAAC AACCACTGAGCTACGGAGAGCTCTGCTGTGATGGGCTAGGCACTTTATATCTGTGTGAAT ACAGATTTATAAAACAGGTTAATAAACTTATCCAAGGTCACATTTCAGGTCTGTCTTCAA AATGTGTGCATATGTTAAGCACAAGCCTCAGTTTTCATTATTTTAAAACTAGACGCAGAA CATATAACAACTGTCAGGTGGTTAGTATCAAAGGCCAAGTGATTAATCTAGGCCTGACCC CTGAAAGGGAGAGGGGAGTGATTCTCAGACCAAGTCCTGGCTGACAAGCTTTCTCTGGTC TTAGCTATACATCTCCTTCCCCCCACGTCCCTCTTTGTGCAGAAATAAAATCCATGTCCC TTGAGCCAGCTGGTGGGGGGTGCTGAGAACCTTGGGGAAGGGCAGGAAGGCTGATATTAA TGAGTATTTTCTAATCTTAGTTTAAAAAGGGGGGATGGTGGGGAAATGAGAGGCAGGAAA TGAAAATCTAGAAACCCCTGTAAGAATTCTTGAACTGTTGTCATTTTCTTGTCATGCCCT AACACCATGATCAATGAATAGTGTGAACCTTACTAAAGAGGCCTGTGTGCCTGCCAAGGA GTCAGGATGGAAGCGGAGGATCCCAATTTCCTCTGCAAATAGTTGTATTGGGGAGCAGAG CCAATCCTGGAGGCAGATATCACCTTCTGTATAGGCTCAGGAGCCTGTCCCCTGGTGATC AGGGGTGGGCGCATCTAGATGAAGCAGACTAGTCATAGCTGTGGGGAAAAAGGGTGTTTA TTAACCAACGGCAGGGGGAGGAGCTGAGCCCAGGCTCCCCACTCTGTCACATGCCTGTTC CACCCACCTGGTTGTAAGTGGGGGCATTCCTAAAGAAGTGTAGCCATTCTCACAATAAAT ACATTCATTGTGGGGTGGAGGTGGGAGAGGTTGGGTGAAGGGCAGTAAAAACCCGTGGGA TTCCACGTTCTCAGCTACAAAAATAACAGTCATCCTCACCCGAGGGGAATGGGGGAGCTC AGTCAGAATTGATTGTCCCATATAGGCCTAGAGACTTCAGAGGCCCCTGGCCCCTGAAAG TGCCCCGGTGAGGTAGGACAGGGGTAGGAGCTAAGCGTCCAAACTCCCAGCCTCTGCCCT TTGCATAGTTCCAAGAATGGGCTTCATGTGCCAGTTGAGACATCAGATTTCTCCTCCCTT TCCCTGCTGTAGTCTAGAGGAAGCAAATGCTTGATTCCCCCAAAAGAGAGGCTGGCTCAT TGAGTGCAGTGTTGGTCATCCATCCTAGGCAAGGGCCTGTGAGGACAGTTAAATGGGAGG GGGATCTCCCTCTGAAATGTCCACGGACTAAACCCAACAGACAGGTCCAAGACAGCAAGG GAGGCTCAGAGGTGCATGTGAGTGGAAATGTAAGCACATGTGTGATACAGGTGTGTGTTA CCACATGTGCATGGGGATGGGACATGCCTGGAGCTCTGTCTCTCATACTCTTGAGAATGA CCAAGGAGAGTGGGGAGGCTGATTCACAAGGGCCACACAGGAAGGGAGAGGAGGGGAGTG ATGCAGTCTTACCTCCCCAGGCTGGCCCGTTCCCAAGCTCTTGACAAAGAGGTCACCACA TGGGGCTGGGGAAGAGGACCAGATAGGATGTGGCAATTGGGAGGGTACCCCAAGTCCAGA AGCAGGGATGAAACAAGAATGCACCAGGAGAAGGTGAGGGTGGGGGCACTGCAGCCCAGC CGATAAACATTCTTCCATGTGTGCATGTGAATGTACGCAGGGCTTAGGTGGCTGGCAGAG GTCTTGTCTGGTTTCAGGACCATCCAGCACACAGGGCCATGCAGAGGGTGGTGACATTGA GCCCATATGGACCTGCAGAGCCCTGCCTGGGAGAAAGAGAAAGGGTTTGGGCAGATGAAT GGAACAGGAGGATGGAGTCCTCACCTATAAGTGTTTAGGTTAGGGGATAGGAACTGGCTC TGGGTCTGCAGGGCACCTGATCCTGAGGGAGCACCTACCTCTGAGGAGCACCGATGGGCC TGGGCTGCTCACATGTGGGTCTGTGGAGACTGAGGAGGGGGCTTTGGCTGGGCCTGACTG GCCAGCCCTACAGGGACATCAAAAAGTTGGGAGAAGGGTATGGAGTGGGGGTAATGAAGG GAGGGTGGCTGTGTTAGGGAGGCAGTGGCCCAGCCTGGGACAGATAGGCTGGCTTGGAAG AGCATTTGTTCTGGGAGGCTGGGCTCAGACAGAGCTCTCATCTAGCTGCTCCACGAGCTG CGTGTGCTTCCTTTTTTCCAGGATGCGGCTGAGTTCCTCGGCGAAGGAGCAGGGCCCTGC TGGTACTCCATTGTTGCTCTGCCTCAGAAGCACATAGCTATTGCCATTCATCCTCCGCAG CCGGCTGGGCAGTGCCACCAAGCCATTGGTCAGCTCAGCCGGTGGCGGTGGGGGCGGTGG GGGTGGTGGGGCTGGGGCTCCCTCCCCAGGGATGATCTGGAGACAGCTGCCCTCCAGGCC CCCAGCCCCCTCATCATCACCCTCATCTTCCTCTCCAGGACACTGGCCTGAGACTGTCTG CAGTTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCAGTGAGTATTTCCGTCGGCG CCCTCGTCTGCCTTCCCGCAGACAGGCCACATAGAGGAGGGAGGAGGCCAGGATGAGGCA GAGGCCACCAAGCGCGGCAATGGCTAGCACATAGAGCAGTCTCACATCAGGTGCCAGCTG TGCCCCAGGTGTGGCAGGGGCTTTTGGAGCTGGGGCAGGAGTGGCTGGCCGGACTGTGAG ACTATAGGAGGCCAGCAGGGTGCGGAGGCCATTTTCCTCGGCATAGCAGCCATAGTTGCC ACTGTGCTCAGGCTGTGCATCTGTAACCAGCAGCCCGTCCACGCCCACACGGTAGCCACC CTGCCCATCGCTCAGGCCCATGCTCCCATTGAGTAGCCACAAGGCCCGGGCCAGGTTGGA TGGCTGGTCACAGGGCAGGAGGACATCATCACCCCGGAGCACAGAGCGGGTCTTCAGTGG TGGTGGTGGCCCTGTGGGGTTTGGGGGAGAGGTCAGTACCAGCCCGTCCCAGGAAGGGAT TAGAGATGGCAAGCCAGACTGTTCACTGCCAAGTCCCTGGCACCAAGCACAGAACCCAGA ATCACAGTGACAGCTGACCCAGGCTCTGTGCTCATGCTTCCACAGAAGGTTCACGTTGGC CCTTCCCAGGAAGCAGGCAGTGCCTTGGGCCCTTTTCCATTCTCTCTCCATGCTCTCATC CTCTCCTGTGGTTTCAATTTCTGCCATCTGCCAGTAACTCCTAATCTCTACCTCAGACTT CTCTCCTGAGTGCCAGACTCGGATATCTACCATGTGCTGGGCATCTCCACATGAGGTCTC TTGGACACCTCAAAACCAAAGCTTTTCTCCCCAACGACACCAAGTCCTTTCCTTGAATCG CCACCACTGTGAATGGCACCACCAGCCACACAGTTGCTTAAGTCAGAAACCTGGGAGTCT CCCTTCTCTTTCTTGCTCGCCTTTTTGTTTTGTTTTGTTTTTTTGAGACGGAGTCTCATT CTGTCGCCTAGGCTGGAGTGCAGTGACGTGATCTCAGCTCACTGCAACCTCCACCTCCCT GGTTCACGCGATTATCTTGCCTCTGGCTCCTGAGTAGCTGGGATTACAGGCATATGCCAC CATGCCCAGCTAGTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCT TGTCTCGAACTCCTGACCTCAAGTGATCCACTCGCCTTGGCCTCCCAAAGTGCTGGATTA TAGGCATGAGCCACCGTGCCCGGCCCTTCTTCACGTTTGTATCTAACTGTCACTAAGATT CTGTTTCTGGCATCTATCTTAGACCTGTTGATTTCTCTCCTTCCATGACTCCTGGCCCAC TCTGGCCCCATGTAATCCATTCTTCATGAGAGGTATTTTAAAAACACAAATCTGATCATG CCACTCTCCAGCCTAAAACTCTTCAGAGGTTTCCTATTGCTTTTCGGATAAAGACCAAAA TCTTCAACATGGCCTTTGCCCACTTGTCCAGCCTATTCTCCTGTCACTCAAATGTGCCAG CCTCCCTCTGCCTGCTGCTCCCTCTGCTTGCATGTCACCCCATTACCCCATGTCCTCTGC TTGCCTGGCTAACTTGTGGGAGATAGCATAGTATAGTGACCAGAAGCACAAAGTCAAATC AGACTGCTTGGGGTCAGGTTTGAATTCTTTTTTCTTTCTTTTTTTTTTTTTTTGAGATGA GATGAGGTCTCACTCTGTTATCCAGGCTGGAGTGCAATGGTGTGATCTTGGCTCACTGCA ACCTCTGCCTCCCAGGCTCAAGTGATCCTCCCACCTCAGCTTTCCAAGTAGCTGGGATTA CAGACATGTGCCACCACACCCGGCTAATTTTTGTATTTTTTGTAGAGATGGGGTTTTGCC ATGTTGCCCAGGCTGGTCTCCAATTCCTGAGCTCAAGCAATCCACCTACCTCAGCCTCCC GAAGTGCTGGGATTACAGGCGTGAGCCACTGTACTCAGCCAGGTTTGAATTCTGGTCCAG TTTCTTAATAGCTGAATAAGTTTGAGCAATTTACTTACACTCCCTGGGCTTCAGAGAGGT CCCTCATGGGGATAATAATAATGGCACCTTTCTCATAAGAATGCTGTGACAGTAGATGAC ATCATGCATAGAAGTATTTAGATCAGTGTCTGGCACACAGTAAATACTTAATACATCTTA GCTGTGATGATTAACTTTTGTTCTTTCTTCAGATATCAGTTCAGTCATCCGATCTTCCTT GGGGAAATACCCATTACCGTCCTGAACCCTTGTCATCCACTACTTGGCTATAAGCTCCAG AAGTGACAAGACACTTCACATCTTAAATATGTTTCCTAGTTTATAATTCATTTGGGCAGT AAATGTTTGTTGAGCACTTACTCTGTGCCAGGCTCTGTGTTTGAGTCATCCTTACCAAAT GTACATAGCCACAGCCACTCAGATACAAACATATACGTACACATGGCAGTAAATGGCAAA GAGGACAGTCTGCGTAGCTAGACCCACACTCATATGAGTCACTTACCTGTATCCCTGCTG CTCTCACAGCCTCGATTTCCTCTCTCTATGTCCTGTATCAGTGCTGTCCTGGGACAGAAG ATCAGGTTTTATGAACAAGGGGAACTGGGTTTCAGTTTCCCAGTGAAAGGGTAGATAGGT CTGTTACTAATAACTAGCCCCTGCACTCCCCCAGTAGCTATCAGGCCTTCCTCCTCCACT CAGACCACATGTGACTGTCACCCCCCACCACTTCCCACCTGCTTCCCTGGGACCTGTTGG CTATGGTGGTGGCTGCTGCGCAGGCATGGGTGCCAGGGTCCCAGCCACAGTAGGGGTCTC GGGCCAAGATGCAGTCATAGCAGGATCGGTAGCGGGAGCAGCTGGAGAGTGGTAGCTGGA TGACTCCGCTAGGAGCCCCCACATAGAGGCTGTGCTGGGAGCCAGATAGGACAGTTGGTC GGCAGCGTCCCCACTCATACAGATACACAGCCTCTGCCCAACCTCCCCACTCCCTCTTCC TATTTCAGCAAGGCTATATTAAGGGTCACAGAGAAGGGCTACCTGCAATAGAGAGATGAC TAGATTTTCCACAGACTGGGACTCCCTGAACACTTGTGTCTCTTCAATAATGTGCATCCC AGAGCCCAGGACTACGGCCTTGTGGATCCAGCCATCAGCTGGTATGGAAAGAGCAGAGAG TTAGACCCCAACTATGGGATCTGCTCTCAGCACCCTGCAAGAGGCCTAATACGAACAGCT CAGGAGTCCTGAGGTCCAGAACAAGGACTCAGCCAGGAGCAGTGGACCCTCAGGACACTG GGAACTCCAGACTAGTCATGGCAGGAATTAATGGATTCAGAAGCATTAGTGATCAGGGCC AACAGGGATCAGGGATTGGGATCAGAAGCACCTGTGCCCAGAAAGAGCAGGTCATAGGTA GGTCCAGCAGGCGTGGTGACAGGTGTCCCTGTAAGGTGTGTGTAGCGTATGTTGCGCTTG AGCAGCAGGGGCCGTCCACGTGTGGGCACAACGGGCCGAGCCATCAGTGGGTGCAACTTT ACAAAGTCCAGGACCAGGGATGGCAAGTCTTGGGATGAATTGTAGCCTTGGCTGCGCAAT GAATCTGTGATACACTGGCGTGGGGGACGAAGGTGGTGAACCTCGGGACTCCACCACCTG CCTGCCCTCTCCACAAGGCCAGACCCTTTGACCCTTCCCTGGGCTCTGTCTACTCAGCAC TGGCCCCAGGCCTGGGCACTCACCGAGCCAGGCCGGGGCTCAGGCACCCCACCCTCATAG CGACCCCAGCGCCGGGAACCATCCTGGTATTCCATATAGGGTCCTGCAAAGACAGCCTGG ATCTCTGCCAGGTCATAGCGGCAGATGGCTGAGGCCTCCAGGGTCTTCCTAGAATGGGAC ATAGGGCAAGGGGGGTGAGTTACATGGAGTCAAGCCTGCCCCCCAACTCGTGCTCAGCCT GAAGCTCACTGTTACCCTGGCCAACCCCAGCTATAGTCCCACAGGGCCTCTCCTGTGAGT CAGTGGACCACTGCATTCATTCTCTGGCTCTAGCCTAGCTTGATGTGCTTAAAATTCTCA CTTTGCCAGCACTTTGAGAGGCCGAGGCGAGCAGATCACGAGGTCAAGAGATCGAGACCA TCCTGGGCAACACAGTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCGTGG TGGCACACGCCTATAGTCCCAGCTACTCGGGAGGCCGAGGCAGGATAATCACTTGAACCC GGGAGGCGGAGATTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGCAACAGAG CAAGACTCCCTCTTAAAAAAAAAAAAAAATTCTCACTTTGCAGCCAGACCTCCCCACAGT GGATCCTATCTCATCCTCATTGACCTCTGCTCCAGCCCCTATGCTGTCCGCAGTTTCTTG CCTCCCGATTGTCCCTGCACTGACCACTGTGTGCTCAGCGTGAAGGCTGCATAGAAGTGT GTACGGCTTGAGGTTTCAGCATCCAGGCTGCAGACCCCACGCAGTGTCTCATACAGTGGA ATGTGGCAGATGAGACGGGCTTTCAGGAAGGAAGTCCACTTCTTCTGCAGGATCTTCTTC CCTCCCAGGTCTCCCTGGGGAGGTAGAGGCACGGGATAAGGGGCCAGGGTCAGAGGTCCA GCCTCTATACCCGTGCCCCAACGTCAGCCCAATCCACCTTGCAGACACGAGCCACACGGG CCACACGGTGACTGCTGCGGCTCTGAGTGAAGCTGCCAGAGCCCTCCTCAGTGGCACGCT CCGTGAAGAAGTAGTACACCTTGTCATCATCACCCACTGCACTGGCCTTGCTCTCCCGCA CGAGGACGGAGAACACAAACTCCGCATCTGTGGGTCAGGCAGTTTGAGAGGCTTTTGAGA CAGGCTGGGGATTCCTTTCCCTCACTCTGAGGCTGACCCCTCACTTGACAACACACAGGA ATGGAATGGACAGGCTCACCTGGGGATTTGGGGGTGGGGTGGTCAGCTGGCCAAGGGAGT AAAAATGAAGAAATAGTCCCCTACCCCCCATCATCCTGTGCCTCATCCTCCTAACCATTG AGCCAATGCATTGGTGTCTCCTCAGTTCTCAGGGAGTGTGGGTGGCGGCTCCGGCGGATG TCAGGAATGCTCCGGAATTCATACCTAGTGGCTGTGTAGAGGCCTCCATCTGGCGTGGGG ATATTCCAGGCATGAGAGACATGTCATATTCAACAGGGCACATGACATATACATGGTGGC AGGTCCTAGAGATGAGATCCACATCCTAAAAATACCATGTCTGTGATAGGGAAGAAGGCC TGCTCACCAATGATGAGGCCTGTGAAGCCACGGGCTGGGTCATAAGGACACTTCTCCTTC CCCTCCTCGAAGCTGGTTGGCAAGGTGAAGGCCTCAGCATCCTAGGGAACAAGGAACCAG CAGTAAGTGGTTCCGAAGACAGGCAGGGACAGTGGCTCAAAGTCAGATCAGTCTGGGGTC AGGGATCAGCGATCAGGGATAGGGGCAGGTTGTATGGCAGATGCACCTGACAGCAATAAC TTAAGCATCCCCTGAGAATGACCTTATGGCCTCAAAACAATGTATGTTTGGAGTTCCAAA TCTGCAAGTGGCCAACCTAGAGATTCACTCCTTATCTATGAAGAACATCTGAGCCCCTAG CCCATCCTGTGGAACACATGCTGTCCAGGGGATCAAGGCCCTTTGTTTTGGGTTAAATGA AGTTTGCCAGGTGGAGGTGATTAGGGGGAGGATGCTAAGTGAAAATGCTATAAAAACTGC ATGGTTTTTACAAAGGGGAATGGTTCTCCAGTGCAGCCCGCCGCCACTGGAGTGCCCTGT ATGGAAGTCCCCTTAATAAACCATCCGTCTCCTT OMIM ID 611848