Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM63 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84676
Official gene symbolTRIM63
Full nametripartite motif-containing 63
Aliases,FLJ32380,IRF,MURF1,MURF2,RNF28,SMRZ,
Gene summaryThis gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p34-p33
Gene position26394121 - 26377798  Map Viewer
Gene orientationminus
Gene size16324 bp
Gene sequence
OMIM ID606131