Entrez gene ID | | 84676 |
Official gene symbol | | TRIM63 |
Full name | | tripartite motif-containing 63 |
Aliases | | ,FLJ32380,IRF,MURF1,MURF2,RNF28,SMRZ, |
Gene summary | | This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p34-p33 |
Gene position | | 26394121 - 26377798 Map Viewer |
Gene orientation | | minus |
Gene size | | 16324 bp |
Gene sequence |
| |
OMIM ID | | 606131 |