Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LOXL3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 84695 Official gene symbol LOXL3 Full name lysyl oxidase-like 3 Aliases ,LOXL, Gene summary This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq] Location Chromosome: 2   Locus: 2p13 Gene position 74781062 - 74759946  Map Viewer Gene orientation minus Gene size 21117 bp Gene sequence >LOXL3:complement(53581833..53602949):Length=21117 TAGGACTGATCTCCAGGACCAGCACTCTTCTCCCAGCCCTTAGGGTCCTGCTCGGCCAAG GTAGGGGGAGTCACGCTAACCGCAGAGGGAATGAGTAGGGGATGGAGAGGATGTGGAGGG ACCAGGGAAAACGGGTGGTGTGGGATGGAGTCGAGGGGAAGCCACCCAACTGAGAGTTTG ATTCTTGTCAAAGGGCAAGTGAGACAGAGTACACGGAGGAGGCACATACCGGAGGCGGGG GCTACGGGTGTTCGAACAGGGCCGCCAGGAGCGCCCTAAGGGAGGGGGCTCCTCCGGGAG GCGCTGCCCCTGGGTCCCCAACCCAGAACAAAGCTGCCTTGTTGGATTGATTGTTTGGGT TGGGGGAAGCATGTTGACGGGGGCTTGCTGTAGAGGGGCTGTTCTCAGCCCTAGGCAGAG AAGGCCTTGGCTGAGGAGCCATAGCGCCTGGCCTCCCGTTGCCCGGTGACAGGGATGGTG GTGTTGGCAGGAGGCTGGGACAACCCTACCCCATCCCCCGCCCAGCCTTGAGGCCTGGCC CTCCTGGGCCTCTTGACCCTGCAGGGCATCTGAGAGCCTGCGTGTTGGGGAGGGCGTGCA GCAGGTTCTCCAGGCGAGCTTTGGTGCCAGCCTTCCCTGCCTGGGAATCTGCTGGGTTAG GACTCTGGGCTCCCATTCAGGGGATCTGTGATCCCAGGGCCGCCTAGGGCCCCTTACGTG CCTCTCTGCACAATCAGTACAGCTGTCTGTCCTCCCTCTGAGTAAATGGGGTCATCTGGA TCCCTCCCACGTCCGCCCCTTGGCTCTTGTCAATCCCTCTCCTTCTCACCCGCGGTGTGC TTGGTTCCCCTATACTGAGTGCTTAGTTCTTTGCCTATCACTTTCTATCCGTTGTCTCTC TCCTCTGTGTCTTTCTGGTTTTCTCTCTCTCATTCCCACAGTCTCCCTTCCTCTCACATC CTGTCTGTCTGGGTCTTCCTCTCTCTCTACGTGTCTCTTGCTCAGTCTCTATCTCTTTTT ATTGACCCTTCTCTGACTCTCGATCTCTCATAGTTGTCTCTTATCTCTGGGTCTCTCAGG CTGTGCCTCTATGACCTGTGCCTCAGCCCTTATTTAATGTGTTTCTCTCCCTGTCTCTTG GTCCCTGGGGCTCTTTCTCTCCTGTTGTCTCTCGCTGTCTCTGTCTTACTCAGTGTCTGT TTTTCTTTCGTGACTTCTCCCTCTCTTTCTGACTCTGGGCCCCACTCAATCTGTTTCTCT CACGCACACTTTGTCTCTGGGGCACCCAGGCCTTCCCTGCCATGCGACCTGTCAGTGTCT GGCAGTGGAGCCCCTGGGGGCTGCTGCTGTGCCTGCTGTGCAGTTCGTGCTTGGGGTCTC CGTCCCCTTCCACGGGCCCTGAGAAGAAGGCCGGGAGCCAGGGGCTTCGGTTCCGGCTGG CTGGCTTCCCCAGGAAGCCCTACGAGGGCCGCGTGGAGATACAGCGAGCTGGTGAATGGG GCACCATCTGCGATGATGACTTCACGCTGCAGGCTGCCCACATCCTCTGCCGGGAGCTGG GCTTCACAGAGGCCACAGGCTGGACCCACAGTGCCAAATATGGCCCTGGAACAGGTGAGC AATGATCCAGGCATATCCTAGATATTTCCTATGTGTGGCCAAAGTGCAGGGAAAGGGAAC ACGAGGATGGCACAGCCATAGGGACACACGACACCAAGAACAGCCAGCATTGAGTAAATC CATGGATGACAAACCAAGCAACATAGTTACTTCCCAGAGCTGTGTGACCTTAGGCTAGTC AGTGCTTTCTCTGAGCCTCAGATGCCCTGTATGCAAAATGACTAGATGATGTCTAAGTTC TTTTCTGCTGCAAAAGTATGATCCTACAAAGCCATCCACAAAACAGCCCAGATACAGGTG AGCCCTGTACAAATAAAGTACAGTTAGTCTCATGGGACGCTAAGAGCAGGTAAATGATAT CTGGATGTCCCAAAGTCACAAGGGGTCACAGACACTGCAGCTAACAAAATCAGGTTATGG GCCAGAGCTAAAACTAACAAGGTGGTACTGTCTAAGGACAAGTATAAAATCTAGGACAAG TATGAGTGTGGGTGGTGGAGGCTTAAGAGCAGTTCCCTAGGTGAGGCCTAGGACTGTGCC CATGGTATGAACCCACAGTGGGAATGATGGACAGAAGCAGGTGCAACCTGCAGCTGATTC CCCAGTTCCCACTGGCTAGACCACCTGTGGAATTAAGTGTCATTTGTAGATGCTGTGTTT TAAGAGGGACAGTAGAAAATGGAAATACTTTCAGAGGAGAGCTGCCTAGATGTGAAAGAT TCAGAAGCCAAGTTTCAAGGAGGAATTGCTGAAGAATCAGGGGATTGATATGGAAAGTAA AAACCTTGCATAGCAATGGCGTAATGGTTGTTTTTAAATATGGGAAGGACAGTCGTGTGG CTGAAGGATTTTTCTGGTTGGCACCAAAGGAATGAATCAGATGTGGTAGGGGAAAGTCAT GAAGAGTCACAAGGACTTTGATGGTTACACAGTCTGGTGGGGCAGGAGCTAGGTGTCTCC GCAACAACTGGGTAAGTCCTGTTGGGATGTGAATGAGATGTCCTTGAACATTGGCTAGGA CAGATGACCTTTGAGGCTGCGCCCAATTCTGAGAGGAAGCCAGTGATACTCCACAGGGTT CAGGCCGGGCTCAGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCTGAGGTGGGTG GATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTTGAAACCCTGTCTCT ACTACAAATACAAAAATTAGCCAGGTATGGTGGCACATGCTTGTAGCCCCAGCTACTTGG GAGGCTAAGGCAGGAGAATTGCTTGAACCTGGGAGACAGAGGTTGCAGTGAGCTGAGATC ATGCCACTGCATTTCAGCCTAGGCAACAGGGCAAGACTTCGTTTCAAAAAAAAAAAAAAA ACAGGTTTCAGACAGAGAGAAGAACAAGGGGCTATATGGCAGCACAGACAGGGCGGGCAC AAGAGAGAATGCAAGGATGTGAAGAAAGGATCTTAGACATCCAAGCCTCACAGATAGATC AAACTCCTAAGCCCCCACGTATTGGCTTTATGGTCTTAAGCAAGTTGCTCAGCTTCTCTA AACCCCAGTTTCTTTATATAAAACAGTGTTCTGGCAGCTCTGTTCTAAGAATGATCACAT ATGTGCACACCATGGCAGAGCACCTGGCACACAGTAGGTACCTGATTAATTGTAGCTATC AATGAATGGGTAGAGACTGATCAGAACTTCAGGGTTGATTCTTGGTTTTTTATTCACCGT ATCAGGTTCTTGAGTATCCCCAGATCACACCAATTTTCCCTCAATCTTATGCCCCCTTCC TATTCCCTGCCAGGGTCCCCTGTCCCGTCTCCACCCCTTATCATACCAGAAAGATGGGAT CATCATGGCCAAGTGGGAGGCCTCAGCACTCACTCTTCCCTACATCCCCATTACTCCCCC ATCCTCCCTCCCCAAGCTTCTCTGTCCCTTCATCTCCCCTTCCACAGGCCGCATCTGGCT GGACAACTTGAGCTGCAGTGGGACCGAGCAGAGTGTGACTGAATGTGCCTCCCGGGGCTG GGGGAACAGTGACTGTACGCACGATGAGGATGCTGGGGTCATCTGCAAAGACCAGCGCCT CCCTGGCTTCTCGGACTCCAATGTCATTGAGGTCTGCATTTCCTAGACATACACACACAC ACTACCCAGGATAGCCGAGAGTACTGTGGGGTGGTTAGCGGAGACATTAGAAGGTAGTTA CCCCTGGGGGATCATTTGGATTGGTGGGAGACTTGGAAAAGCAAATGATAGAGCTCCCAG ATGCTGTAAAATCCAACAGGTTTTTAGCATTCACATTCAAGGGGCTAAACCTGGCATGAG CCTCTCCAGCTTCATCCCTAGTCACCCCTGGGGCACCTGGTGCTCTCCTTCTCCTCAAAT GTTCCTGCTTTCCTGAGACATCTTCCTTCTGACTTTCTCCTCCTTCAAAGCCATTTCCTT TTTGAAGTGCTCCCTCCTGCTCCAGGCACAGGGAGGGCCTCCTTCCTAGTGCCCTGAATC CTCTCTGGGAGCACAGCACATCCCACGCGCTGCTGGCTGCAAGAGAGTCCACACCGCGGA CTGCGGCCATCGTGGCCGCTCTCTCAGCGCCGCCTCGGGCCCATCCCGCCACTGGGTTTA CAGCAGGCACACCAAGCAGGGTTCCTTAAGGGCGGCGGGACACATGAAAGGTGCCACTGG GATTCTTTCCCTGCTTGTGGCCCCGCCCCCAGGTAGAGCATCACCTGCAAGTGGAGGAGG TGCGAATTCGACCCGCCGTTGGGTGGGGCAGACGACCCCTGCCCGTGACGGAGGGGCTGG TGGAAGTCAGGCTTCCTGACGGCTGGTCGCAAGTGTGCGACAAAGGCTGGAGCGCCCACA ACAGCCACGTGGTCTGCGGGATGCTGGGCTTCCCCAGCGAAAAGAGGGTCAACGCGGCCT TCTACAGGTGAGGGGCCGCGGGCGCCGGGCGGAGCAGGCCGGGATTGGGGTGCTCCCTGA TGAATAGCCTTGGGAGACATCTGAGCAGGTCCGGGGCACGGGAGGACCCGGGGGTCGGGA CGCGCGGGAAAATATGGAGGCCGTTGCAAAGCTGGAGAGTTGGGAAATCTTGTGGGACCA CGAAAGGTGCCCCAAGGGAGTACCTGAAATGGGGACCAGCGAGGCTCCCGCTCTCTCGTG GCCGACGCCTGGGCGGGCAGGCGGATTCCTCGGCCCCGGGGCGCGCGCCGGCCTCGCGAG GCCACTCCCAGGCGCGGGGGCGATTCCAGCGCTGGCGCTGCCGGCCAGCGATTTCCGAGT TCAGTAAGGACGCGGCCGCCCCTGGGAGGCGGCGCCTGGGTGTGTCCCGCGCAGGCTGGG CGCCCAGGGTCCGGGGGCCCGGGGACGGCGGCGCGCGATGGCCGAAGGGCGCCAGGAGAG ACCGCGCCAGTCTCTCTGCCCGGGCCGCCCCGGGGCGGGGCGCGTATGTGAACGCTCGAG CCCTCGGGGCTCCTGGAAGTCCTGGAAGTTTCCCAGGATCTCTTTTGGCGAGGCCCAACC TCTCCACCTGCGCTGGAGCCCTGGGGTCCAGTCCGGCTTCCAGGGAAACGCATCACCCTG GAAACTGCCTGTGCTTAACGTCTCCCTTCCCTGGAACATCTACTTTGATCTTTTTGAGAA ACTGCCATTGACAGCCAGGCATTTATTTGGAAATCTTTACACCCTCTCACTGTAATCTAT TTTGCGAGCCAAAAATCCTCCCTTTCTTCAGTGGTTCCCTAGATCAGTATTGCTGAAAGG CCTCTTGATGTCCGGATAGGTTTCCGCGGGCACACTACTTCAGATGGGGTCTGATGCCGC CAGCTACTGTAGAAATCCTCAACCCCGACTGAAGCGTGCTCGGATTACACTGTCTTCCTA CTGCGGCAGCTTCCCACTGCTTATACTGAACTTGTCATCACTTAAAACCAGTTCAGGTCT TCCCTATGCTTCCTACTGATAGAGCAGCCTTTTCCAACCCAGGTATAGGTGACGTTTACC TATTACATTTGTTTTGATACATAATTTAGAAGCCATAAAAAAGCCATGATGATCCCATGA GATTATCTTGAGTCCTGATGTGACTTTCCATCTGTCATTTCCCCTCAGCCTCCTCTGCTG AACAGACATGGCAGCTTTGCCTTCTGGCTTCATCCAAATGGCTAAAAGTTGTTGTGGAAA TGTTTAAAACCAAAGTCTAACTCTTCTTGCAAAATGTTCCTGTAGATTTTCATCAAGCTT CTAATCATCAGCTGTAAAATATGTTCCTTCCACCAACTGGGAAGAAACAGAACACTTCAA TGATGTAACCAACATTTCACCTTATCTATCTATATATTTCTTATCTGTAATGAAATCATG GGAGATTCTGTTAGTTTTTGATAAAATCCAGATATGCTATGTTCACAGCCATTCTCCAGC CTTCCAATTTAGTAATCCTGTCAAAAAAGAAAATCATAGTAGTTTGAGTCTATTTTTACT GAAATCCTTTTAGGTCTCTAAGAATCACCTTATTTTTTCCTAAATGCTTACAAACTTCTA TTTAATAATTTATTCTAGAATATTACTTATGTGTAGATTGAGGAATTGAGGAATCCTTTT TCTCCTTTTTTTTTTTTCTTTTGAAAGTCAGGATATTATCCAGTCTCCAGTCTTTTCTAT ACCTGCTCACACTTTCTTTGCCTTGGCTCTGAGGCTCATCTGAAATGTCTTTCAGTACTG AGGACTTTCGGTACTTTATCTGGCCTGGACACTCAAACCACTTTAAAACAAACGTGCTGT GCCTCTTTACTTTCATCCATCTTGGGGCTGCATTTCCTTCTCTGTGCTGCTTACCTTCCC TAATTTAAACCCCATGTTCTGAAAGATGCGTAGAATTTAGACATTTCCAGTGAAGAAGAT AGCGTGAACAAAGGTGTAGAGATCCACTCACCCAATATTTATTTACTGAGATCTTACTAT GTGCCAGGTACTGTTGTAGACACTACCCGTGGCTCATGCCTATAATCCCAGGACTTTGGG AGGCCACGGTGGAAGCATTATTTGAGCCCAAGAATTCGAGACCAGCCTGGGCAACATAAT GAGACCCTGTCTCTACAGATAATTTTTTAAAAATAAAATTAGCTGAACATGGTGGTGCGT GCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAAGATTGCTTGAGCCCAGGAAGTC AAGGCTGCAGTGAGCTGTGATCATGCCACTACACTGCCTGGGTGGCAGAGCAAGACCCTG TCTCAAAAAATAAATTAACTAAGGCCGGGCACGGTGGCTCACACCTGTAATCCCAGCACT TTGGGAGGTCGAGGCGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACAT GGAGAAACCCCATCTCTACTAAAAATACAAAACTAGCCGGGTGTGGTGGCGCATGACTGT AATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATGGCTTGAACCCGGGAGGCGGAGGTT GCGGTGAGCTGAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCGTC TCAAATAAAAATAAAATAAAAATAAATTAAGTAAGTAAGTAAATAAATAAGTGGTGAAGG AAGGCCTCTTGGAGAAGGCATCATTTGAGAAAAGATTTAAAGGAGGTGAGGGCACAAGCT ATGCAGACCTCTAGATAAACATTTCTAGGAAGAGGGATCAAAAATGAAAATATTCTGGGG TGTGTGTGTGCCTGTGTGTGTATGTAGTGGGTGATGGGATAAGGCCTCTCCTTCTCCTGG AGGCCACTGTGGCTGGAGCTGAGTGAAAAAGAAGAAAATGGTAGGAGATGCAGTGTAGGT GGTCTTCGGAAAAGAATGGGAAGCCAGATCCTGCGGGCCATCTGGGAGAGGATGGCTTTT GTTCTGTGGGAGATAAGGAACCACTGGAGGGCTTGGAGCAGAGGTGTGACATCGGGCTTC CATTTTTTTTTCAGTACTACTTTCACTGCTTTATTAGGAATAGATTGTAAGGGATGCAGT AGAAGCAAGAAGTCAGGTGGCTGGTTATGGGGTTATTGTCTTCTGAAAGCCACGTAAAGA AAGTGAAAGGTGATGGTGACCAGTGAAAGTGGTGAAAAATGATCAAGATTTACAGACAGT TGAAGGCAGAGCTATAGGACTTGCTGATGGATTCAGTGTGATGTGAGAGAGAGGAGTTAA GGCTCTCTCCAGGTTTTTGGCCTCAGCTAAGTAAGAAATTGGCCTCACCTGACAAGGAAA ACAGTGAATGGAGCATGTTTTGTTGGGAGATGGGCTTGGGGGTGGAGGGTAGGAACTTGG TTTTAGACCTGTTAAATTTAAGATTCTTTAAGACATTGAAGTGGCGAGGCTAAGTTAGGT AATTTAATATAGGACTCTGGAGTTCAGTTGAGTAAAACATATAAAGTCCTGAAACTGGAC AACATACCAAGGAAGTGAATGTAAATTTAAAAGACAGAGAGAGGCCCAGAGACTGAACCT TGGGGAGACTAAATATTTAAAAGTCAGAAGATAAGATGAATGCAAACAGTGAGGTGAGGT AGGAAGAAAACCAGGGGAGTGTGGTGGCCTGGGAGCCAAGTAAAGTGCTTCGAAGAGGAG AGAGTGACCAGCTAAGTCAGTGCTGCCCAGACCTAAAAACATGAGGACTGAGAAACAAAT GCTGGATTTAGCAACAGTAAAGTCACTGTTGGCCCCAACAGAGATGATAATGAATGGTTT ATATTTGGAAGACAGTAAGTTAGCAAGAGTAGGTTTATACTGAGAAATAGTGGAAGATCT GGATAAAGGGAGGCCAGAAAATGGAATGCTTTAGGTGCCAAATTGGAGAGTTTGGCCTTT GCCTTATAGAAAAATTACAAATAAAGGTATTTATATGGGACAAGAATAAAGCCAGTGTTT TTGAAAGTTTGCCTGATAGTAGTGGATGAGGAGAGGAGGGTCTTGATGCAGTAAGACCAG TCAGGAGTTTGTTCTAAAATTGAAGCTTATCAGGAGGGTAAAAACAAAGATGGAGGAAAA TGAATAGATGTAGGATGACTGATAGAACATAGAGAATGAGAGAACAGACACCTAAAATGA TTCCGATGCTGCCTGAGAGAAGGATGGTACCAGCAGCCATCTCTGGGCTTCAGGTTAATA TGAACTAGCTTTAGAGATGGGCTGTCCTTGGAAAGTTTGAGACACAGGAATTGTCCCCAG GTATGCAAAGCTGAAATAAGTTTTAGGGATCAGGAATATTTGTTGGACATATCGGAATCT CATACTAAGTCTGGGATATAAAGGCTGGAGAAAGAGATACACTAAAGCACAGAGGCCATT CTTCGTGGGGAAAGAGATTGCGGGAGCCCTGGGAGATTCTGTGATGGGGCTATGATCTAG ATCCTTCACAGGTCAGGCCCAGCAGAGGGAGCATTCTCACAGGTGATACAATTATTACAA TTATGAAAGATAGGCAAGACAGTTGTAAACAACTCTCCCCTCCTTAGGGAAAAAAAATGG ATCTGCTGGCTTTTAGAGGAAGTCAGTAAGATTTAGGGAATGAGAAAATCAAAACCTGAT GTATTAATCATTTTTCAATTTGTTTTGGTAGTTCTACCCTAGAACATGTAAAAGTTGTAG AACTTTAGAATAAGAAAAGAATGTACAGATAATTGAACTATTTACTACTCTTTTACAGGT AATGAAATTGAGGCTCTAAGAGCTTCAGTGCTATTTAAGAAGTCACTCTTCTAGTTCATT TCAGCTTGACAGATGTTTATTGAACTCCTATTTGCCAAGTACTGTGCAAGGTGCTGAGAA TACAAAGGTGAATAAATGACAAGAGAGGTTATTAGGCTGCAGATCATAGAAGACCTTATA GGCCATCATAAGGATTCAGGTCCTTATGATAAAAGGATTGGGAAGCCTTTGATGTTTGGA TTGTTTGTTTGTTTGTTTTGTTTGTTTGTTTTTTTGAGAGGGAGTCTGGCTTGTTGCCCA GGCTGGAGTGCAGTGGCACAATCTCTGCTCACTGCAACCTCCACCTCCCTGGGTTCAAGT GATTCTTCTGCTTCAGCCTCCTGAGTGGCTAGGTCTACAGGTGCCCACCACGCCCAGCTA ATTTTTGTATTTTTAGTAGAGACGAGGTTTCACCATGCTCGCCAGGCTGGTCTTGAACTC CTGACCTCAGGTGATCCGCCTACCTCGGCCTCCCAAAGTGCTGGGCTTACAGGCTTGAGC CACCGTGCCCGGCCATTGAAGTGTTTTAATGGGGAGGGCTATGAGATGGCATGATCAGGT TTGTGACTCCAAAAGATCATTTGAATCTATTTCTTTTTTTTCTTTTCTTTTCTTTTTTTT TTTTTTTTTTTTTTTGAGACAGAGCCTTGCTTTGTCACCCAGGCTGGAGTGTACTGGTGC AATCTTGGTTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTACCTCAGCCTC TCGAGTAGCTGGGATTACGGGCACGCGCCACCATGCCCAGCTAATTTGCTGATTTTTGGG TATTTTTAGTAAAGATGGGGTTTCTCCATGTTGCCCAGGCTGGTCTTGATCTCCTGACCT CAGGATCAGATCAAGTGATCTGCCTGTCCTGGCCTCCCAAAGTGCTGGGATTACAGCTAT GAGCCACCACGCCCCGCCTTTGACTCTATTTCTGAGAATAATCAGGAGAGGAGCAAAAGA TATGGATTGGAGAGATATTTAGAAGTAAAATTGACAGGACTTGGTTATTGATTGACTTTG GGATCCAAGAAAGGGAGAAGTCAGGATTGACCCCTAGGTTTCTGGAGTGGATTTTACTGA GATAATTATCTTTTTTTTTTGGACCTACATTACATTTCAGATTACTTTCAGATCTCTACC TAGAAACATCAAGAAGGCAATGAAATAGACAAGATTATGAATACACTAGGTGTGAATTAG ACCATATAGAGGGCCCTATATGAAGTGAGAACAAAATGCCTAAGAAAGAGCTCCACAAAT TTTAATGACCAGATAGGGGAGGAGCCTGCAGAGAAGACCAAGAAAGAGCAACCAGAATTA GGAGTAGGCGGCTCTAGGCACACTGCCTAGGAGTCAGCCCTGCTCCCTGGGGAGCCACTC TGGAAATTAATAATAATAATAAGCAGAATTAGGAATAAAACCAGGATATTGTAGTGTTAT AGCAGCCAAGGAAAGAGAGGACAGTCAGATGTTGCAGAGAGGTCATTAAGATGAAGACTG AAAAATGTCTGCTGGATTTAACAAAATAGAAGTTTGCAGAGTGATAGGTAGGGAAAACCA GAGGAAGTGGGTTGAAAAATGAGTAAGAGGAGGCTGGGCATGGTGGCTCACACCTGTAAT CCCAGCACTTTGGGAGGCCAAGGCAGGTGAATCACCTGAGATCAGGAGTTTGAGACCAGC CTGGCCAACATGATGAAACTCCGTCTCTACTAAAAATACAAAAATTAGCTGGCTGTGGTG GTGCGTGCCTGTAATCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATTGCTGAGCCCAGG AGGCGGAGGTTGCAGTGAGCCAAGATTGCACCACTGCACTCCAGCCTGAGTGACAGATCG AGACTCTGTCTCAAAAAAAAAAAAAAAAAGTAGGAAGAGAGGATATAAAGATGATAAGTA TGGACAGCTCTTGAGAAATGTTACTGTGAAGGGGAGGAGAGATAAGTAGAGGGTGTGTGT GTGTGTGTGTGTGTGCATGTGTAGGAGTGATTTGAATGTTTAAAAGGATTCAGTTGAGAA AAAGAAATGGTATGCAGGACTGAGAAAAATTGTAAGAGATGGAATTTAGAAACATTTAGG TACAGTAGACTTAGAGAAGAAAAATAGTTGAAAGGTATGAGAAGAGGATATGCAAATGTA GACAGGTTTTTGTTTTGGGTTTTTTCTTTGTTTGTTTGTTTGTTTGTTTGATTCCTTGTT TTTGAGACAGGGTCTCTCTATGTTGACCAGGCCAGAGTGCAGTGGCGCCATCATGGCTCA CTGCAACCTCGACCTCTTGGGCTCAAGCGATCATCCCATCTCAGCCTCCTGAGTAGCTGG AACTACAGGCTCGAGCCACCACACCCGGCTAATTTTTAAATTTTTTGTAGAGACGAGGTC TCACTGTGTTGCCCAGGCTGGTCTCAAACTTCTGGGCTCAAGCAGTCCTCCTGCCTCAGC CTCCCAAAGTGCTGGGATTACAGGCGTAAGCCGCTGCCCCTGGCCTACATAGGTTTTTAT GTTTGATGGCTGAAGGAAGGAACAAATGGTAGGTGGAAACAAACACATCTGTGAATGAAG AAATTTAAATCAAGACAAATAACAGCACTGGTCCTCAATGAGGACAAAGTCCTTAACATA ACTTATATATAATTTTATATATAAAATATTTATAAGATAAAAGGGTCTAAACTCTTTTAT ATAAATATGAAATAAGATTACATATGTTTGTGTATATATATATATAAATAATACAAAGAC CTGTTGATATAAGGTCCTTAAATAATTTAGAGAAGAGGTACTTCTAAATTTCTAGATAAT ACCAAAATGTTTTAGTACTACTCTGGAGATCAAGGTGAACTCTCCAGGTTGATTGGTGAA GAGGCCAAGTGTATTTCATTTTAGACATTTTAGACATGTTTGAGAAAAAGACATTTGGAG AAAAAATTTCACACCATATTTATAAGATGAAAGAGTCTAACTATTAGCAATGTCTCAGTA AAGGGACCTGAGAGTTGTATATTCTTTGCCAGGAATGTCCAACACTTTGGACACTTTGGC AAAGAGACCAACTAAGTACATCCTCAGGAAGAAGCTGAGGCAGAAAATATCAAACAGCTT CTGACTGGTTTAAAATATATACGTATATTTAAATCCCAAGGTGTCTTCACACATTAAACA GTCATCCCTCAGTAACCATGGGGGATTGGTTCTAGGATCTCCCAAGGATACCACAATTCA AAGATGCTCAAGTCCCTGATATAAAATGCTATAGTATTTGCATATAACCTATGCACATCC TCTGTATGCTTTAAATCATCTCTAGATTACTTATAATACCTAACATAATGTAAATGCTAC ATAAGTAGTTGTTATATTTTATTGCTTAGGGAATAATGACAAGAAAAAAAGTTGGTACGT GTTCAGTACAGATGGAGGTTGAATCTACAGATGCAGAGCCCATGGATATGGAAGGCCAGC TGTACTATGTTGAAATATGACTCCTCAAGAGAAACAGCGGAGCAGGAACATGTTCAAAGA AAGGACAACTAAGGCTGGGCTCAGTGGCTCATGCCTGTTATCCCAGCACTTTGGGAGGCC AAGGCAGGAGGATAGCTTGGGCTCAGAAGTTTGAGATGAGACCAGCCTGGACAACATAGT GAGACCCTGCTTCTAACAAATATTAGCCAGTCATGATGGTGCACACCTGTGGTCCCAGCG ATTCAGAAGGCTGAGGTGGGAGAATCACTTGAGCCCAGGAGATAAGGCTGCAGTGAGCCA TGGTTGCACCATGGCTCACTGCAGCCTGGGTGACAGAGTAACCCTGTCTCAAAGACCAAA AAAAAAAAAAAGGAAAAATTATTTATTTCCCTGGAAGTAAGTTTGGGAGATGAACTCAGT TTGTGAATGACCACAGCATATGGGATTGGAACTTCAGCAGGAAGGGTGGTGTCATTGTAA GGAGCCTGGCCTGTGTTCCCCAGTCAAACCAAGTTAACGCCCTTGGATATTCGGCCTTGG TTCTTGGTCCTGGTCCAGCGGCCTCAGGCCTGAACAATGCCAGAGTCTTTCTCAAAGAGA GCATCCAGGAAAAAAAGACACAGTAGCCTCCCTAGGCCTGACTCAGGCTAGTTCTGCCGC CTAGCCTGGTCAGTCTGGCAATCTTAACAATCCTAACGATGCTCCCCTTAGCCCTCCACT GAGGTTTAGCACTAACATCTGGACTCAGGAGTCCTTACTTGCCATCTGCCCTAGCTAATT TCTGAGGGTGCTGGCATGGGGGCACCGTCCTGAGTCCACGGCCTTCACTTCTGCTCACCC ACCTGGTCATGTGCTGAAGAGGCCAAGCAGCTATGAAAGCTTGGGTCTCAGCCAGGTGCG GTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCAAGACGGGTGGATCACAAGGTCA GGAGTTCGAGACCAGCCTAGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAA AAAGAAAAAAGAAAGCTCGGGTCTCAGGAGTGTCTGCTGTTATAATATCCTGCCACCAGG AAGCCTTCGGACTGCTAGAAGAGAAATCTTGCCCCTGGTCCTAGTTGCACCAGCTTTTCC ACTTGGTTCTACACTAACCCTGACTACTGTTGTCTTATCCTCACAGAAAGTTGAGGAAGC GAGCGGCCAAGGTCTCAGCCCGACACCCCAAGCCCCTTGGAAGGTATGGGGCAAGAGCCC CGGGACCTCCTGCTCGCCCTGCGGCCCCAGGAGGTGGATGGATGGATGGCAGCCATCCAT GTCCATCCCAGAACCCAAGCTGATGGATTAGGGATGTGAGGAAAATGGCTTTTCCTGCAG GGAGGTGAAGGGAGCAGGCATGGGGATGGGCAAGCTTTGATCTTAGGGAACACAAGGAGG AAGTAATGTAGGAGTGGCTGAGAAGCCTCCCATCTTTACACCTACCCCAAATAGCTTGGA TTCCAGCCTCAGCCACCTTCATTCTTCCTCCTTCCTGCCCCCTCCATCACCTCCCTTAGT TCACCCACATTCCCATTCTCTCCCCTCTCCACCTTTCCTCTTCCCTTCTCCCCTTCCCAA CTCCCCCACCTGGATTGACATCGCTAGATTTCCCATTACTGTTGCTGAATCCAGAGAGCA GCATGAGTTCCTGAAATGCAGTTCAATGGTGTTCAGCAGACGGTGGATGCGGAAAATCTT CATTTTTCCCATCCCCATGCTGCCCACAAAGGGTCTTTCCCAGAAACAGAAAAATAACCC TGTACCTTTCCTGCGCCACATATGTAACCACTACCTCTACCAACTTCCTTCTCCTTTTTG CGGACCAATCACCAAGCTTAAAGTCAAACCCAAACCCCGAGTGGTCAGGGGGCCACACAA GAGGTAAATAAAATTCAGGTTGGGTGGAAAGGAGAGGGAGCATGGAGTTACTCGGCTGTG GCCAGGGAGGGAGGGGGTCCAGGAGGCCTTTGTGGCTGAAAGAGCTGACCAAGAGGAGGA GCAGCAGCAGCTCTTAGAAATCACCTTCCAGGGCATTTACTGAAGTGTTACGCAAGACTG GTCCTTACCTTGGTCTCAGGAATGATGCTTGTCCTAGGATTTGTTTTTTCACTCACTGAC TACCTCGTTCCACATGTTTACTTATCTTCCCCTGCTGAGTTCCAGGAGACAACATGGTGC TTTTCTCTTTCAGACGCCATACTTGCGTCTCCTGTAAGAGGTTACATTTGCCTAAAGGAT CAGTGTTCCCAAATCAAATGCTTTATTTGATTAGTTGTTAAAAATAAGTGCTACCAGCTT ACTCGAGATGGAGGGAAACTCAGCGTCCCCTTTGGAACCTTTACCAGGAATGCAGTCAGA TTGACAGCCCCTGCCTCTCTGGCTCATTTTCCACAATTAGGCTCCCAGTTCCCTAATTTT CCTCCTGGGCTCCTTTAGAACTCGAAGTGGGAAGCTTCCAACCCCTGTAATTACATCTAA CTTGTCTTCAAAAGGCAGTTTGCACATTAAAAGTCTCCCTGATAACTTCAAGAGGGACTG AAGTATCGATAATTCATCCCTTTCTCCCCTCCTGTTCTCAACAAGTTCTAGTCTCACCCA GTGGTCCCCTCATAGCCCTCATTCCCCAGCTTCTCTGGTGGTTTCAAAGGATCTCAGAAA TTTGGGGATGTTCTTGTAGTGCCCTTCTAGCTTAGGGTCATCTTTGCCCAACATGGCCAC ACTCTAGCCTTCCCTGACCTGCACATTAAAGTACACACTGCCATTTTTATTTTGTTCATT GTAGACAACGGGAATGAGGATGTTTAGAAGATAGATGTATTTTTCCTGTGATGGGCTCCT TGACTTTTACTTTCAGCCAAACAGGACTGTGGGAGAGTGCCTGATCTCTTAGATCTTCAG GATCCATTTATCCTGAGCTTCCAAAGGTATTCTGTAAAGTCTCCAGGCTTCCTTTGTCTG TTTTGTGTATAAACTTTTCCTCCTCCTGTGTCTTCCTAGCCAATGGCTTCAAGTCATCAT ATTCCATCCTTCCTCTGACATCAAGTGATAGGGCACATTATTGCAATAATGCATGACTAC ATCAGCCTCACAGGCCCGTTCCACCAGCACCAGACCTCATTTTCTTCCCTTTCTCTGCGG GCAGAGTGTACTTCACTCTGGCACGTGCCTCACTGCAGCCTCTCATTCTACTGGTATCGA TAAAGAAGTCCCCCCATTCTCTCAAACATCTCGGCAGCATTTCCAAGCCTTAGCATCTAT AGTTCAGTCCCATTATCCTATTCAGATGGCTTTGGGACACTGTTACGTTGAAATTGCAGA AGCATGGACTGCCTTTTTAAAGACTTACACAGCACAGGTCCTGGGATGTCTTTGCCATTT TGTTGTTCACATCCATCTCCTTTCTCTGGTCATTTATTCCCTCAAACTTTGACCTGTCCT GCATTTATACATCTTCATTCTTGCATATGCCAGTCCCAGTTTTTCTTGCGTCTACCTGCT GGTCTGTTCTTGCTGCATCTGCCCCTCCTAATCTGTCCTGCAGAGTCTCTGGCCTCTGCG GAGCTATGGAGATGGGAGACTTCCTTAGTCCTTTGCATCCTGACTCATTCAGTTATTCCA GTCTCAGCATCACAGAAGGACTTGCTCGCCCTGGCTTTTCAGGCTTCCTGTGTCAGCCAC TCCCTCCTGGCCATTTCTTCCAACTGGAAAGTCCTGGTTTCCCCTTCCCTGAGGCCTTAG CCTCAGCCTCCTTTAGGGCCAGCAGCCTGAAACCACTTGGAACAGTTTCTTCCAGGCAAG TCGAGACTAGCCATCCTTCTCTTAAGGTTGTTCTACTGCAGGAGGTCCCCAAGGCCCCTC CTATCTGGGTAGTTGAGGCTCCCTCAGCCTGGAAACTCAGCAATCCCCATGTATCTCCCG AGGGAAACATGGAAGGGGGAAGAAGAGGAGATAAATGGTCACAAAAGGGTGGGGGGCATG GTGGAGGCATGAAGTGGGAGGATGTTTGTGGGGCCAAGAGGCAGGAGCATTGTTTTACCC TACTGCACCTCACTCCTGTCCCCCTAGGCTGCTAGCCCAACGGCAGCAACACTCCTTTGG TCTGCATGGGGTGGCGTGCGTGGGCACGGAGGCCCACCTCTCCCTCTGTTCCCTGGAGTT CTATCGTGCCAATGACACCGCCAGGTGCCCTGGGGGGGGCCCTGCAGTGGTGAGCTGTGT GCCAGGCCCTGTCTACGCGGCATCCAGTGGCCAGAAGAAGCAACAACAGTCGAAGCCTCA GGGGGAGGTGTGTGAGACAGTGATTATGACCTTTCCCACCCCAGGTGGAGAACCCCTAGC CTGGCAACCCCAGACTAAGCACAGCCCTGACCTTTGAGGACAGAGAGGAGCCTTCCAGGG GGTGGGCCACAGACCTGATACCACCCACTCCCTTCCACCAAAGTCTCACTCATCTCCCAG GTCTGCTTAGCCCTCCGTGCAGATGTTGCCATTTGCCTCTGTTGGGCACTTCTCTCTTCT ATAGGCCCGTGTCCGTCTAAAGGGCGGCGCCCACCCTGGAGAGGGCCGGGTAGAAGTCCT GAAGGCCAGCACATGGGGCACAGTCTGTGACCGCAAGTGGGACCTGCATGCAGCCAGCGT GGTGTGTCGGGAGCTGGGCTTCGGGAGTGCTCGAGAAGCTCTGAGTGGCGCTCGCATGGG GCAGGGTGAGGTGGCATGGAGGTGGGAGGGAGAGGGAAGGAGGTACATGCTCCTGGGGGG CATATTCCTTCGGAAGGTTAGGTGTCCCCTGGGCAGACAATATATGCTTAATTACAACTT CCTGATCTTTGCCATCTGGCCCTAGGCATGGGTGCTATCCACCTGAGTGAAGTTCGCTGC TCTGGACAGGAGCTCTCCCTCTGGAAGTGCCCCCACAAGAACATCACAGCTGAGGATTGT TCACATAGCCAGGATGCCGGGGTCCGGTGCAACCTACCTTACACTGGGGCAGAGACCAGG GTCAGTCATCCTCTCTACCTTGGTTGAGGTCTCTTTCATCCTATCCAGGTCTGGTCTCCA ATCTACAGTCCAATGGCCCCCAGCCCATTGCCCCAGGCCCCTGCCCTCCTGCAGCTCCCA CCTGACCCATCACTTGCTAGCCCATTATGTGCCTGAGTCACGCTTCAGCCACATCTGTTA GAGACTCCCACTACCTCACCCCAAAGCTTTCTCCAGCGCTTCCATTCTGTGTCACTACAG ATCCGACTCAGTGGGGGCCGCAGCCAACATGAGGGGCGAGTCGAGGTGCAAATAGGGGGA CCTGGGCCCCTTCGCTGGGGCCTCATCTGTGGGGATGACTGGGGGACCCTGGAGGCCATG GTGGCCTGTAGGCAACTGGGTCTGGGCTACGCCAACCACGGCCTGCAGGTGAGTGGGAAG GAAAGGGGAGCCGAGGCTGTTGTCTCAAAGCCTGTGTTTTGGGCAGAGGGCTGAGGAATG AGTCCCTTGGCCCAAGATGCTGGATCCTGGGCCTTACAGAAACATCTGCATATGTCCCCA GGAGACCTGGTACTGGGACTCTGGGAATATAACAGAGGTGGTGATGAGTGGAGTGCGCTG CACAGGGACTGAGCTGTCCCTGGATCAGTGTGCCCATCATGGCACCCACATCACCTGCAA GAGGACAGGGACCCGCTTCACTGCTGGAGTCATCTGTTCTGAGAGTGAGTGAAGGAGGGG GTGATGCATGCCAGGGAAGGGAGTGTCTGGGCCACCCGTTTGCAGGGAAAGGGGGCTGTA ATCTGGAGGGGCACTTCTTCCCCATAAAAGAGCCAGTTTCGCCGGGTGCAGTGGCTCACG CCTGTAATCCCAGCACTTTAGGAGGCCAAGGCGGATGGATCACGAGGTCAGGAATTCAAG ACCAGCCTGACCAAGATGGTGAAACCCTGTCTCTACTAAAACTACAAAAATTAGCCAGGC GCAGTGGCAGGCGCCTATAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGA ACCCAGGTGGCAGAGGTTGCAGTGAGCCAAGATCACGCCGCTGCATTCCAGCCTCGGCAA CAGAGTGAGACTCCATCTCAAACAAACAAACAAACAAAAACAAAAACAAAAAACTAGTCT TACACACTAGGGAGGGATGGAAGCACCCCTCTCTGTGAAGTCAGCAGTGACTTCTAACAC CCCCTTCCTTTCTTGGTGCAGCTGCATCAGATCTGTTGCTGCACTCAGCACTGGTGCAGG AGACCGCCTACATCGAAGACCGGCCCCTGCATATGTTGTACTGTGCTGCGGAAGAGAACT GCCTGGCCAGCTCAGCCCGCTCAGCCAACTGGCCCTATGGTCACCGGCGTCTGCTCCGAT TCTCCTCCCAGATCCACAACCTGGGACGAGCTGACTTCAGGCCCAAGGCTGGGCGCCACT CCTGGGTGTGGCACGAGTGCCATGGGTGAGAGGGTAGGGAGTCAAGTAGAAGGGCAAGAC CACGGGGGATGGGGCAAACCTTCTGGGGGCAGAGAAGGAAACAGAAGTTCCCTTCTCCCC ACAGGCATTACCACAGCATGGACATCTTCACTCACTATGATATCCTCACCCCAAATGGCA CCAAGGTGGCTGAGGGCCACAAAGCTAGTTTCTGTCTCGAAGACACTGAGTGTCAGGAGG GTGAGTTGGGGACTGAAGTGAACCACATGGTATCCATTGCACAGCCTTTCCTTACACTGA CATATGCCAATCCCTCCAGATGTCTCCAAGCGGTATGAGTGTGCCAACTTTGGAGAGCAA GGCATCACTGTGGGTTGCTGGGATCTCTACCGGCATGACATTGACTGTCAGTGGATTGAC ATCACGGATGTGAAGCCAGGAAACTACATTCTCCAGGTACCTGGAGTCTGGGGCTTCCAG ATGGGTGAGTGGGGGGAGCGTTAAAGACACCTTTGAATTCGAGGATTGTCGCTGGGTTAA GTGGCCTTTTTCTCACTCACAGGTTGTCATCAACCCAAACTTTGAAGTAGCAGAGAGTGA CTTTACCAACAATGCAATGAAATGTAACTGCAAATATGATGGACATAGAATCTGGGTGCA CAACTGCCACATTGGTATTTGATGGGAAGAGCAACCCAGGAAGATTAGGGGATGGGAGGG AAAGACGTTCATTCTCTTTTCCATAGCTTGTTTCTCCATCTTCCCACCTTCCTGTAGAGC TCTCAGTCCCTCCACTTCTACCCACCCTTCTCCACAGTGCATCTATCTCCCTCCCTCTGT GCAGGGCGCCTCCCAAATTGCCTGTCCACTCTGCAGGTGATGCCTTCAGTGAAGAGGCCA ACAGGAGGTTTGAACGCTACCCTGGCCAGACCAGCAACCAGATTATCTAAGTGCCACTGC CCTCTGCAAACCACCACTGGCCCCTAATGGCAGGGGTCTGAGGCTGCCATTACCTCAGGA GCTTACCAAGAAACCCATGTCAGCAACCGCACTCATCAGACCATGCACTATGGATGTGGA ACTGTCAAGCAGAAGTTTTCACCCTCCTTCAGAGGCCAGCTGTCAGTATCTGTAGCCAAG CATGGGAATCTTTGCTCCCAGGCCCAGCACCGAGCAGAACAGACCAGAGCCCACCACACC ACAAAGAGCAGCACCTGACTAACTGCCCACAAAAGATGGCAGCAGCTCATTTTCTTTAAT AGGAGGTCAGGATGGTCAGCTCCAGTATCTCCCCTAAGTTTAGGGGGATACAGCTTTACC TCTAGCCTTTTGGTGGGGGAAAAGATCCAGCCCTCCCACCTCATTTTTTACTATAATATG TTGCTAGGTATAATTTTATTTTATATAAAAAGTGTTTCTGTGATTCTTCAGAGCCCAGGA GTCAGTGCTGGTGGTTGGAGGGACCTGCCCCCACTGGTTCATTTAACCCTCTGTCTCGGT GCCCTCAGAACCTCAGCCAGAAAGGCAAGGAGGAAATCAGAGCAGGAGCCTCATACTCTT GGTGATCTATTCATTCTGTGACCTCAGGGGTCACATATAAGGTCAGTGTTTCTCGTCCCC GCCGGATCTGCACTGCCAACTGGGATTGGGTTCGAACAGCTTCATAAACATCTTCAGCAT TTTGTACCATCTGCTCCCCAATGGCCAAAATCACATCACCAGGCCGCAGACCAGCCC OMIM ID 607163