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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LNX1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84708
Official gene symbolLNX1
Full nameligand of numb-protein X 1
Aliases,LNX,MPDZ,PDZRN2,
Gene summaryThis gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q12
Gene position54457724 - 54326437  Map Viewer
Gene orientationminus
Gene size131288 bp
Gene sequence
OMIM ID609732