Entrez gene ID | | 84708 |
Official gene symbol | | LNX1 |
Full name | | ligand of numb-protein X 1 |
Aliases | | ,LNX,MPDZ,PDZRN2, |
Gene summary | | This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q12 |
Gene position | | 54457724 - 54326437 Map Viewer |
Gene orientation | | minus |
Gene size | | 131288 bp |
Gene sequence |
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OMIM ID | | 609732 |
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