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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HAVCR2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84868
Official gene symbolHAVCR2
Full namehepatitis A virus cellular receptor 2
Aliases,FLJ14428,KIM-3,TIM3,TIMD3,Tim-3,
Gene summaryCD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]
LocationChromosome: 5   Locus: 5q33.3
Gene position156536138 - 156512843  Map Viewer
Gene orientationminus
Gene size23296 bp
Gene sequence
OMIM ID606652