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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO18 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID84893
Official gene symbolFBXO18
Full nameF-box protein, helicase, 18
Aliases,FBH1,FLJ14590,Fbx18,MGC131916,MGC141935,MGC141937,
Gene summaryThis gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10p15.1
Gene position5932214 - 5979556  Map Viewer
Gene orientationplus
Gene size47343 bp
Gene sequence
OMIM ID607222