Entrez gene ID | | 8490 |
Official gene symbol | | RGS5 |
Full name | | regulator of G-protein signaling 5 |
Aliases | | ,MST092,MST106,MST129,MSTP032,MSTP092,MSTP106,MSTP129, |
Gene summary | | This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Location | | Chromosome: 1 Locus: 1q23.1 |
Gene position | | 163172963 - 163112089 Map Viewer |
Gene orientation | | minus |
Gene size | | 60875 bp |
Gene sequence |
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OMIM ID | | 603276 |