Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPFIA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8499
Official gene symbolPPFIA2
Full nameprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Aliases,FLJ41378,MGC132572,
Gene summaryThe protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein is most closely related to PPFIA1, a liprin family member known to interact with the protein phosphatase LAR. The expression of this gene is found to be downregulated by androgens in a prostate cancer cell line. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q21.31
Gene position82153109 - 81653356  Map Viewer
Gene orientationminus
Gene size499754 bp
Gene sequence
OMIM ID603143