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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPFIA1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8500
Official gene symbolPPFIA1
Full nameprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Aliases,FLJ41337,FLJ42630,FLJ43474,LIP.1,LIP1,LIPRIN,MGC26800,
Gene summaryThe protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.3
Gene position70116823 - 70230502  Map Viewer
Gene orientationplus
Gene size113680 bp
Gene sequence
OMIM ID611054