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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ABCC11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID85320
Official gene symbolABCC11
Full nameATP-binding cassette, sub-family C (CFTR/MRP), member 11
Aliases,EWWD,MRP8,WW,
Gene summaryThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q12.1
Gene position48269088 - 48200822  Map Viewer
Gene orientationminus
Gene size68267 bp
Gene sequence
OMIM ID607040