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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID85363
Official gene symbolTRIM5
Full nametripartite motif-containing 5
Aliases,RNF88,TRIM5alpha,
Gene summaryThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15
Gene position5706339 - 5684425  Map Viewer
Gene orientationminus
Gene size21915 bp
Gene sequence
OMIM ID608487