Entrez gene ID | | 8540 |
Official gene symbol | | AGPS |
Full name | | alkylglycerone phosphate synthase |
Aliases | | ,ADAP-S,ADAS,ADHAPS,ADPS,ALDHPSY,DKFZp762O2215,FLJ99755, |
Gene summary | | This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q31.2 |
Gene position | | 178257471 - 178408564 Map Viewer |
Gene orientation | | plus |
Gene size | | 151094 bp |
Gene sequence |
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OMIM ID | | 603051 |