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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAPKAPK5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8550
Official gene symbolMAPKAPK5
Full namemitogen-activated protein kinase-activated protein kinase 5
Aliases,PRAK,
Gene summaryThe protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.12-q24.13
Gene position112280279 - 112331228  Map Viewer
Gene orientationplus
Gene size50950 bp
Gene sequence
OMIM ID606723