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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for USO1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8615
Official gene symbolUSO1
Full nameUSO1 vesicle docking protein homolog (yeast)
Aliases,P115,TAP,VDP,
Gene summaryThe protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21.1
Gene position76649829 - 76735366  Map Viewer
Gene orientationplus
Gene size85538 bp
Gene sequence
OMIM ID603344