Entrez gene ID | | 8615 |
Official gene symbol | | USO1 |
Full name | | USO1 vesicle docking protein homolog (yeast) |
Aliases | | ,P115,TAP,VDP, |
Gene summary | | The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q21.1 |
Gene position | | 76649829 - 76735366 Map Viewer |
Gene orientation | | plus |
Gene size | | 85538 bp |
Gene sequence |
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OMIM ID | | 603344 |
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