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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RFXANK (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8625 Official gene symbol RFXANK Full name regulatory factor X-associated ankyrin-containing protein Aliases ,ANKRA1,BLS,F14150_1,MGC138628,RFX-B, Gene summary Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq] Location Chromosome: 19   Locus: 19p12 Gene position 19303008 - 19312678  Map Viewer Gene orientation plus Gene size 9671 bp Gene sequence >RFXANK:10565810..10575480:Length=9671 CCGGACGCCGCACGGCTCCTGTTCCGGTGTCAGAGGGCCCGCCCTCCCCGCTCCTCAGTC TTTGCGGACAAGAAAGGGGCTGTGTGAGACGCAGGGAAGGAGGCACACCCGGGGGTGGCG CAGTGAGGAGGGGGCGCGACGGCCAGGAGGCTGGTGGAGCGACACCCAGGCAGGAGAGGG GGAAGAACTCTCTCCCTTTCTGAACCCCCTTTTCCTTGAGAGACGAGTTGGGGGAGTCCT CCACGCATTACCCACTCGGGCCGCAAAAACTCCCTTCTTTAGCCCTCTGCCCCCGCCCTT GCTTATAAGCCTTTGAGACCGCAGAAGGGACCTTGTTGTGGAACGGGACGGCCAAGGTAC GCTGCCCCTTTAAGTTCCAGACGCCCCGCGTACTTCCCCTACTTCTTCTTCTTGAGATAG CCCCGCCCATCTACCCGAAGCCGGAGCCAATTGGCTCCCTCTGGAAAAATCTGTGGGCAG GGTAAAGGTGAGCGGGCGCAGGCGTAGTGAAATTCTCAGAGCCCTTTAGGCCCCGCCCAT TCCCTCCGAGTCGGTGAGGAGGGGAAAAGAAGGCGCAGGCGCAACTGCCCTCCCAGGACC CCAGCGGAACCCACGCCCTCCCCTAAGTCTTAAAGGGCCAGAGGCAGCACTTACTGCCCG GGCCCTTCCTCACTTTTGGGGGGCGGGGGTGCGCAAGCGCAGTGGGGGAGCTCTGGGGTG GGGGTAGCGGTCGAGTATCAAGTTGCTTTCTGTCCCGGCAGAGGAAGCCAGATCGCTGAG GGTCCGGTCTCCAGTTTGCCTCCTGCTATATCCATTGGAAGAGAAAAGTTTGTGACTTGG GCCCCCAAGTTTTGAGAGAACTGGGCTTTCGGCGCGGGGGGACAGAGGAGGCTCGTGGGG AGGTGAGTGGACCTCCTGGATCGATTTAGGAGGCTCGGGTGGGACTGGGACCAATCGCAC CTTTGTTGAGCCGTCACTCATTATGGGGAGCCCCTCCCAACAACCATAGCGAATATTTAT TGAGCTCCACGCTTAGCAGATCCCCCGATAAGCTATGTACAGACATAATTCGTTGTAGGT CTCATTTCCACATTTTGTCGTGGAGGAAACTGAGGCTCAAAGGTTAAGTCACGTGCCCAA GTTCTCACGGCCTATAAATTGAGGGATTCGAACCCAGACAGCTGACCCCAGAGCCCCGGC TTTTTTTTCCTTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCG CCCCAGCTACAGTGCAGTGGTGCGATCTCTGCTCACCGCAACCTCCACCTCCCGAGTTCA AGCAATTCTGCCTCAGCCTCCCGAGTAGCTGGGATCACAGGCGCCCGCCACCGCGCTTGG CTAATTTTTGTATTTTTAGTACAGATGGGGTTTCACCATGGTGGCCAGCCTGGTCTCGAA CTCCTGACCTCATGATCCACCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGCCGTGAG CCACTGTGCCCTGCCAGAGCCCAGGCTCTTAAACATTGCACATTGTAGGTGCTTTGGTGG TGGGGAATGGTAGACCTCGAAAGCAGTTGGACTCTGGTTTTCATTTCCCTGGCTCTGGTA ATTAACCTGGACCTCAGTTTACCCACCCTCACAGTGCAAGGCTAGGTATGCAGTCGGTGC CTACTTTATTATAACTGTTGATAATTATTGTCATCTCTCCCCTTCTGACACCTCCGCCAG CTTTCCCCATGGAGCTTACCCAGCCTGCAGAAGACCTCATCCAGACCCAGCAGACCCCTG CCTCAGAACTTGGGGACCCTGAAGACCCCGGAGAGGAGGCTGCAGATGGCTCAGACACTG TGGTCCTCAGTCTCTTTCCCTGCACCCCTGAGCCTGTGAATCCTGAACCGGATGCCAGTG TTTCCTCTCCACAGGGTAGGATACCTCCTCTGGGATTAGCCCTCTGGGATTCCATGATGA TGGAATGTCAGGCCTCACATGGAACCTGTGTCTTGCTTTCGTTTTTGTTTTGTTTTGTTT TGTTGTTTTTTGAGATGGAGTTTTGCTCTTGTTGCCCATGCTGGAGTGCAATGGCGTGAT CTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAACTGATTCTCCTGTCTCAGCCTCCTG AGTAGCTGGGATTACAGGCTTCCGCCACTACGCCCAGCTAATTTTTTGGGTATTTTTAGT AGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCC GCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCGGCCTGT TTTTGTTTTTTGATACAGGGTCTCGCTCTGTTACTAAGGCTGGAGTGCAGTGATGCAATC ATAGTTCACTGCAGCCTCAACTTCCTGGGCTGAAGCCATCACTCAGCCTCCCTAGGAGCT GGGACTATAGGCATGCAACCACACCTGGCTAATTTTTTTTTTTTTTTTGGGAGGCTGGTC TCCACCTCCTGGGCTCAAGTGATCTGCAGGCCTCCACTTCCGAAAGTGCTGGGATTACAG GTGTGAGCCACAGTGCCCGGCCCTTCACACCTGTTTTTAACTCTTTGAGGGTAGATAGCT AGGAGTGAAATTACTGGGTCAGATGGTCATCCTGTTTTACTTACTGAGGAACTGAGGATT TATTTTTGATTGGAGTCCAAGAATATGCCTAATTTAGTTCCCTCCCACGACCTTTGTTGC TGCCACTCCTGTCTGGAATGCTCTTCCTACACTTCTTCCTATAGCTGACTCCCCTCCCCT CCCTCCCTTCCCGCCTCCGTTTTTTTTTTCTTTCTTTCTTTCTTTTTTTGAGATGGAGTC TCGCTCTGTCGCCCAGGCTGGAGTGCATGGAGTGCAGTGGCGCAATCTTGGCTCACTGCA AGCTCCACCTCCCGTGTTCACGCCATTCTCCTGCTTCAGCCTCCCGAGTAGCTGGGACTA CAGTCCGTTTTTTTTTTTTTTTTTAAATGGAGGTTTGCTTTTGTTGCCCAGGCTCCCTCC CCTCCCCTCGCCTCCCCTCCCCTCCTTTCCCCTCTCCCCACTCTCGAGACGCCTCCTGGA TCCCCTCTCTTCTTGAGACAGAATCTTGCTCTGTTGTCCAGGGTGGAGTGCAGTGGCACT ATCTTGACTCACTGCAACTCCCTCTCCTGGGTTAAGGTGATTCTCCTGCCTCAGCCTCCC AAGTAGCTGGCATGCACCACCACATCCAGCTAATTTTTGTGTTTTTAGTAGAGATGGAGT TTTGCCATGTTGCCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATTGCCCGCCTCGGC CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGTCCCTGTAGCGGATTTC TTTGACTTCCTAAGATCTCGGTGGTGTCACCTTGGGGAGGCCCTCCTGTTACCACCTTGT CTAAGAAGGACTTATTCCTTGTGCTCCGTTCTTTTCATCCTCTTCTACCTGCTTTTAAAT TTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTTGTTGCCCAGGCTGGAGTGC AGTGGCGTGATCTCTCTCACTGCAACCTCCACCTCCTGGATTCAAGCGATTCTCCTGCCT CAGCCTCCCGAGTAGCTGGGATTACAGGCATCTGCCACCATGCATGGCTAATTTTGTGTT TTTAGTAGAGGTGGAATTTCACCATGTTAGTCAGGCTGGTCTCAAACTCCTGACCTCAGG TGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCG GCCTTAAGTTCTTTTGAACACTTATTTCAACTTGAAGTTTTTTATTATTTCTCTATGTCT GATGCACCTACTTGACCCCCGACTCCCTAGAGGGCAAAAACTATGTCTTGTTTGCTCAGA ACATTGCCAGGCAGGGAGGAGAAAGATGCACCCTGGGTATTCAAGAGAGTAGAGTGAGTG AATGGTGGAGTCCCAGGCACTGCCTTTGGTAGCTCCAAGACCCCAGGGAGATACCGAAGG CAGTAGCATGGTAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCACGGCAGGAGAAT TGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCGACAGAGCAAGACTCCATCTCTACCA ATATATATATATTTTTAATTTGCTGGGTATGGTGGCACCTGTAGTTTCAGCTGCTCAGGA GGCTGAGGTGGGAGGTTGGCTTGAGCCCAGGAGGTTGAGGCTGAAGTGAACTGTGATCAC ACCACCGCACTCCAGCCTGGACAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAACCC CAATAGCTGGGTGTGGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCAGG TGGATGATTTGAGGTCAGGAGTTTGAAATTAGCCTGGCCAACATAGCGAAACCCCGTCTC TACTTAAAATACAAAAATTAGCCAGGTGTGGTGGTGGGCGCCTATGATCCCAGCTACTCG GGAGGCTGAGGCACAAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGAT CACGCCACTGTACTCCAGCCTGGGGGACAGACGGAGACTCCATCTCAAACAACAACAGCA ACAAAAAAAAACAGATGGGCTTCTGTCCTGAAGCCTCAGAGACATCTACTGAGGGGAAAC TGACGCCTGTTGTCTGTTTCCCAGCAGGCAGCTCCCTGAAGCACTCCACCACTCTCACCA ACCGGCAGCGAGGGAACGAGGTGTCAGCTCTGCCGGCCACCCTAGACTGTGAGTGGGCCC ACGGTCCCCAACAAGGAGAGGAGTAGGAGGGTGGGAGGGCCTGTGAGGAGCAATCGTGGA CAGAGGGTAAACTGAGGCACAGAGAAGCAAGGGGATGAGTGAGGACTCTGCCTCTGTCCT GCCCCAGCCCTGTCCATCCACCAGCTCGCAGCACAGGGGGAGCTGGACCAGCTGAAGGAG CATTTGCGGAAAGGTGCGTGTCCACACACATGTGCTGGCATGTCTGCACCTGGCTGGTGT GTGCATATGGGTGTCCATACCCACTCATGACGTGACCTGTGAGTGTCCACGTGTATGATT GTATCTAACTGTGTGTGTGACCGTGTTCATGTATGTCCATCAACATACGCTCCCCCTCAT TCCCCTGTCTAACCCCAGCCCCCCACCTCGTCCCCATTTGGCAGCACTGGGGATAGGGGG CAGGGGTGCAGCCTGGTGGTATTGCCCGCCTCCTCCTGCCAGGTGACAACCTCGTCAACA AGCCAGACGAGCGCGGCTTCACCCCCCTCATCTGGGCCTCCGCCTTTGGAGAGATTGAGA CCGTTCGCTTCCTGCTGGAGTGGGTGCGTCCCAGCCCAGCTGGGCAGCTGGGGGGTTCCC GGGGGCCTTAGGGTGGGCTGGGGTTTTGGCTGTGTCTGCTGGCGCCTTGTCTTTGAGATG CGGCTGCTGGCTGGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGG CGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCCGGCCAACATGGGTGAAACCCT GTCTCTACTAAAAAAATACAAAAATTAGCCAGGCGTCGTGGTGGGTGCCTGTAATCCCAG GTACTCTGGAGGCTGAGGTGGGAGAACTGTGTGAACCTGGGAGGCGGAGGTAGCAGTGAG CCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTATCTCCAAAAAA AAAAAAAAAGATGCGGCTGCTGTGGGTACCCCAGGATTCCTGGTTATGCCCCAATCCATC CTACCACTGTCCCTTCTTCTCCCTGCAGGGTGCCGACCCCCACATCCTGGCAAAAGAGCG AGAGAGCGCCCTGTCGCTGGCCAGCACAGGCGGCTACACAGACATTGTGGGGCTGCTGCT GGAGCGTGACGTGGACATCAACATCTATGATTGGGTGAGGGACTGCCCATCCCCAGGACC TCTCAGCCTCCTGGCCTTCATTCCTGCCTCAAATGTTCACAGAGTACTTGAAAGGTGCAG GCCTGCTCTAGGTGCCGAGAACACGAGACAGCCCCATTCCCAGCCTCACAGAGCAGAGCT CCCCATGCAGGGAAGGCAGACATGGAAACAGGCAGCTGAGATGCAGTGAACTGCGCTGCG ATGGCAGATGCACAGGTGGCTACAAGAGCCCCATGTGGGCAAGGGAAATCAGAGAGGTCT TCCTGGAGGAAGGTGTCTAAGCTTGAGACCCCAGAAAGTGAGATGGGCCCAGTGATGAGC AGGAGGAACCACGTTCAACTGGAGGCCAGAGAGTACAAGGCATTTTGAGAATGAGGAAGA GGTAAACCTTTGGTTTCTCCTGCCCCTACCCACGACAGAATGGAGGGACGCCACTGCTGT ACGCTGTGCGCGGGAACCACGTGAAATGCGTTGAGGCCTTGCTGGGTGAGTGGGAGTCGG GAGTGGCCCTGGGGGCCCCAGCACTCCAGCGGGCCCTGCGGGAATCCTGAGGGCAGGGAG ACGCCCAAGTGTTGCTTGAAGAGTTCTTGGAGCAGGTAGTCCCTGCCTGCTCTTCTCGGA GGATGGATCAGAGGGGAGGAGGTGGTAGGACCACACGGGAGTCGGGGTCTGGGTTTAGGA TCTGGCCAAGAGGCTAAGCACCTCCATCCTCCATGGTTCAGAGACCCTTCAGCCACGTTC TTCAGTGGAGACCAAGATAGCAGAGGTTGGACCCTTGTCAAAGGCCACATGGGCAACGGG CAGACCCACGGCTGCATTGTGGGGAATGAGGGGTGCCATGGGATCTCCCAGGTCCCCAGA CCCCATTCTGGACTCCCAGGCCCCACCCTCCAGCGCCCTCCCCTCTCCTTTGCAGCCCGA GGCGCTGACCTCACCACCGAAGCCGACTCTGGCTACACCCCGATGGACCTTGCCGTGGCC CTGGGATACCGGAAAGGTCAGCCTGAGACACACAGAGCAGGGGTGGGGTCCCTTCCATAG GCAGGGTGACCATAAAGGGGTACATGGGACACCCCTTCAGTGGTCATACGCCGGCAGCGA GAGTGTGTTGACAGGTGTTGAGCACTGCTGTGTATCCCGCCTGGGAACATCCCAGTCCTG GCTCCTGGGGCTCCACATGTGCTGGGGTAGGGAGGACAATGGGTGTCAGTGGCTGTGGCC ATGATGGGGGACACATAGGCATGAGAGGCCGAAAGAGGGGCCTCTCATCAAAGAGCCCCA AAGTGGCCAACAGAAGTCAGAGAGGCTTCCTGGAGGAAGGTGTCTTAAGGTTGAGACCCC GAGAAGTGAGGTGGGCCCAGCCCTGGGATGGGGAGGTCAGGGAAGGATTCTGGGGGACCT GAAGGGAGGGAGAATGGCATCCAGGTGGGAGGAGTGGCCCCTGCGGAGGCCTGGCAGTGA GGACACCAAGGGGTAGGCGACCAGGCCATAGTGCACAGAGCCACAGAGGCCATCCCTCTC CGTGGCGGGCAGTGGGTTTGAACAGGGGCCATAGGCAGACCCCAGTTTGACTCCATTTTC TCTGTCACAATGGGACCCCAACTTCCCCATCCATAAAATGGGGAGATCCCAATTGAACCG ACCCCCTGGGGTCATGGTAGAGATGGGGTGCTTAGGAAATATCCCCCTCCTTCCTTCAGA GTTTTACTGTGTTTGGGACAGAAATCATTCCTCTTCCCTCCTCATGTTTTCGGGGGGTTT GTTTTTTTGTTCGAGGCAGAAAGTCTTGCTCTATCACCCAGGCTGGAATGAAGTGGTGCA GGCACAGCTTACTGCAGCCTCGATCTCCCAGGCTCAAGTGATCCTCCCACCACAGCCTCC CGAGTAGCTGGGACCACAGGCATTCGTCACCATGCCTGGCTAATTTTTTGTTGTTGCTTT TTTTTTTTTTTTTTTTGGACATGGAGTCTCGCGCTGTCACCCAGGCTGGAGTGCAATGGC GCCATCTCGGCTCACTGCAACTTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCC TCCTGAGTAGCTGGGACCACAGGTGCACACCATGACGCCCGGCTAATTTTTATATTTTTA GTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTTGTGATCC GCCTGTGTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCTGGCTGTG TTGTTGTTTTTTTAGAAGAGACAGGGTCTCGCTATGTTGCCCAGGCTGGTCTCAAACTCC TGGGCTCAAGTGATCCTTCTTCCCCAGCCTCCTGAGTAGCTGGGACTACAGGCATGTACC ACTCTACCCAGCTAATTTTTAAAATCTTTTTTATTTATTTTTTGAGACAGAGTCTCGCTC TGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCTGCCTCCCAG GCAAACAATTCTCCTGCCTCAGCCTCCTGAATAGCTGGGATTACAAGTGCCTGCCACCAC ACCTGGCTAATTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCGCTCTTGTTG CCCAGGCTGGAGTGCTATGGCGTGATCTCGGCTCACTGCAACTTCCGCCTCCCAGGTTCA AGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCATGCC CAACTAATTTTTTGCATTTTTAGTAGAGTCAGGGTTTCTCCATGTTGGTCAGGTGATCTC AAACTCCCGACCTCAGGTGATCCACCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGC ATGAGCCACCACACCCGGCTGCACCTGGCTAATTTTTGTAGTTTTAGTAGAGATGGGGTT TCATCATGTTGGTCAGGCTGGCCTTTCCTGACTTCAAGTGATCCACCTACCTTGGCCTCC CAAAGTGCTAGGATTACAGGTGTGAGCCACCAAGCCCAGCCTAATTTTTAAATTTTTTTG GTAGAGACAGCGTTTTGCTCTGTTGCCCAAGCTGGCCTCAAATTCCTGAGCTCAAGCAGT CCTCCCCACTGGACCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCATGCCCAGGCT CATCTTTTCATGAAAGTCACAATTCACACATTTTGCTTGGTAGGAAATATTTTTATATTA ATTCTGAAAAGCTACAAAAGTGCATTTTTACAAACTTAGGGGAAGTTGAGGTTCCTGGGG TGAGTCCTCGGTTCTCCCAGCTTTGCTCTGTAATGCAGGTCTCTGCAAGGGTCCCTGTTT GTCCCCTAAGGGGAGAGCGCAGGTTGGCCTGTGCCTCCACCCCACTCCCGATTCAAGCTC ACAGCCCACCTTTTCCCTGCCCCATCTCAGTGCAACAGGTGATCGAGAACCACATCCTCA AGCTCTTCCAGAGCAACCTGGTGCCCGCTGACCCTGAGTGAAGGCCGCCTGCCGGGGACT CAGACACTCAGGGAACAAAATGGTCAGCCAGAGCTGGGGAAACCCAGAACTGACTTCAAA GGCAGCTTCTGGACAGGTGGTGGGAGGGGACCCTTCCCAAGAGGAACCAATAAACCTTCT GTGCAGAATGA OMIM ID 603200