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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTCH2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8643
Official gene symbolPTCH2
Full namepatched homolog 2 (Drosophila)
Aliases,PTC2,
Gene summaryThis gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.
LocationChromosome: 1   Locus: 1p33-p34
Gene position45308616 - 45285516  Map Viewer
Gene orientationminus
Gene size23101 bp
Gene sequence
OMIM ID603673