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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LAMTOR3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8649
Official gene symbolLAMTOR3
Full nameMAPK scaffold protein 1
Aliases,MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3,
Gene summaryThis gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q23
Gene position100815703 - 100799495  Map Viewer
Gene orientationminus
Gene size16209 bp
Gene sequence
OMIM ID603296