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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDE5A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8654
Official gene symbolPDE5A
Full namephosphodiesterase 5A, cGMP-specific
Aliases,CGB-PDE,CN5A,PDE5,PDE5A1,
Gene summaryThis gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q25-q27
Gene position120549981 - 120415550  Map Viewer
Gene orientationminus
Gene size134432 bp
Gene sequence
OMIM ID603310