Entrez gene ID | | 8664 |
Official gene symbol | | EIF3D |
Full name | | eukaryotic translation initiation factor 3, subunit D |
Aliases | | ,EIF3S7,MGC126526,MGC17258,eIF3-p66,eIF3-zeta, |
Gene summary | | Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.1 |
Gene position | | 36925277 - 36906897 Map Viewer |
Gene orientation | | minus |
Gene size | | 18381 bp |
Gene sequence |
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OMIM ID | | 603915 |
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