Entrez gene ID | | 8697 |
Official gene symbol | | CDC23 |
Full name | | cell division cycle 23 homolog (S. cerevisiae) |
Aliases | | ,ANAPC8,APC8, |
Gene summary | | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q31 |
Gene position | | 137549032 - 137523337 Map Viewer |
Gene orientation | | minus |
Gene size | | 25696 bp |
Gene sequence |
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OMIM ID | | 603462 |
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