Entrez gene ID | | 8714 |
Official gene symbol | | ABCC3 |
Full name | | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
Aliases | | ,ABC31,DKFZp686E22157,EST90757,MLP2,MOAT-D,MRP3,cMOAT2, |
Gene summary | | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q22 |
Gene position | | 48712218 - 48769063 Map Viewer |
Gene orientation | | plus |
Gene size | | 56846 bp |
Gene sequence |
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OMIM ID | | 604323 |
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