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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRADD (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8717
Official gene symbolTRADD
Full nameTNFRSF1A-associated via death domain
Aliases,Hs.89862,MGC11078,
Gene summaryThe protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q22
Gene position67193812 - 67188088  Map Viewer
Gene orientationminus
Gene size5725 bp
Gene sequence
OMIM ID603500