Entrez gene ID | | 8725 |
Official gene symbol | | URI1 |
Full name | | chromosome 19 open reading frame 2 |
Aliases | | ,C19orf2,NNX3,PPP1R19,RMP,URI, |
Gene summary | | The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q12 |
Gene position | | 30433425 - 30506616 Map Viewer |
Gene orientation | | plus |
Gene size | | 73192 bp |
Gene sequence |
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OMIM ID | | 603494 |