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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAM15 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8751
Official gene symbolADAM15
Full nameADAM metallopeptidase domain 15
Aliases,MDC15,
Gene summaryThe protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21.3
Gene position155023762 - 155035252  Map Viewer
Gene orientationplus
Gene size11491 bp
Gene sequence
OMIM ID605548