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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PABPC4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8761 Official gene symbol PABPC4 Full name poly(A) binding protein, cytoplasmic 4 (inducible form) Aliases ,APP-1,APP1,FLJ43938,PABP4,iPABP, Gene summary Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 1   Locus: 1p32-p36 Gene position 40042521 - 40026485  Map Viewer Gene orientation minus Gene size 16037 bp Gene sequence >PABPC4:complement(9998403..10014439):Length=16037 TTCGACCAGCAGCGCCCGGGGCGGGCGGGTATAAATGGAGCGGTGGCTCCCTCGGCCGCC TCTCTCCGCCCCGGGTCGCTGCCGCCTCCGCCGCTTTCGGGCTTCGCAGCCTGAGGAAAA AAAGAGAAAAAGATAAAAAAAATCTGAAAACGCTTCAAAATCCTGAAAAAAAAAAAGGAA AAGAAAAAACGAATCCTCGGAGAACCCGCGGGGAAGTCACTTTCGTACGCTTCCGGCCTG CCCCGCGCCCGCCGCCGCAGCGCTTGGCGTCCGTCGGTCTCCGTCCGTCGGTCCGGGGGT GAGCCGCCCGCCCGGCCCGCCGTGCCCTCCCCCCGCTCGGGCCCCGAGCCCCGCGCCCCG CGCCTGCCCCGGCGCACCACGTGTCCGTGCTGCCCTTCGCCGCCCGCCCGGGGCTCGCCG AGTCGGCGCCCACAAAGATTTGGTTTCCCTCTGCCCCGGCGGTTGTAATCTTAAACCGCC GGAGCCCGAGGCCTATATTTATAGAGAAACGCGTGTCCCCGAGGCCGCCGTGGGCAGCGT CCGGTCGCCTCTTAAAGGATTTTTACCCTTCGGAAGGGGATTCCCCGTTTAATTTTTTTC CTACTTTGATTTTTTGAAATTTGGAGCTTCGCACCAGGACCGCGGAGAAGTGCAAAGTCG CGGGGAGGGCCGTATTGTGCGGAGAGCCTTTTGTCTGCGGTGCTGCGGCCGTGGGAGCCG GCCCCCGCCTCCCGTTTCCGTCCCGTCTCCAAGCCCGCCGACTCCAGCTCGTCCTCGCCG CGCCGGTGCCACCTGTGAGCCGCGGCGCGGGCCCGGGCTCCGAAGGCGCCCCTTTGTCCT GCGGCGGGCCCGATAAGAAGTCCTCCTGGCGGGGCTCGGGGTGGTGGGGGGCGGGGAGAT GAACGCTGCGGCCAGCAGCTACCCCATGGCCTCCCTGTACGTGGGCGACCTGCATTCGGA CGTCACCGAGGCCATGCTGTACGAAAAGTTCAGCCCCGCGGGGCCTGTGCTGTCCATCCG GGTCTGCCGCGATATGATCACCCGCCGCTCCCTGGGCTATGCCTACGTCAACTTCCAGCA GCCGGCCGACGGTGAGTAGAAGCTGTGCCCACACGTGCGTGGGAGCCCGGAGGACCCCGG GAGTCGTCTTCTGGCAGGGCCCTCCTGCCGAGGAGGGCGGCATCACGACAGCATGTTGCC ACCGAAGCTGGGAGCAGGGTGCGGAGATTGAGAACGCGGACCTGGCATCAGATGACTCGA GTTTCAATCTTGTTTCTACCACTTGCTAACTGGGTGACCTTGGGCTACTTATTAGTGTTG CTGGTAGTGGGGTTGGAAACCAAGGAGACTGTAAAACAGGATTAGAGTGAAGCCACTGGC ATTCCACTGCGTGTGGTCCTTGTCAGTGGGGCTGGGCTGTTAGAGATCCTTGCTTGTGCC CCTCACAGGCTGGCCAAAAAGGCGGGACGTTTGAAACACAATTCCCCGCGAAAGTTTTAC ATTGTAAAGCTCCTGCCCGCTCCGCCACCTTTACTAACCTTGACTACCTGATGTTGTGCT GATAAAGGATCAGTCAGGGCAGGCAGGAAGCAGGGGGAAGGTTTCTGTGCGTTAAACTTT CGCAGAGACTTAGGTTAGTGCCACAAAAGCTGCGTGTGCCAGGCCACCTCCTTGGTCTGT GTGTTTGCCACTGGAGTGGAGAAGTGCTTTACTCTGGACAAATGGTATCCAGGCTCTGTG CTGTAGAGTGTCGTGGAGGTAGTTTAGGGAAGCGTCACTTGAAAATCTGGTGTCATTTGT CACCTCAGCTGTAACAGTGCTTTGCACTAGTCAGAGCCCTTTTATTTCATCTAATCTGAA GAAAATGGGACTCCTGAGAAGGAGAACGAATGCAAAAAGTTGGAAGCCAAGTTAGGACTC CCAGCACAGTGCTCTGCCACCTCAGATTGTGGCCTTAGCGTGGAGCATGGAGAGAGGTAT GCTGCAGGCGTGGCAGGAGGGAGGCCAGAGGAAACCTGATCAGAGGCTGCACGTGACTCC AGATTAAAAGGGAACAACTGCAGAGATCATTACTGGGAGAAACAAGCCATTCTATGGCAA AGCATCTCCAGGTCCCTAGTTTTGGGGTCCCCCCTTTGTTTTCTGTCTGAGGCCCAGAGT TACTACCTGCCCAGGTTGCGGCTGAGACCAGAGAATTGGACATGTTGAGAGGGACTAGGT ATTGCTACTGTCAATCCAGTGTGCTCCAAGCTGAGTTCTGTCCATGGCCATAGGAGCGCA AAGGTAGCTGAGTGTGGTCTTTTTAAGGGATAATGTACCACATTAGCTGTTGTCTGCCTT ACTGACTTTTGAACAAAAGTCGTGTCACTTAGAGATAGCAGAAGCTATTGGTCAGTGTGT CTGCCAACACATACTTCTGCAGGACTTCTCCCTGCTATAAATAAGTGCAGCCAGATTTGT CAGACTAAGCCGGCTTGCCTTGTGCAGTGCTGTCTGGAAATAGACGAGGAGCTGTTGTTG AAGTGGGCTCCTTTACTGCTAATTAATGAAATAGTTTGCGATCCCAGCTATCTATCTCTG ATAGCCATCACAAGCAAAGTCCTCTTTCCCTGGACTGTTCCTGACTTGGATCGGTCTTGT CATCTCCCCTTTTCCCAACTACCCCCCACACAGATGAGGCCCACCTTCTGAAGGGGGTGG GGAAAGTTGTTGGAAATAATGAGTGAAAATAAATTCTCCCGGCTAATGAAACAGTTGAGC TTGTGGAGCGGCAGAGTTGGGGAATTTTGTCCCCCCTTTAAGTGAGATGTTGTCCTGAGG CAAGGAGCAGGTTCCACTGCTCTGACCCTGTCTAAATCCCCTCATGGAGGAGGTTCTGGG TGATGTCACCGTTAGGAGATGCCATCATAGCCTTAAGGAAAAGTGGCCACCAGATCTGGG CATCCTTGTTGCGATTAGTGATGAGAAGTGTTTTGGCTGGCAGGTGGTGTTATTTTTTAG CTTTTGGTTCTTTTTGTTGTTGTTTGTTTTGAGACACTGTTTCACTCTTGCTGCCCAGGC TGGAGTGCAATGGCGCGATCTCAGCTCACTGCAACCTCTGACTCCTGGGTCCAAACAATT TTCCTGCCTCAGTCTCCTGAGTAGCTGGGATTACAGGCACCCGCCACCATGCCCAGCTAA TTGTGTATTTTTAGTAGAGATGGGGTTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCC TGACCTCAGGTAATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGAGTGAGCC ACCATACCCAGCCCAGCCTTTGGTTCTTTAAATTGTCTCTGGTGTACACACGGACTTGGT TGGGAAGCTAAGGAAGCATTCCAAGGTGTTGGATGGGGAAGTTGGTTGAGCACCCAGGGT AGCTGAAGTCCTAGAATTCTACAGAACTTCCATTAAGGCTTCAAAAGGTGGGTGCAGGGC CTGCCATCTGCGCACTGTCTACTTAGGCAGAAGGTATGGTGGTTTTATCCTTGTGATAGT ACAGAGAACTTTTCCATGTGTGATCAGTTGTGTCCATTTTGATGACTGATGCTTTTTTGT TTAAGTCAATTTCTGTTCTCAGAAATTGAAAATAAACTGGACTGAATTCTGAATTCAGGG ATAGCACCTTTTTTTTTTTTTCCAGATCATTTGCTTTACAGGTTTTGTCACTTGTCTCCA TAGGTGGATTGCAGACTAAATGACTTGATAACTTTGATGCAATACCTCACTGAAAAATAA ATCAGATAATCTAGTATTAGTTTCGTAATTACTAGCTAGCTGCACAGCTTAGTTACCCTA AACATAAGTTTGTTCATTTTGTAAAATGTATAATTTCAGCTGTCCCACCTGAGTCATGGT GGGTGGTAGTCTGCAAAGTCTCTTCTAAGTGGTAAAGCTTAGTCAAATGTGAGGTATTAT CACTGGATCTTGGTGTCATTAAGGCCATTTAGATTATCTTTACTTGTGGCCCCTTTATCC AACAAGGGCACAGACCCAGAAGGGTGTTTAGACTTCTGTCATGAAGTAGAGTCATTAGCT GGAACTTATGCTTCCCTTACTAACAGTGCAGGCTGGAGGAATCTGATGCCCTTTTATTTT AATAGAGTTGCCTTTTATCAAGAGTGATTACCTTGAAAAGTCCTGGAGTAATCTGTTCTT AGGCTGTTGGCCTGTGGGAGCTGACGTTTTCTCTCCTTATTGAAATGTGTTTCTCTCTTA CAGCTGAGCGGGCTTTGGACACCATGAACTTTGATGTGATTAAGGGAAAGCCAATCCGCA TCATGTGGTCTCAGAGGGATCCCTCTTTGAGAAAATCTGGTGTGGGAAACGTCTTCATCA AGAACCTGGACAAATCTATAGATAACAAGGCACTTTATGATACTTTTTCTGCTTTTGGAA ACATACTGTCCTGCAAGGTAAACATTGATTAAATGATTTTAGCAGAATAATTAATTGATT CTTGAAAACAAGATAAATACCAAACAGAGAACTATCTTGGAATTGGGGAACAAGATATGG GAATTTTCAAAATGCTGGACATGGAATCCTAAAAGTTCCCATAGGTAATCTCAGGGCCAT ACCCAGCGTAACCAGCACACGCTTTCATACCCTTGTTCTTTACTCAGCCTGAAATATCCT TCCTATTCTTTAGCTTTGGAAAGCCCACGTTTTTCTTTTGGGATGGGGGAAAGTAGAGGA CCAGAGAAGTGTCTCTAGTCTTGAGGAAACTTAATCACTTTAGAAGCATAAATTCACTCT ATTCCTTCTACGTATCTGTTCTATGCTGAGCACTTTAAAACTTAAACGGTGGTGGTGTAT ATGTTTAATGCCATACTACACTGAAAATCTGTTGTGGCCTTGGAAAATGTTTTGTTTTCT GCATCACCGTGGTTTGCACCCAGATCTCTTAAAATGTGTTGTTGTGTTTTAAAGAGACAG AGTCTTGCTCTGTCTGTCACCCAGGGTGGAGTGCAGTGGTCTAGTAATAGCTCATTGTAG CTTCGACCTCCTGGGCTCAAGCCATCCTCCCACCTCAGCCTCCCAAGTAGCTGGAACTAC AGGCACGTGCCACCACACTCATTTAATTTTTTTCTTTTTTGTAGAGACAGGGTCTCCATT GTCCAACGATCTGGCTCCAACGATCCTCCTGCTTTGGCCTCCCAAAGCATTGGGATTACA GGCATGAGCCACAGCACCCAATTTTAAGTATTTTTTGTTTGTTTGTTTTTGATAAAAATA AAACATTTGGAATAGAAGCATCTTAGTAGGGCTACCTTTGTAAATGGAACACTTACTAGG CACCTGGTGCTGTGCTAGGTGTTAGAAAAATTATACTGGTGTACTTGACCACCATTGGCC ATGGATGGGCTAGAGTCTCCTCAGGCACAAGATACCCTGAGGTTCTCATGTCTCAGGAGC TGGCCAGTTCTGCTAAAGTGGTCCGCCTTGTCTTTGACAGGTGGTGTGTGATGAGAACGG CTCTAAGGGTTATGCCTTTGTCCACTTCGAGACCCAAGAGGCTGCCGACAAGGCCATCGA GAAGATGAATGGCATGCTCCTCAATGACCGCAAAGTGTGAGTGTCCCAGTCCGGAGCAAC AACCATCGCATGAGCCAGCCGTGGCCCCACCTCGCTATTAACTGGCACACACAAGGCGGC TACTGGTTCTCGGCCCAAGTGTGGCCTGCTCCTACCTCTCCACTCCAGGGCTGGTGAGTC TCCCTGCCTGAGCCGTGGCAGCCCTTTTGACTCGCCAAGGTGGGCTTCCTGCCCAAGCCA TGGCCTGCCTGCCGCCTCTCCCTTAAAGGCATCTGTCTGTGGGTTTTGTGAGCATCAACA ACTGGGGCTGGCTGGAAAGCAGCTCTAAGCTCACTCTGAGTCGGGGTCTTGGCCAGCGGC AGAGTGGAGAGGGCCCTGGACTGACCAGGAGCTGTATACTAGCAGTGTGACCTTGGCTTT CCTGTGATTCAGGTCTGTCCATGGGTCCCTCGCTAGTGGTTGATGCCAAATTGTCCCCGC GGTTCTCCATTTTCTAACTTATGACTCAGTGACCTAATACAAGGCTGGCTCCACAGTAAT ACTTGGTGACAATGAAAAAATCCCATCCCTTTGCAGAAAAACTTCATAACAGACCTTGTT GCTTTGATGTGGTTGTTACTGTAGAATGCAGAGAGGGGGAACTTACCAAAGCCATATGGG GAGAAGAAGAGACAATAAGTCTTGGCTATTACAAGCCAAAATAATTTTTGTCCTTTGTGT CATTCAGTATGCCAGAGGATGGGTTATCTTTATAATGTCTGTGTGTGCAGTGGTTGATCT ACAGATATCACTAAAAAGAAATACAAAAATGTCAGTGCATGGATAAATTTTCTTTTAAGT ATAACAGACCAAAATAAATAAATTTAAAAAGCAAAGGGTGCCCCTTCACTCCAACAATCT CATATCTAGGATTAACCACTGTTAACAGTTTGGTTTGTATCCTTCCAGACCTTTTCTATG CATTTACATAGTTGCACAGAAATGAACATTTTAAAAACATGGCCATCAGGTTTCTTCATG AAGGCAGTGTGATGTGGTAGGAATAGCCCTGGTCTAAGCCAGGAGCCCTGGGGCTGGTCC TCACAGGATAGTCCTGCCTTTTTCTCTTTCTGCTGGGGACTTGGGGTATCTCTGAGCCTC CTTGGTGGTGGATGGGGATCTCGTGTTTTAACCTCTCCTGTCAGTCTTTAACCTGTATTC CTTTGGGTCCCTGGACATCATGTTTTATTCCTCTGGGTAATTACTGTTCTTCATGGTTTC ATTTTAGATTTGTGGGCAGATTCAAGTCTCGCAAAGAGCGGGAAGCTGAGCTTGGAGCCA AAGCCAAGGAATTCACCAATGTTTATATCAAAAACTTTGGGGAAGAGGTGGATGATGAGA GTCTGAAAGAGCTATTCAGTCAGTTTGGTAAGTTGGGGTTCCTTGTCTCCTTTCACAGTC TACCAGACCCATCTGTTTTTTCTTAAGAGATGAGGGCACTGCTCCAGAGATTTGCTTCAA GTGAGTTTCCAGAGGGAAGCCTTCTGTTCCTGAGCTGTGCTCAAGATGGTGTTACTAATA GTTCTGTCCTTTGGTAATAGGTAAGACCCTAAGTGTCAAGGTGATGAGAGATCCCAATGG GAAATCCAAAGGCTTTGGCTTTGTGAGTTACGAAAAACACGAGGATGCCAATAAGGTGAG TATACCACAAAGATTGGGAAAAGCTTTTAAGAGGTTGCCCCAGAGTATGGGTAGGGTCTT GCTAGCACCTACCTAGAGCTGGGACGGTCTGAGTATCTGGTAGTAGATGTACCATTACTA TACTCTGGGATCATCTTCCTGGGTTCCGCATGTTAACTTCATGTAGGTGTTTACAAAGCA CTTGGCACATACCTGTCACCTCAGCTATCAGTTGTTGAAAGAATAGGACAGACGTTTGTT ATGCTGCAAAGGTGAGAGAACTAAAGCCCAGTGAGTGCTGATTTGATAACAGCACGGCAG CTACTTGTGGGCAAAGCATTGTGCCAGACCCTCAATATTTATCACTTAAATACCCACAAA AGCACCTGCAGAATTTACTGGCAGCCGGAATATTATATCGCCCTAGGCTCATGTCAGCAC ACTTGTGTTTATACACCTGTACTATTTCTATATTATCTGGATCAATAACCCATTTAAATA TTAACCTCACTTTACAGATGAGGAAGTTTGGATTTGTGTGACAGACTTCAGAGGTGGAGT GAATTTAGTTTTTAGTCCTATAGTAGAAAGAATATTTTTTGGGACTTAGACCTCCAGAAT AAGACCCCATCGCTGCAACTTTATTTTAAAGACATATTTTTCCTCTCTAGGCTGTGGAAG AGATGAATGGAAAAGAAATAAGTGGTAAAATCATATTTGTAGGCCGTGCACAAAAGAAAG TAGAACGGCAGGCAGAGTTAAAACGGAAATTTGAACAGTTGAAACAGGAGAGAATTAGTC GATATCAGGTAAGGTGGTCTTGGCCCAGCCTAGCAATGGGATTTGCTGTGAAATATTTGC AGAACACCCCTATGTTTAGCGGGCTTTCTTTTTGAGGACTTGGAGTGTGTTCTTCTTCCC ATTTTACCTAAAAAGATGAGGTTTAAAAGGATATATACCTACTACATATGACTGATTATT ATAGAACCAGAAACAAGAGATGGGTTTATTCATCAAGAAGCTCTCTATTTTGGAAGCCTC AGCCTGTTGCTTTTAGCCATGTAGGTTCCTTTTACTTAAATGAGACTCCTTTGTTTGGCA TGGCTTCAAGAAGACCCCTGCTGGGGTGGGTGAGTGGTCACCAGAACAGCTGTGGGGAGA GGTGACAAAAGGTGAGTGCACTGATGATCCTGTCAGTTTCAGGGCAGTAGTTTCACAACT TTGGACTTGCATCAGATTCATCAGCAGAGCTTGTTAAAACAGATAGCTGGGCTCCAGCCC CAGAGTTTTTCTTATTCATTGGGTTTGGGGTCTGGCCTAAGAATTTCATTTCTTTCTTTT TTTTTTTTTTTTCTTGAGACAGTCTCGCTCTGTCGCCCAGGTTGGAGTGCAGTGGCACAA TCTCGGCTCACTGCAAACTCCGCCTCCCGGGTTCGCACCATTCTCCTGCCTTAGCCTCCT GAGTAGCTGGGACTACAGGCACCCGCCACCATGCCTGGCTAATTTTTTGTATTTTTAGTA GAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATTCGCC CGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGTCCGGCCGAGAAT TTCATTTCTAACAAGTTCCCAAAGATGCTGGTGCTCCTGGTCTGGGGCCACCCTTGGGGA ACCACTTTCTTAGGGAATATTTGTGATATAGAAGTGTAGTTAACAGTGATCTTTTTCCTT CAGGGGGTGAATCTCTACATTAAGAACTTGGATGACACTATTGATGATGAGAAATTAAGG AAAGAATTTTCTCCTTTTGGATCAATTACCAGTGCTAAGGTATTATACTGCGATCTGGGG ATTGAAAGCAGTGGTATTCCATTATAGGCTTATTGGCATTTGTCCCATTGAAGGAATAGC ATTTAAATTATGTTCATTTCTGAAAGTAGCTACTACGTTTTTCTAGCAAAATTTCTGGAT GCATTCTGGAGAATGACATTTCATTAGGTTAACATTACACTGTTTCCCAAGCACTGGAGT CTGGAGAGGAATTTGACCCAGCCCCTCCTTGCCAACTCAGAGCACCTGAATCTTTCCCAT TCCTTGCTGCCTCGTGCCGGTGTGGGGACAGATGGTGCTACAGAATGAGCAGAGGAAATC CAGACAGGTTGTTTTCCATTTGTCTTGGGGCCTGTCTCTACAGCTCTGCCACATTTTCTC CTTGAGAATGAAGGTATTTTGAAGATTTTGGAGGTGGGCTTGGGAACTTCTACCCTGGTC TTAAAAAGAGAGGAAAGGGGAGTGGAAGGTTTTTCTATGTTTCGTAGTGTGCATCATTTG CTTGATTTTCTTTGATAATCATATCAACTAAGTTAGCAGGGTAAGTAGGAACCTCATTTT AAAGATAAGGAATTTTAGTCCTTGAACAAGAGAATGCTGACTACATGGGGATGGTGTACT GCTTGTCCTTGGCACTTTGGGAGCAGGATGGAAACTGGTGCCATCTGAACATTTTGAGTT ATGGCCGGATGCAGACGCCGGTCTTGCTAAACAGGTGTACCAGATGCCACAAAATCCTTT AGTTGATGAGAAGGGAAGCCACGTGGGCTGGTAAGGGCTTAGTGGCCCTGCCCTGGCTCT TAGTGGACTTTGCTCCCAACCTGGGAATGTGGAAAGCAATGTTATCAGTTGTAGTAGGGA GTTGGCCAGAGGCCAACTGTGGGTTTGCCCAGTTCTTACCCTTTCGTTTTTGCTATGACC CCCCCCTTGACTGGCCCTCATCAGTGTAAGGAGTGATCTTCTATCCTTGCTTATCTGCCT AGTAGTCAAGTTGGCATTTGTTAAGAGAGCAGAAGAGCCATACCTTGAATTGTCCCCATT TTCATTATGATGGTGTGGCATTTTTATTCACATACCTTACTGGCCCATCTCATTGGTAGA GAGTTATGGAGTGATGCACTTCTTTACTTCCCTATCCTCCACTTCAGGAGGCTCTCTGGG CCATTAACTAAGACATAAAACAATGACAGTCACACCAGAGAAGACAGTGAATAACCTTGT CTATTAGGAAGAATGCCATTTGTGAATGATGAACTTAATGTGGGAAAAGACTGCCTGAAC CAGTAGACCTGTGGTTTTGTAGCTGTTTGGAGTATTTCTTGGAAATTGAGCCTCAGGAAG GCAAGTGAGACTAGAATCTAGGCTGCCTATCTCTGAGCTGGTCATCTCATTGAATTAATG GTGGCAGTCATTGGTTACCTGAACATTTTAGGACTCCTGTCCACACGTGGTATTCCAAAA GTGTTATCCTGACGTTGGTAAGAGCTTGTTAGAGTTTGTCCACCGAGGTCTTGAAGCATA TGAGATATGAAAATAAATTGCTCAGTACTACTCTCAAGATGTTTTGTGGTTACCCGGAGT AGCTATCCACCAGGTATCAGGAAACATCTTTGAGTTCCTGGTTTTATTATTAGCCATATC ATAGTGTTTCAGAACTTTAGCATCACCTGGGGACTCAAAGAAAACACCTAGATACCTTAG AGGTTGTGACTTAGTTGGTCTGGGGTAAATCCTGTGCCAGAACCCTGACCTAGACTCAGT GACTGCAGCAGAACCCAGGCTTTCTGGTTCTTCTGAATAGTTCCCTCCCCACCCAGGGAC ATCCTTTTTTTTCCTATTTGTAGGTTTGTTTTGTTTTTTTTGTTGGTTTGGTTGGTTGGT GTTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGGAGATGGAGTCTCGCTCT GTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAATCTCTGTCTCCCGGG TTGAAGCGGTTCTCCTGCCTCAGCCTCCTGAGTAGCTAGGATTACAGGTGTGTGCCACCA CGCCCAGCTGATTTTTGTATTTTTAGTAGAGACGGGGTTGCACCATGTTGGTCAGGATGG TCTTGAATTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAG GCATGAGCCACTGCGCCTGGCCCTTTGTTTTTTTGAGATGAGGTCTCACTACATTGCTCA AGCTGGTCTCAACCTCCTGAGCTCAAGCAGCCCTCCCACCTCAGCCTTCCAAAGTGCTGG GATTACAGGCACAAGCCATCACACCCAGCCAGGGACACCTTATTTCTTAAGTAGCTGGTC TCATTTTGTAGGTAATGCTGGAGGATGGAAGAAGCAAAGGGTTTGGCTTCGTCTGCTTCT CATCTCCTGAAGAAGCAACCAAAGCAGTCACTGAGATGAATGGACGCATTGTGGGCTCCA AGCCACTATATGTTGCCCTGGCCCAGAGGAAGGAAGAGAGAAAGGCTCACCTGACCAACC AGTATATGCAACGAGTGGCTGGAATGAGAGCACTTCCTGCCAATGCCATCTTAAATCAGT TCCAGCCTGCAGCGGGTGGCTACTTTGTGCCAGCAGTCCCACAGGTGGGTGTGCTGTTTG GTCACAGCTCTTGGGAACCTGCCGGCTGGCAGTATTCTGCAGTGGTTGGGGAGAGGGATT TTTCGTTATTAGAGTTCTAGAATGTCACAATAAGGACCCTTCAAGTAAAAATGAAGGACT TACCCATGGTCACAAACACACACCCACAGTGGCAGTGGTAGCATAAAACAGTCCCCATTA GCTGACCCCTCAGCTCTTGAATAGAAAGAACATTTAAATAATTAGCTTAGGTCCTGGTTA GTGAGATGAGATGAGATACTTCTCTAGGATGGGTTCAGTCCTTAAGGGGGTGTTTGGGTA TTCTTCTGTCTTACAGGCTCAGGGAAGGCCTCCATATTATACACCTAACCAGTTAGCACA GATGAGGCCTAATCCACGCTGGCAGCAAGGTGGGAGACCTCAAGGTAGGTGGTGGGGAAC AGTAATTGACAGCCCAGGATATACCTGTCCTGGTCTCCCCTGCCTTTCCTTCTTCCCCAC TCTGAGGCACAGCCTAGGTTCTGGTCCACATCACTTCTCAATGATGTGCAATTTTTCTCT TCACCAGGCTTCCAAGGAATGCCAAGTGCTATACGCCAGTCTGGGCCTCGTCCAACTCTT CGCCATCTGGCTCCAACTGGTAATGCTCCGGCCTCTCGTGGCCTCCCTACTACCACTCAG AGAGTCGGTGAGCAAACTGGCCTTTAGAAGTGTGGCCTGGGGAGGAGGGAGTCAGGATGA CTAGGCTCTGTCCTGGGTTGGTCAGTTTGTTGGGCTCGAATTTATCGAGTCCTGGTTCTG TAATCTTAGCTGTGTGCTTAGGTGGCCACTTCAGGAGCAGAGAAACAGTATGAGTTCTAG GTGTGTCAGTTGCTTTTAACATTCTTTGCTCATCGGTGACCTATGTGAAAAAGGTTAGTT GTAGAAGTTTGCTAGCTGGATGACCACAGAGGCAGCTTGTTCTTTTGGGTGGGGTGAGGA ATACAAGGAAACAGTGTATACAGAATATGTCTTGTATTCCAAGATGTGGAAAGAGTTGTA TGTTATCCTTTGGCTCATCCTCGAAAGTAGTAGTGGCCCCCTGTGCAATGTGTTGCGTAA ACGTGCTTTGAAATTTCTCCTTCCGTGGGACGTGGCCAGTTGGACATCTGCCGCCAACAC TGATGTGCATTTGCTGGTCTGTTGTAGGGTCTGAGTGCCCGGACCGCTTGGCTATGGACT TTGGTGGGGCTGGTGCCGCCCAGCAAGGGCTGACTGACAGCTGCCAGTCTGGAGGTGGTA TTGGATGCACACAGAAGGGGGAAAGATGGGATTTGACGGGTCTTTGCCCAGACTGATGGG CTTTAATTGTATTTGTTCTTTCCCTAAGGCGTTCCCACAGCTGTGCAGAACTTAGCGCCA CGCGCTGCTGTTGCTGCTGCTGCTCCCCGGGCTGTTGCCCCCTACAAATACGCCTCCAGT GTCCGCAGCCCTCATCCTGCCATACAGCCTCTGCAGGTGAGGTTCACCAGACAGAATGCT TAAAAGGATTTCCCCCATTTCCACTTGATGTAAAAGAAGCTGTGCTTTTGATTCCTTCAA CAGGTATTAAATGCCTGCTCTGTGTTATGACGCTATGTTCTGATTCACTGTCCCTGCCCT TCAGGGGCTCACTAGTGGGAAAGAAGGGGCTTAAAAGTGCTCTGCCTGATGCCAGTTCAC TCAGAAATGCCTCAGAGCGGGCAGCCAGTGCTTCCTCTTCTGTTTGTACGAAATAATGTG CTCATTCAGCTGTTTGAGCCTCCAGGTCACTTCCGCATCCAATGACCTATTGGATCCTTG GCTGCTCTGCAAGATGATTGGTACATTAATGCAGGAAATAACTTCAACTTACAGATCGGA TGTTCAGCTTCAAAGATGTAAAGTGTGTGTAGGAGGTGAAGGGGTTGAACCTAGAGCTTA GATTTTCTAAGCTGTAACTTGCTGTCTCTAGACCTGTGCTCTAGATGCAACTAGTTTGTT TCAGAGCCTAATAGCAATTTGCTGTGGAGGTGTCACCCTAAGCCTTCAGGCCCATAAGCT GCTTAGGAGATTACTCTTTAACTGTCCTGTCTCATACTCTCTAAGTTGGGGATTTCCTAG AACTTGATGCTATGTAAAATACCTTTTCTTTGCAAGGCTTTGACTAGCATTGACGTTGCA TGTTGACCGTTTTTAAGCATTTGATACAAAAACATTTGGTAGAATTAAGGTGATGTGGAA TGTAATTATAAATGTGTTGATATTTACTCCCTTTGATCCAATCTGCACTGAGATTTACCC TAAAGGAAAACTAATTTTCAGGAAAAGGTTATATACAAGTGTTTACCCTTATTTATATCA AGGCTTTTCATTCTTGAGTAACTTTGGGTGTATTAAGGAAATGTCAGAAAATGCTTGCCT AGCACTATAGGTTTGTTTTATTATTTACGTTTCACTTCGCTTTCTGATAGCATGCCATTT TCATTGTAATTGGTTGTGTTTATGTCCATACCACTCTGTTCCTCAACACACCCCTCAATC CTTCAAGGACTGAAATTAGTTCCTTTAGAGCAAGGACAGCCACCTCCTCTCCTCTTTCAC ATAGTCAGATGTTCAGATATTGAACAGGCACTCAACCACCATCAGGTGTTGTCCTTTCCT CAGTGCTAACCCACTGCCTTTCCTGGTTCCCAGGCACCCCAGCCTGCGGTCCATGTGCAG GGGCAGGAGCCACTGACTGCCTCCATGCTGGCTGCAGCACCCCCCCAGGAACAGAAGCAG ATGCTGGGTGAGTGACCCACTTGCTTGCAGAAGAAGAGGGTCCCAGAGCCTGATGCCAGC TAGGACACCAGTGTCCATTGTTTACTGGGATTTGATTTGTTTTTTTATTAACTATCCTCC CCATAGGAGAACGCTTGTTCCCACTCATCCAAACAATGCATTCAAATCTGGCTGGGAAGA TCACGGGAATGCTGCTGGAGATAGACAACTCTGAGCTGCTGCACATGTTAGAGTCCCCCG AGTCTCTCCGCTCCAAGGTGAGCTGGGGCTCAGACCCTGCAGCTTCAGTTCTCAGCTTGG GAAGACTGGGGGCAAACTTGGATGCCCAGGTGCAGCAGAAAGTGGGATCTGCTGCCCCCA GGACCCCTCTCGTCATGCCTTGACTGTGACTGGAGGCTGCAGTGGGTATTTGGGAAAGTA GTTAGCACCAGAAGCCTAGGGATCATCTGTACAGTTGGCTTTGGTCCACCACTAGGTCTG GGCACTGGGGAGGGGTGGAGTAGCTCTCCTAGATTCACTGACCACCTGAAGATTTCTCGC AGGTGGATGAAGCTGTAGCAGTTCTACAGGCTCATCATGCCAAGAAAGAAGCTGCCCAGA AGGTGGGCGCTGTTGCTGCTGCTACCTCTTAGACAAGGAAAAACCGTATGTGTGGCTATT TTCATTTTTGTTCCTATGAGCATTGTTCCTATGAGCATTGTCTTTGTGGTTTGACCTGAG GTTGTATATATGCTCACTGCTTAGCTCTGGGAATACAATAAGTACAGTTAGTTACACGGA GTGTGTTGCAGGTGACTTCTTATCATGAGGACTGTGGACTTTGTCTGCAGGAGCTTGAGT GAATAATAAAACTAGTACTGGTTGATGGTTGTAGGTGTCTCCAGATAGGGAAAGAAGAGA CAGTAAAATAAGCTAAGGAAAAAGCACATGGTAAGGACCAGAGCTGGTGTGTTGGGAGGG TTGACTTGGCATAGTCATGACCCTCTTGTCAAGGGCCTCAGGAGCCTTGTCATCTAGTGG TAAAGACCAGAGATGCTGCTAAATGTTGTACAGTACACAGGAGGACAGACCCAACAGAAT GTCCAAAGTGTCAATAGCACTGAGGTTGAGAAACTCTCTTCTAGAATACCTTCCTTTATC CACTATATGTTAATGAATCTAAATTATTTGATTATGCATTTATTTGTGTTGGTGCTTTTC TTTACAGGATTCAAAAGCCAAATAACCCCTTATGGAATTCAACTCAAGGTTTGAAGACTT CCTAGCTTGTCCTATGGACCTCAACACCAAGGATTACAAATTGCAAATTTAATAGGTCAT TTTGTATCAAAAGGTCAATTATGAAGCACCTAGAATTTTTCAATTATACGAATATGTTCT TTGGGTTCTGCTGTGGCCCAGACAGTGTTAACTTTTTTTTTATTGTGGGTTTTGATTTTT TCCCCCAGAAATTGGTTTTATTTGATGTACCCAAGTCTTACGTTTCCCAATAAAGAAAAA AAATCTCCATAAAACTG OMIM ID 603407