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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFRSF14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8764
Official gene symbolTNFRSF14
Full nametumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Aliases,ATAR,HVEA,HVEM,LIGHTR,TR2,
Gene summaryThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.3-p36.2
Gene position2487805 - 2495268  Map Viewer
Gene orientationplus
Gene size7464 bp
Gene sequence
OMIM ID602746