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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SNAP23 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8773
Official gene symbolSNAP23
Full namesynaptosomal-associated protein, 23kDa
Aliases,HsT17016,SNAP23A,SNAP23B,
Gene summarySpecificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q15.1-q15.2
Gene position42787835 - 42825256  Map Viewer
Gene orientationplus
Gene size37422 bp
Gene sequence
OMIM ID602534