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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TNFRSF10C (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8794
Official gene symbolTNFRSF10C
Full nametumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Aliases,CD263,DCR1,LIT,MGC149501,MGC149502,TRAILR3,TRID,
Gene summaryThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq]
LocationChromosome: 8   Locus: 8p22-p21
Gene position22960327 - 22974950  Map Viewer
Gene orientationplus
Gene size14624 bp
Gene sequence
OMIM ID603613