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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARHGEF7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8874
Official gene symbolARHGEF7
Full nameRho guanine nucleotide exchange factor (GEF) 7
Aliases,BETA-PIX,COOL-1,COOL1,DKFZp686C12170,DKFZp761K1021,KIAA0142,KIAA0412,Nbla10314,P50,P50BP,P85,P85COOL1,P85SPR,PAK3,PIXB,
Gene summaryRho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q34
Gene position111767624 - 111958081  Map Viewer
Gene orientationplus
Gene size190458 bp
Gene sequence
OMIM ID605477