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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MCM3AP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8888
Official gene symbolMCM3AP
Full nameminichromosome maintenance complex component 3 associated protein
Aliases,FLJ44336,FLJ45306,GANP,KIAA0572,MAP80,
Gene summaryThe minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. [provided by RefSeq]
LocationChromosome: 21   Locus: 21q22.3
Gene position47705236 - 47655048  Map Viewer
Gene orientationminus
Gene size50189 bp
Gene sequence
OMIM ID603294