Entrez gene ID | | 8888 |
Official gene symbol | | MCM3AP |
Full name | | minichromosome maintenance complex component 3 associated protein |
Aliases | | ,FLJ44336,FLJ45306,GANP,KIAA0572,MAP80, |
Gene summary | | The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.3 |
Gene position | | 47705236 - 47655048 Map Viewer |
Gene orientation | | minus |
Gene size | | 50189 bp |
Gene sequence |
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OMIM ID | | 603294 |