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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MTMR3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8897
Official gene symbolMTMR3
Full namemyotubularin related protein 3
Aliases,FLJ32333,FYVE-DSP1,KIAA0371,ZFYVE10,
Gene summaryThis gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q12.2
Gene position30279158 - 30426857  Map Viewer
Gene orientationplus
Gene size147700 bp
Gene sequence
OMIM ID603558