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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PHOX2B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 8929 Official gene symbol PHOX2B Full name paired-like homeobox 2b Aliases ,NBLST2,NBPhox,PMX2B, Gene summary The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq] Location Chromosome: 4   Locus: 4p12 Gene position 41750987 - 41746099  Map Viewer Gene orientation minus Gene size 4889 bp Gene sequence >PHOX2B:complement(1449003..1453891):Length=4889 TTAAATTCTAATTAGAGATGCAGGAATCAATGATAGGGAGGTTGGACAGCTCAGTTCCCC AGTGCCAGCCCAATAGACGGATGAGTTATTGTCATGTAAAAAGCGCCAGCAATAAGACCA ACCGCTTTGCTATTGTCCAAGTGGAAAGAGCCAAGTTTATTATGAGGACTATATGCTCTA GAGACCTCAGACAAGGCATCTCATAGGAGGCTTTTTCATAAAACTAGGCTCTGCTGGTAG TAAGGAGGCCAGTTTGGAGGCAGGCGTTGAGCTGTGCACATCTCCCCACTCCAGCCACCT TCTCCATATCCATCTTTTATTTCATTTTTCCACTTGGCTGAGCCATCCAGAACCTTTTCA ATGTATAAAATGGAATATTCTTACCTCAATTCCTCTGCCTACGAGTCCTGTATGGCTGGG ATGGACACCTCGAGCCTGGCTTCAGCCTATGCTGACTTCAGTTCCTGCAGCCAGGCCAGT GGCTTCCAGTATAACCCGATAAGGACCACTTTTGGGGCCACGTCCGGCTGCCCTTCCCTC ACGCCGGGATCCTGCAGCCTGGGCACCCTCAGGGACCACCAGAGCAGTCCGTACGCCGCA GGTAAGGACCTTCAGCTTTCTCAGCGGAGGAAGCCGCCTTTCCGCCCGTATATAGGAAGC CTTGATTGCATTTGAAAATGGAAATGTGTTTAGTATTTACCAAACGAAATTTGCTTACAC AAATGAAAGAATTTATCACGTTAGAAGCGATTGCAGGGAGGGGTAATTCACTTACAGGGT TACACTATCCTAGTCACACCCGAACCGCCAACAAAATTATCTTAAGCTGCCAAAATGATA GGCATAATTTATTTACTTTGCGATGAGACGTAAAGCTTAGAAAATAATTAAATAACAAAG AGTAAAGCTCATTACTGGCAGTGTCTCTTTTTTTAAGAACCGACAGCGGCTCACACCTCT TTGGCTGGTCATTTTTATGATTATTTCTTTAATTTATTATTATTTTTTTGCAGCTCTTTC CCCCAACTTTTGAGCCGGGTCAACTTTCTGAGAATTGAAAAGTTCCCAAAGTGGGACTGT TTGGTAACTTCTTTCCTGGCTCCCTGATATTCCGACTGATGTTTTTGGATTTTTTTCCTC TCTGGTTTTTTCCTGCTGAAAGCACTATCTCAAGTCCGTCACATCGCGCTGTTTCAATCC ACCCAAAGGCGCTTGTGCCAGAAAGGACTCCGCCAAGCCCGAAGTTTGAGCCCAGGTTTC CGCAGATAACAAATTTCCTCGGTTTCTTCCCGCAGCTTCTCTCGGCAACTCTCTCGCGCG GGTGTAGGTAGCGGCTGCCGTATGACCTGACCTTGGAGTCCTCACATTCTAGCTCCACGG CCGGCGAGCTGCCGGCTGATTTGCTCACTTTCTGTCTCCTCTGTCATACTCTAGTTCCTT ACAAACTCTTCACGGACCACGGCGGCCTCAACGAGAAGCGCAAGCAGCGGCGCATCCGCA CCACTTTCACCAGTGCCCAGCTCAAAGAGCTGGAAAGGGTCTTCGCGGAGACTCACTACC CCGACATCTACACTCGGGAGGAGCTGGCCCTGAAGATCGACCTCACAGAGGCGCGAGTCC AGGTACGCGCGCCTGGAAACCGACCCCGCTCCGCCGCACTGGTCCGGGGAGGTGTGGGGT GAGGGGCGGCTGGTGAAATTCGAAGTCCTGGAGCCTCGAGTGAGAAGGACCTAGGGCCCC ATGGCCGATCAGAAATACTGGATTTGGTGTGGCTGTGCGTTCGAGAGAGGCTTAGAGCGC ACGCTCTTGGCATTTTATTTACAGTTGCGAAGTGTTTCCCACCCGAGCAGAGACATGGGG GGCCTTGGGACGTGGATGAGCGATGCAATTTCGGGGACAGGAAGTGCCTGTGGTGGAAGG TGTGCAGACTTTGCTCCCGTATTATAAGTTTTTCCTTCTCCCCTCCCGCCCCCCAAAAAA ATGCCTCCTAACTCAAGTGCTTTTAACCTGGCCCCATGGCATATAGGTTCATTTTCCCGG AAACTGTGACTTGCATCAGATTTGCAAAGGGTCTGTGACTTCATGAAGGTCAAGAACCAT GACTTACTCCAACCTGTTAAACACAGGTGCGCTCACGAGTTGGCCACAGCGCCTCTCTGG GTGAGCCCCCGACCGAGAAGCGGTGCGCACCATCGCACGCTCTTCCAGGCTCAAAGGCCG GGGATGGGCAGCGGAGCAAACCCAGAGAGGATCCCTTTTCCTTCTACCAATTAGAGTTTA ACTTTAGAACTTAGGCTTAGGGGTGAATGGCGAGCTCGGGGCTTGCTCAAGAAGCCGACT GAACAGAGGCCCACCAAAATAAGGCCTTCCCTTTTCGGGTCTTTCTGGGACCTGCGGCTT TTTAAACTCTGCCGCAAGCCTTCATGTCCCTGGCGTGCTCACTCCCCCTAAGAAAGTTTC TCCGAAAATGCACAGCAATAAGAAGCGGTAGACTTGGTGGATGTGCGCGCGGGGGTGATC ACAGCGCATGGGGAGGAGGGTGTTAAAACAAGCCGAAGTAGAACTTGGGCCACCCTAACC GGTGCTTTTCTTTCCCATTTTCTTCTTTCTCCCCCTGCTTCACCGTCTCTCCTTCCGTCT TGGGCCAGGTGTGGTTCCAGAACCGCCGCGCCAAGTTTCGCAAGCAGGAGCGCGCAGCGG CAGCCGCAGCGGCCGCGGCCAAGAACGGCTCCTCGGGCAAAAAGTCTGACTCTTCCAGGG ACGACGAGAGCAAAGAGGCCAAGAGCACTGACCCGGACAGCACTGGGGGCCCAGGTCCCA ATCCCAACCCCACCCCCAGCTGCGGGGCGAATGGAGGCGGCGGCGGCGGGCCCAGCCCGG CTGGAGCTCCGGGGGCGGCGGGGCCCGGGGGCCCGGGAGGCGAACCCGGCAAGGGCGGCG CAGCAGCAGCGGCGGCGGCCGCGGCAGCGGCGGCGGCGGCAGCGGCAGCGGCGGCAGCTG GAGGCCTGGCTGCGGCTGGGGGCCCTGGACAAGGCTGGGCTCCCGGCCCCGGCCCCATCA CCTCCATCCCGGATTCGCTTGGGGGTCCCTTCGCCAGCGTCCTATCTTCGCTCCAAAGAC CCAACGGTGCCAAAGCCGCCTTAGTGAAGAGCAGTATGTTCTGATCTGGAATCCTGCGGC GGCGGCGGCGGCGGCGACAGCGGGCGAGCCAGGGCCCGGGCGGGCGAGTGGGCGAGCGGG TAGGCCCAAGGCTATTGTCGTCGCTGCTGCCATGGCTTTTTCATTGAGGGCCTAAAGTAA TCGCGCTAAGAATAAAGGGAAAACGGCGTCGCCCTCATTTCAACCCCACTCCTACCCCCT TCCTCAACCCCCAAACAAAACAAACAAACTTCCCTGGCTTCGCACCTGCCTGGGGCCTCG CAGCGGGGCCAGGGCTCCGCCTGCTGATCGGGGGTTGTGAGCAGCGCGGCCTGGACGCGG GGCACTCTCAGGGGGCTGTGTCTGCGTGTCAGTTTGTGTCTGTCTCGGGGAATGTGTGTC TGTGGCCCAAGCAGGTGACAGGAAGAGATGGGGGGCCTCAACCAACTTAGTGACTTGTTT AGAAAAAAAAGACAAAAAAGTAAAAATAAAAACAAAAAAGTTGGAAGGCAGAAACCATTA AAAAACAAAAAGCCAACAACCCAGAAAGGTTTAAAAAACATAAGGAAAAAAAAGACAAAT TAAAGGAGGGGCTAGGGGAGAAGCTGCAGCTGGAGCTGAAGGCTCGATCTTGTGAACCCC TAAATCCGCTCCCTCCTAACAGCACGGATTCTCTTGGGGCTCTTCTTCAGGGAAGAGTAG GGACGCCGTTCCAGCCCCCCTTCCTATCGTGTCCTTGGGTTCGGGTCACTGCGGCGACGA CTTGCTCAGACTGTCCCGGCGGCCGGAGTGACTTTCTCGCACCCCCTTGCCTGTCCCACC TCGCTGAACACCATCCCGCCATTAGCGCATCGGAACCCCACACAGTTGCAACTCCCAACC CCGAATCTTTGCAGCCGTTCGGCCCTGAAAGATGCCCTATCCATGAGATGCCTTTTCATC TGCAAACTCTGCAAAATGTGTCTCATGTTTCGCAACTCTTTTTTTCCCCCTCGCTCCCGC CTACCCCGTCGGCATTTTCTTCTTCCACCAGCTTTTACTGAACTTTTTGGCACTGCTTTG GATTGGGGTCAATTGCAGTCCACGTAACTGGCTGCAGAGAAATCTACCGAGCAAGGAAAA GGCACACACACACGTTTGCAGGGGTGTCTCGGTTTGCATTTCTGTTGGAATGATCCGAAC TGGACTCACATCCTGTATGGTGGATGGACTGTATATTGAGGGTTCCATTCTTCGCGCAGT TTAGACATCTCTGTTTTGATTCTTTGTTGTTGTTTTTATTTTAAAAGGCACAAACTCTAG ATATTAGTTGAATGTTGAGGCTTTAACTTTTTCGGTGTCTTTCTACAACTGTGTTCTGTG ACTCAATTGTATCGTGTTAATATCAGTGCAGACTGTCTCCTCTACGTGACCGTATAATGT TTTTCTCTTCTTGTAGTCTCTATGGCGTGTCTTTATGGTGTAATAAGGTTCTCACGGGTT CAATCTTTTGTGTTTAGAGAGGCCACGGTTCAGACAATGGTATATATTTTTGTTATCAGG TGCATGTCTGTCTGATTTCTTTTTTTTTCCTGTTGGACTATGTTTGTGAACATAATTGTC ATAAGTTATGTTTCAGATTTTTGAATTTATTTATATGTGTTATAATGAATGCTTCTATTT AAAAGGGAAATATTTCTACATGTGCATATAGTTTTCCAAGAGTGTACCATTAACTTGATT GTTGATAATAAAAACAAAAAGCAAGTCTA OMIM ID 603851