Entrez gene ID | | 8997 |
Official gene symbol | | KALRN |
Full name | | kalirin, RhoGEF kinase |
Aliases | | ,ARHGEF24,DUET,DUO,FLJ12332,FLJ16443,FLJ18196,FLJ18623,HAPIP,TRAD, |
Gene summary | | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q21.2 |
Gene position | | 123813558 - 124440036 Map Viewer |
Gene orientation | | plus |
Gene size | | 626479 bp |
Gene sequence |
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OMIM ID | | 604605 |
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