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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARTN (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9048 Official gene symbol ARTN Full name artemin Aliases ,ENOVIN,EVN,NBN, Gene summary The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 1   Locus: 1p33-p32 Gene position 44398992 - 44402912  Map Viewer Gene orientation plus Gene size 3921 bp Gene sequence >ARTN:14370910..14374830:Length=3921 ACTGGCCGCTGAGAGAAGAATCGGGTGGAGCAGAGAGCAGCTGCTGCAGGGCAGACAGCC GGACCCCCAAATCTGCACGTACCAGCAGTCAGCCGCCCCACGCAGGGACCGGCTTACCCC TCGCTCCCCGCCCTCACTCACTTTCTCCCGCCCTCGGCCCGGCCTCCCAGCTCTCTACTT CGCGAGTCTACAAACTCAACTCCCGGTTTCCGTGCCTCTCCACCGCTCGAGTTCTCTACT CTCCATATCCGAGGGGCCCCTCCCAGCATCTACCCCCCTCCCAACCTCGGGGGACCTAGC CAAGCTAGGGGGGACTGGATCCGACGGGTGGAGCAGCCAGGTGAGCCCCGAAAGGTGGGG CGGGGCAGGGGCGCTCCCAGCCCCACCCCGGGATCTGGTGACGCTGGGGCTGGAATTTGA CACCGGACGGCTGCGGCGGCGGGCAGGAGGCTGCTGAGGGATGGAGTTGGGCCCGGCCCC CAGACAAGGCCCGGGGGCTCCGCCAGCAGCAGGTCCCTCGGGCCCCAGCCCTCGCTGCCA CCCGGGCCTGGAGCCCCACACCCGAGGTAAGCCAGCCCACTTGCCTGTTTCTGGTCCCAG CCCTGGATGGACGCTCTTGGGCTGGGGGAGAGGACAGGACCACCCCCCTCCTCTCCTTTC TTGCATCCTCCCTCTCTTGGGCCCTCGGCACAGTTCTCCGCCCCTCCCAGCCCCTCAGTC CCTCTTGTCGCTTGTTGGACTGTGCTGGCCTTGCCGGCCCACTGTAATGTGAGGCTCCCG CTGCCGCTACAGGGTGCAGACTGGCTGCCAAGGCCACACTTTTGGCTAAAAGAGGCACTG CCAGGTGTACAGTCCTGGGCATGCGCTGTTTGAGCTTCGGGGGAGAGCCCAGCACTGGTC CCCGGAAAGGTGCCTAGAAGAACAAGGTGCAGGACCCCGTGGTGAGTAGCGGGCTGGTGG ATGGGGAGGCAAGGGCCAGAGAACCAAATGGCCCTAGACCACAAGGAGGTAGGAGGCAGG GCCTGAGCTGCCCTCAAGAGACCTGCTCCCGGGCTCCCCCTAGCGCAGAGGGCTCCTAAG GCTGCCCTGCCTGCCTTTCCCTCCATCACGGACAACAGTCACTGGCCTGGCTCGGAGGCC TTGATTCCACTTAGCCAAGAGGCACACACCAGGACCTGGAGGACAACCCCGGGAAGGCCT GGGGGTCTGTTCCACAGGTGTGCAGGCATTCTGTGTGCTAAAGGATGGGGATGAGGGTGG TAGCTGGGACCCAAGAGGAGGCTGGCTAATGAGGACTTACGAAGGCTCTAGGGCCCCAAA AGGGTGTTTGGGAGTGCTAGCAGTGGGAGCTCAGGAAGGCTGGCTGGGATCAGGAACGAT GGCTCAAGGGGGAAACTTCTAGGAGCATGACTAGGCTGCCAGATCCATAGGAGGCTGGGA GGGGGACAGACCTAGACCAGCTCCCAGGGTGGCTCAGCTCTCAGAGACCAGGCTGGTATG GAAGCCTAGCTGGCCCTCCTGGGAGTGGCTCAGGCCTGAGTGTAGCTGAGGGGATGGAAA AGCCCACCCTGCTTGGAATCTGCAGGCTTGGCAGACTCTGCCCCCTTGTGGCCACAGGAA GCCATGACCCAGGCCCCATGTTTTCAGAGGGCCCATTAGCTCCCACCATCCCCCGGCTCT GTGGTCATCGAGGGACACCTATAGTCAGAGGAGAGAACTCAGGTGGCTCTGGGTCCAGAA CACAGTTCACAGAGGGGCGAGGTGAAGCAGCTCTGGGTGGGCAGCACAGGCTGAGGCTTG GGGCTCACTATCATTAGATAACTCTTAGAGTGACCAGCTAGCACCCTAATTCTTCTCCAG CCCTCAGCTTCCTCTCCGGCAGCCTGGGGTGAAGGCCTCTGTAGGACCAAGTGTGTCCAG CTATAACTCCTTCCAGCCACTTCTGGCATCTCCAGACCTACAACGCAGAGCAGGAAGGTT CTGGGAAAAGAGGACCCCTCTCTCCCCTCCAGCTGTGTGACCTTGTAACCTTAGACAACC TCTGAGCTTCTCTGAGCCTTGTTTGCTCATCTGGAAAAAGGGGATTAAACCATTTACCTC ATGGAGTTGTGAAAGAATAGCTGCAAAGCACCTAACACATAGTAAGGTTCCCAGTGCAGC TACTTCTGCTGGGTTGAGTCTAGCTGTGTAGGCCCCTTGTTCCTCACCTGGAGAAACTGG GGTGGCAGGCCGGTCCCCCACAAAAGATAACTCATCTCTTAATTTGCAAGCTGCCTCAAC AGGAGGGTGGGGGAACAGCTCAACAATGGCTGATGGGCGCTCCTGGTGTTGATAGAGATG GAACTTGGACTTGGAGGCCTCTCCACGCTGTCCCACTGCCCCTGGCCTAGGCAGCAGGTG AGTGGTTCTCCCAGTGACTCCTACCTGGTACTGAGGAAAGGCGGCTTGACTGGTGAGGGA GAGCAGGGCTTGGCTTGGGCAGCGGTTAGGTGTGGGAGGGAAAATGGTCAGGGAGGGACC AGGTGAATGGGAGGAGGAGCGGGACTTCTCTGAATGGTCGGTGCACTCAGGTGATTCCTC CCCTGGGCTCCCAGAGGCAGCAAACCCATTATACTGGAACCTAGGCCCTTCCTGAGTTTC CCCTCCACACAGCTAGGAGCCCATGCCCGGCCTGATCTCAGCCCGAGGACAGCCCCTCCT TGAGGTCCTTCCTCCCCAAGCCCACCTGGGTGCCCTCTTTCTCCCTGAGGCTCCACTTGG TCTCTCCGCGCAGCCTGCCCTGTGGCCCACCCTGGCCGCTCTGGCTCTGCTGAGCAGCGT CGCAGAGGCCTCCCTGGGCTCCGCGCCCCGCAGCCCTGCCCCCCGCGAAGGCCCCCCGCC TGTCCTGGCGTCCCCCGCCGGCCACCTGCCGGGTAGGTGAGAGGGCGAGGGGGCGGGGCG GGGCTGGCCCGGGACACCGCGCGTGACTGGGTCTCATTCCAGGGGGACGCACGGCCCGCT GGTGCAGTGGAAGAGCCCGGCGGCCGCCGCCGCAGCCTTCTCGGCCCGCGCCCCCGCCGC CTGCACCCCCATCTGCTCTTCCCCGCGGGGGCCGCGCGGCGCGGGCTGGGGGCCCGGGCA GCCGCGCTCGGGCAGCGGGGGCGCGGGGCTGCCGCCTGCGCTCGCAGCTGGTGCCGGTGC GCGCGCTCGGCCTGGGCCACCGCTCCGACGAGCTGGTGCGTTTCCGCTTCTGCAGCGGCT CCTGCCGCCGCGCGCGCTCTCCACACGACCTCAGCCTGGCCAGCCTACTGGGCGCCGGGG CCCTGCGACCGCCCCCGGGCTCCCGGCCCGTCAGCCAGCCCTGCTGCCGACCCACGCGCT ACGAAGCGGTCTCCTTCATGGACGTCAACAGCACCTGGAGAACCGTGGACCGCCTCTCCG CCACCGCCTGCGGCTGCCTGGGCTGAGGGCTCGCTCCAGGGCTTTGCAGACTGGACCCTT ACCGGTGGCTCTTCCTGCCTGGGACCCTCCCGCAGAGTCCCACTAGCCAGCGGCCTCAGC CAGGGACGAAGGCCTCAAAGCTGAGAGGCCCCTGCCGGTGGGTGATGGATATCATCCCCG AACAGGTGAAGGGACAACTGACTAGCAGCCCCAGAGCCCTCACCCTGCGGATCCCAGCCT AAAAGACACCAGAGACCTCAGCTATGGAGCCCTTCGGACCCACTTCTCACAGACTCTGGC ACTGGCCAGGCCTCGAACCTGGGACCCCTCCTCTGATGAACACTACAGTGGCTGAGGCAT CAGCCCCCGCCCAGGCCCTGTAGGGACAGCATTTGAAGGACACATATTGCAGTTGCTTGG TTGAAAGTGCCTGTGCTGGAACTGGCCTGTACTCACTCATGGGAGCTGGCCCCTATTTAT TATTTCTAAGTTATTTATTTA OMIM ID 603886