Entrez gene ID | | 91 |
Official gene symbol | | ACVR1B |
Full name | | activin A receptor, type IB |
Aliases | | ,ACTRIB,ACVRLK4,ALK4,SKR2, |
Gene summary | | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants. |
Location | | Chromosome: 12 Locus: 12q13 |
Gene position | | 52345451 - 52390863 Map Viewer |
Gene orientation | | plus |
Gene size | | 45413 bp |
Gene sequence |
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OMIM ID | | 601300 |