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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD1B (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 910 Official gene symbol CD1B Full name CD1b molecule Aliases ,CD1,CD1A,MGC125990,MGC125991,R1, Gene summary This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq] Location Chromosome: 1   Locus: 1q22-q23 Gene position 158301321 - 158297740  Map Viewer Gene orientation minus Gene size 3582 bp Gene sequence >CD1B:complement(9786382..9789963):Length=3582 GGCAGTTGGAAGAGAGAAGAAGTCACTACAGGGTACTGAGGAAAAGCTTTGCTGAAATTG GAGATCAAATACCAGCTCTGCCAGTAAGAAGTTGCATCTCCCAGTGAAATGCTGCTGCTG CCATTTCAACTGTTAGCTGTTCTCTTTCCTGGTGGTAACAGTGAACATGGTAAGAGTCAC TCTGGCAGCTCCCAGCACTGGTGCAGGGGTTTGGATTTTAAAAAGCAAGCAGGGCTTTCC TAGGTGCAATTGGACACTAAGGGTCTGGGTCTTTCTGTCTCCCGCCCTCTTCAACCATTC TGGTGGTTGGGACTAGAACCTGAAGCCTTAAGGCAGTCAAATGTGTCAGACTTCCTGTGT TCTTTAGACTCTAGGTTCTTGTTTTCTAAATCATTTTCATTCCCATTCTTCCTAATTGTC TCCTGCTTCTCTCTTTATCTTCACCATCTTGCTTTTCCACTCTTCACAGCCTTCCAGGGG CCGACCTCCTTTCATGTTATCCAGACCTCGTCCTTTACCAATAGTACCTGGGCACAAACT CAAGGCTCAGGCTGGTTGGATGATTTGCAGATTCATGGCTGGGATAGCGACTCAGGCACT GCCATATTCCTGAAGCCTTGGTCTAAAGGTAACTTTAGTGATAAGGAGGTTGCTGAGTTA GAGGAGATATTCCGAGTCTACATCTTTGGATTCGCTCGAGAAGTACAAGACTTTGCCGGT GATTTCCAGATGAAATGTGAGTCTAGTCCACCGAACTGGGAAGAGTCTCAAGGACTCTCT TTTCTCTCTTTTTTGCAAAGTGTTGCTCTCTCTGATGCTTCTCCCTTCCTTTCTATTTTA CCCAAATGCACGCACATGCTTTTCTTGAGTAGTCTCTCACTCCAGCTTCACACCATCACA CCTCATATTTCAGATTCTTGCTGCCTCTGCACTCTTCTCTTACTCTCAGACTGTCTTCCA CTTTGTAACCAGCTGCTGGTTTGTCTTATGTGAAACTTCTCCTCAAGGGCCCTTACTTCT CCTACCCTGTGCCTGAGTGATCTAACGTGTGGCTTTCTCCCCTAATCCATCTTTTCAATC ATCTCCTCCCCGCACCCTCCTCTTGCTGGGAACCTCCACTCACTCTGGAATGCTGCACTC CTGACTGCACCACGCTCTGCCTCACCTCTCCTTTCATACTCACTGTACTCCTTTATCACA TACCTTTGTCTTCATGGCATGCACATTTTTCTCAATGCTCTTGTTTCTGAAAATGTCTAA ATGTTATCATTAGTTTTTAGCTCATCATCATTTTACACCAAATAACTTTATCCCCACCAA AATCTAAAATCCTAGGTTCTTTTCTCATGCCTTTTTTTCTTATTTGTGTTTAATAACTTG CTCTCTTTTCCCTCTACATAGACCCCTTTGAGATCCAGGGCATAGCAGGCTGTGAGCTAC ATTCTGGAGGTGCCATAGTAAGCTTCCTGAGGGGAGCTCTAGGAGGATTGGATTTCCTGA GTGTCAAGAATGCTTCATGTGTGCCTTCCCCAGAAGGTGGCAGCAGGGCACAGAAATTCT GTGCACTAATCATACAATATCAAGGTATCATGGAAACTGTGAGAATTCTCCTCTATGAAA CCTGCCCCCGATATCTCTTGGGCGTCCTCAATGCAGGAAAAGCAGATCTGCAAAGACAAG GTTAGTCCTGCTGTTATTTCACTTCCCACCACCTCCTCTAAGATCAAGAGTAGGAAGATA TCAAAGGATAGGAGCTTAAATAACAAGTTATTTGGTTCCCAAAGGAGTGAATGGGGTCGC TGTCCAAGCTTGTAGGTTTCTGAGTTCATAACCTCTGAACTCGAGTTATAACATGACACT TTTTTTTCTCCTTCCTGCCTTAGTGAAGCCTGAGGCCTGGCTGTCCAGTGGCCCCAGTCC TGGACCTGGCCGTCTGCAGCTTGTGTGCCATGTCTCAGGATTCTACCCAAAGCCCGTGTG GGTGATGTGGATGCGGGGTGAGCAGGAGCAGCAGGGCACTCAGCTAGGGGACATCCTGCC CAATGCTAACTGGACATGGTATCTCCGAGCAACCCTGGATGTGGCAGATGGGGAGGCGGC TGGCCTGTCCTGTCGGGTGAAGCACAGCAGTTTAGAGGGCCAGGACATCATCCTCTACTG GAGTAAGAAATAGCAGGGACCCAGGCTGGAAATGCCAGGAAGTGATCTTCAGGCATAGAG GGAGGCACTGGGGAAGGATAGAGCTTGAGAGATGAAAGAGGGAGAGATTGATTGATTGAT TTCCCTGACCCCAATCCCAACAGGAGTAAAAATAGATAATCCAAGTTATCAAAAATGTAG GAATTAAGGACCTGTAAACTGGGTAGAGGGGATCAAAGGATGGATATATGGTGGCCAGGA ATATGAGAGAGGAAGTTGGAAATGACCATACATTGGAAGTAGGTGGGCAAAGGAAGGCCA AGGAATTCTGTGTATAGTATCTGAAGTGACATCCTTTTGTCCTCTCTCAATTGCCAGGAA ACCCCACCTCCATTGGCTCAATTGTTTTGGCAATAATAGTGCCTTCCTTGCTCCTTTTGC TATGCCTTGCATTATGGTATATGAGGCGCCGGTGAGTTGTGGGTGGTGTTGTTTTTTTTT TTAATATGTCTTTTCTGTTCACCCTTCCACTGTTTTTTACCATTTTATCTATTTAAAAAT TGTTTATCCTCAATCCTTTCACCATATCCTTTCCCCAAACTCCCATTCGTTTTATGTGGA CTTAAAAAAAATTCTGTTAAAATACACATAACATAAGGTTTACCATCTTTACCATTTTTA AGTGTACAGTTCAGTGGTGTTAAGTGTGTTCACATTGTTGTGCAAGCAATCTTCAAAACT CTTCTGTCTTGCAAGACTGAAACTCTATTCCTATTACGCTGCAAGTTCCCATTTCCCCTC TTCTCCAGGCCCTGGTTAGGACAGCTCTACATTCTGTCTCTATGAATTCTACTATTCTAG GTACCTTATATAAGTGGAATTGTAAATATTTGTCTTTTTGTGACTTATTTCATTTAGCGT AATATCCTCATTGTAGCATATGAAAGGGCTTCCTTCCTTTTTTGAAACTGAACAATATTC CACCATATGCGTATAACACATTTTGTTCATCCATTCGTCTATCTATGGACACTTGGGTTG CTTTCACTTTTAACTATCATGAATAATATTACTATGAGCATGGGTGTACAAACATCTTTT ATGTGGAGCTCTTTTGTTCTTCTGTTTTTAACAGGTCATATCAGAATATCCCATGAGCCA TCATCATGTCTCCTCTCCCATTCGCAATAAGTACCAAGAAGCCCAAGATATCAGCCCAAA AGTCAATCTTATCATATTTCAAATGATTTTCAAATTTGATGAAATCAGAGTTTTCATGTA TTTTAAAATAAATTATTATTTAAACATCAGCAAAAAAGTACTTAAAACTGTAAATTTATT ATGAGACTGTACTAACAGTGTGATTCACCCTGATTTTACACACATTAAAATGTTAGAAAA AATGTGTCTCAAAATAAATGAAATATAATACATATGACTTAA OMIM ID 188360