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Gene information for ATP6V0D1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9114
Official gene symbolATP6V0D1
Full nameATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
Aliases,ATP6D,ATP6DV,FLJ43534,P39,VATX,VMA6,VPATPD,
Gene summaryThis gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q22.1
Gene position67515089 - 67471917  Map Viewer
Gene orientationminus
Gene size43173 bp
Gene sequence
OMIM ID607028