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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for COX7A2L (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9167
Official gene symbolCOX7A2L
Full namecytochrome c oxidase subunit VIIa polypeptide 2 like
Aliases,COX7AR,COX7RP,EB1,SIG81,
Gene summaryCytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p21
Gene position42588356 - 42577642  Map Viewer
Gene orientationminus
Gene size10715 bp
Gene sequence
OMIM ID605771