Entrez gene ID | | 917 |
Official gene symbol | | CD3G |
Full name | | CD3g molecule, gamma (CD3-TCR complex) |
Aliases | | ,CD3-GAMMA,FLJ17620,FLJ17664,FLJ79544,FLJ94613,MGC138597,T3G, |
Gene summary | | The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q23 |
Gene position | | 118215059 - 118224497 Map Viewer |
Gene orientation | | plus |
Gene size | | 9439 bp |
Gene sequence |
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OMIM ID | | 186740 |
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