Entrez gene ID | | 9172 |
Official gene symbol | | MYOM2 |
Full name | | myomesin (M-protein) 2, 165kDa |
Aliases | | ,TTNAP, |
Gene summary | | The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p23.3 |
Gene position | | 1993158 - 2093380 Map Viewer |
Gene orientation | | plus |
Gene size | | 100223 bp |
Gene sequence |
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OMIM ID | | 603509 |
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