Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DDX21 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9188
Official gene symbolDDX21
Full nameDEAD (Asp-Glu-Ala-Asp) box polypeptide 21
Aliases,DKFZp686F21172,GUA,GURDB,RH-II/GU,RH-II/GuA,
Gene summaryDEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q21
Gene position70715892 - 70744279  Map Viewer
Gene orientationplus
Gene size28388 bp
Gene sequence
OMIM ID606357