Entrez gene ID | | 9188 |
Official gene symbol | | DDX21 |
Full name | | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 |
Aliases | | ,DKFZp686F21172,GUA,GURDB,RH-II/GU,RH-II/GuA, |
Gene summary | | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q21 |
Gene position | | 70715892 - 70744279 Map Viewer |
Gene orientation | | plus |
Gene size | | 28388 bp |
Gene sequence |
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OMIM ID | | 606357 |
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