Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID920
Official gene symbolCD4
Full nameCD4 molecule
Aliases,CD4mut,
Gene summaryThis gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12pter-p12
Gene position6898638 - 6929976  Map Viewer
Gene orientationplus
Gene size31339 bp
Gene sequence
OMIM ID186940